 DNA, Circular
"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D004270
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| MeSH Number(s) |
D13.444.308.283 G02.111.570.820.486.212 G05.360.580.156
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| Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
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Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in this website by year, and whether "DNA, Circular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles.
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Sommers P, Fontenele RS, Kringen T, Kraberger S, Porazinska DL, Darcy JL, Schmidt SK, Varsani A. Single-Stranded DNA Viruses in Antarctic Cryoconite Holes. Viruses. 2019 11 04; 11(11).
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Hussmann JA, Lou DI, Sawyer SL, Press WH. Reply to Schmitt et al.: Data-filtering schemes for avoiding double-counting in circle sequencing. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):E1561.
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Lou DI, Hussmann JA, McBee RM, Acevedo A, Andino R, Press WH, Sawyer SL. High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19872-7.
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Betker J, Smyth T, Wang W, Anchordoquy TJ. Application of a ultra performance liquid chromatography method in the determination of DNA quality and stability. J Pharm Sci. 2012 Mar; 101(3):987-97.
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Stengel G, Kuchta RD. Coordinated leading and lagging strand DNA synthesis by using the herpes simplex virus 1 replication complex and minicircle DNA templates. J Virol. 2011 Jan; 85(2):957-67.
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Inagaki H, Ohye T, Kogo H, Kato T, Bolor H, Taniguchi M, Shaikh TH, Emanuel BS, Kurahashi H. Chromosomal instability mediated by non-B DNA: cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res. 2009 Feb; 19(2):191-8.
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Lengsfeld CS, Anchordoquy TJ. Shear-induced degradation of plasmid DNA. J Pharm Sci. 2002 Jul; 91(7):1581-9.
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Gaubatz JW, Flores SC. Purification of eucaryotic extrachromosomal circular DNAs using exonuclease III. Anal Biochem. 1990 Feb 01; 184(2):305-10.
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Gaubatz JW, Flores SC. Tissue-specific and age-related variations in repetitive sequences of mouse extrachromosomal circular DNAs. Mutat Res. 1990 Jan; 237(1):29-36.
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Flores SC, Sunnerhagen P, Moore TK, Gaubatz JW. Characterization of repetitive sequence families in mouse heart small polydisperse circular DNAs: age-related studies. Nucleic Acids Res. 1988 May 11; 16(9):3889-906.
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