beta 2-Glycoprotein I
"beta 2-Glycoprotein I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.
Descriptor ID |
D053482
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MeSH Number(s) |
D12.776.124.117 D12.776.395.195
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Concept/Terms |
beta 2-Glycoprotein I- beta 2-Glycoprotein I
- beta 2 Glycoprotein I
- Apo H
- Endothelial Cell-Viability Maintaining Factor
- Endothelial Cell Viability Maintaining Factor
- beta(2)GPI
- beta2-Glycoprotein I
- beta2 Glycoprotein I
- EC-VMFa
- EC VMFa
- Anticardiolipin Cofactor
- Cofactor, Anticardiolipin
- Apolipoprotein H
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Below are MeSH descriptors whose meaning is more general than "beta 2-Glycoprotein I".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Glycoprotein I".
This graph shows the total number of publications written about "beta 2-Glycoprotein I" by people in this website by year, and whether "beta 2-Glycoprotein I" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta 2-Glycoprotein I" by people in Profiles.
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Fleming SD, Egan RP, Chai C, Girardi G, Holers VM, Salmon J, Monestier M, Tsokos GC. Anti-phospholipid antibodies restore mesenteric ischemia/reperfusion-induced injury in complement receptor 2/complement receptor 1-deficient mice. J Immunol. 2004 Dec 01; 173(11):7055-61.
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Kobayashi K, Kishi M, Atsumi T, Bertolaccini ML, Makino H, Sakairi N, Yamamoto I, Yasuda T, Khamashta MA, Hughes GR, Koike T, Voelker DR, Matsuura E. Circulating oxidized LDL forms complexes with beta2-glycoprotein I: implication as an atherogenic autoantigen. J Lipid Res. 2003 Apr; 44(4):716-26.
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Liu Q, Kobayashi K, Furukawa J, Inagaki J, Sakairi N, Iwado A, Yasuda T, Koike T, Voelker DR, Matsuura E. Omega-carboxyl variants of 7-ketocholesteryl esters are ligands for beta(2)-glycoprotein I and mediate antibody-dependent uptake of oxidized LDL by macrophages. J Lipid Res. 2002 Sep; 43(9):1486-95.
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Mehdi H, Aston CE, Sanghera DK, Hamman RF, Kamboh MI. Genetic variation in the apolipoprotein H (beta2-glycoprotein I) gene affects plasma apolipoprotein H concentrations. Hum Genet. 1999 Jul-Aug; 105(1-2):63-71.
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Lynch A, Byers T, Emlen W, Rynes D, Shetterly SM, Hamman RF. Association of antibodies to beta2-glycoprotein 1 with pregnancy loss and pregnancy-induced hypertension: a prospective study in low-risk pregnancy. Obstet Gynecol. 1999 Feb; 93(2):193-8.
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Sanghera DK, Kristensen T, Hamman RF, Kamboh MI. Molecular basis of the apolipoprotein H (beta 2-glycoprotein I) protein polymorphism. Hum Genet. 1997 Jul; 100(1):57-62.
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Hassell KL, Kressin DC, Neumann A, Ellison R, Marlar RA. Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men. Blood Coagul Fibrinolysis. 1994 Aug; 5(4):455-62.
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