 DNA, Superhelical
"DNA, Superhelical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
| Descriptor ID |
D004278
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| MeSH Number(s) |
D13.444.308.283.250 G02.111.570.820.486.212.250 G05.360.580.156.250
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| Concept/Terms |
DNA, Superhelical- DNA, Superhelical
- Superhelical DNA
- DNA, Supertwisted
- Supertwisted DNA
- DNA, Supercoiled
- Supercoiled DNA
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Below are MeSH descriptors whose meaning is more general than "DNA, Superhelical".
Below are MeSH descriptors whose meaning is more specific than "DNA, Superhelical".
This graph shows the total number of publications written about "DNA, Superhelical" by people in this website by year, and whether "DNA, Superhelical" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA, Superhelical" by people in Profiles.
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Villain P, da Cunha V, Villain E, Forterre P, Oberto J, Catchpole R, Basta T. The hyperthermophilic archaeon Thermococcus kodakarensis is resistant to pervasive negative supercoiling activity of DNA gyrase. Nucleic Acids Res. 2021 12 02; 49(21):12332-12347.
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Lengsfeld CS, Munson L, Lentz YK, Anchordoquy TJ. DNA hydrodynamic degradation controlled by Kolomogorov length scales in pipe flow. J Pharm Sci. 2011 Aug; 100(8):3088-3095.
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Anchordoquy TJ, Molina Md, Kempner ES. A radiation target method for size determination of supercoiled plasmid DNA. Anal Biochem. 2009 Feb 15; 385(2):229-33.
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Ito M, Sakakura A, Miyazawa N, Murata S, Yoshikawa K. Nonspecificity induces chiral specificity in the folding transition of giant DNA. J Am Chem Soc. 2003 Oct 22; 125(42):12714-5.
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Alverson J, Bundle SF, Sohaskey CD, Lybecker MC, Samuels DS. Transcriptional regulation of the ospAB and ospC promoters from Borrelia burgdorferi. Mol Microbiol. 2003 Jun; 48(6):1665-77.
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Scott GK, Chang CH, Erny KM, Xu F, Fredericks WJ, Rauscher FJ, Thor AD, Benz CC. Ets regulation of the erbB2 promoter. Oncogene. 2000 Dec 18; 19(55):6490-502.
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Schneider R, Travers A, Kutateladze T, Muskhelishvili G. A DNA architectural protein couples cellular physiology and DNA topology in Escherichia coli. Mol Microbiol. 1999 Dec; 34(5):953-64.
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Shapiro PS, Whalen AM, Tolwinski NS, Wilsbacher J, Froelich-Ammon SJ, Garcia M, Osheroff N, Ahn NG. Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation. Mol Cell Biol. 1999 May; 19(5):3551-60.
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Kugel JF, Goodrich JA. Promoter escape limits the rate of RNA polymerase II transcription and is enhanced by TFIIE, TFIIH, and ATP on negatively supercoiled DNA. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9232-7.
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Kroll DJ, Sullivan DM, Gutierrez-Hartmann A, Hoeffler JP. Modification of DNA topoisomerase II activity via direct interactions with the cyclic adenosine-3',5'-monophosphate response element-binding protein and related transcription factors. Mol Endocrinol. 1993 Mar; 7(3):305-18.
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