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Kathryn L Hassell

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone720/848-0300

    Collapse Research 
    Collapse research activities and funding
    R13HL083691     (HASSELL, KATHRYN L)Aug 4, 2006 - Jul 31, 2007
    NIH
    Consensus Conference Grant
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Walters MC, Eapen M, Liu Y, El Rassi F, Waller EK, Levine JE, Strouse JJ, Antin JH, Parikh SH, Bakshi N, Dampier C, Jaroscak JJ, Bergmann S, Wong T, Kota V, Pace B, Lekakis LJ, Lulla P, Nickel RS, Kasow KA, Popat U, Smith W, Yu L, DiFronzo N, Geller N, Kamani N, Klings ES, Hassell K, Mendizabal A, Sullivan K, Neuberg D, Krishnamurti L. Hematopoietic cell transplant compared with standard care in adolescents and young adults with sickle cell disease. Blood Adv. 2025 Mar 11; 9(5):955-965. PMID: 39471440.
      View in: PubMed
    2. Rana NK, Lisk C, Cendali F, Lucero MJ, Grier A, Setua S, Thangaraju K, Khan A, Reisz JA, Dzieciatkowska M, Pak DI, Swindle D, Danaher MX, Khan S, Westover N, Carter M, Hassell K, Nuss R, George G, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence is Present in Spleens and Livers from Berkeley Sickle Cell Anemia and ?-Thalassemia Mice. J Proteome Res. 2025 Mar 07; 24(3):1306-1316. PMID: 39947632.
      View in: PubMed
    3. Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension. Free Radic Biol Med. 2025 Mar 01; 229:458-473. PMID: 39862998.
      View in: PubMed
    4. Blotske K, Patel T, Trujillo T, Marlar M, Lind S, Kramer H, Hassell K, Kiser TH. Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients. Clin Appl Thromb Hemost. 2025 Jan-Dec; 31:10760296251319961. PMID: 39925048.
      View in: PubMed
    5. Miller JI, Hassell KL, Kellar-Guenther Y, Quesada S, West R, Sontag M. The Prevalence of Sickle Cell Disease in Colorado and Methodologies of the Colorado Sickle Cell Data Collection Program: Public Health Surveillance Study. JMIR Public Health Surveill. 2024 Dec 09; 10:e64995. PMID: 39652892.
      View in: PubMed
    6. Nuss R, Hassell K. Transition and Sickle Cell Disease. Pediatrics. 2024 Dec 01; 154(6). PMID: 39552227.
      View in: PubMed
    7. Treadwell M, Du L, Lawrence Y, Gaspar M, Hassell K, Shah S, Akpan M, Crook N, Taylor M, Gopal S. Tracking Telehealth Needs for Individuals With Sickle Cell Disease Through the COVID-19 Pandemic: A Cross-Sectional Survey Study. Health Sci Rep. 2024 Nov; 7(11):e70163. PMID: 39507678.
      View in: PubMed
    8. Lisk C, Cendali F, Setua S, Thangaraju K, Pak DI, Swindle D, Dzieciatkowska M, Gamboni F, Hassell K, Nuss R, George G, Davizon-Castillo P, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and ?-Thalassemia Mice. J Proteome Res. 2023 09 01; 22(9):2925-2935. PMID: 37606205.
      View in: PubMed
    9. Lisk C, Cendali F, Pak DI, Swindle D, Hassell K, Nuss R, George G, Davizon-Castillo P, Buehler PW, D'Alessandro A, Irwin DC. Moderate hypoxia induces metabolic divergence in circulating monocytes and tissue resident macrophages from Berkeley sickle cell anemia mice. Front Med (Lausanne). 2023; 10:1149005. PMID: 37502360.
      View in: PubMed
    10. Singh A, Sontag MK, Zhou M, Dasgupta M, Crume T, McLemore M, Galadanci N, Randall E, Steiner N, Brandow AM, Koch K, Field JJ, Hassell K, Snyder AB, Kanter J. Evaluating the Discriminatory Ability of the Sickle Cell Data Collection Program's Administrative Claims Case Definition in Identifying Adults With Sickle Cell Disease: Validation Study. JMIR Public Health Surveill. 2023 06 28; 9:e42816. PMID: 37379070.
      View in: PubMed
    11. Schofield JR, Hassell KL. What you need to know about migraine in Hughes syndrome patients. Lupus. 2023 Mar; 32(3):319-324. PMID: 36708185.
      View in: PubMed
    12. Dampier CD, Telen MJ, Wun T, Brown RC, Desai P, El Rassi F, Fuh B, Kanter J, Pastore Y, Rothman J, Taylor JG, Readett D, Sivamurthy KM, Tammara B, Tseng LJ, Lozier JN, Thackray H, Magnani JL, Hassell KL. A randomized clinical trial of the efficacy and safety of rivipansel for sickle cell vaso-occlusive crisis. Blood. 2023 01 12; 141(2):168-179. PMID: 35981565.
      View in: PubMed
    13. Thangaraju K, Setua S, Lisk C, Swindle D, Stephenson D, Dzieciatkowska M, Lamb DR, Moitra P, Pak D, Hassell K, George G, Nuss R, Davizon-Castillo P, Stenmark KR, D'Alessandro A, Irwin DC, Buehler PW. Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease. Clin Appl Thromb Hemost. 2023 Jan-Dec; 29:10760296231186144. PMID: 37469147.
      View in: PubMed
    14. Pettigrove V, Hassell K, Kellar C, Long S, MacMahon D, Myers J, Nguyen H, Walpitagama M. Catchment sourcing urban pesticide pollution using constructed wetlands in Melbourne, Australia. Sci Total Environ. 2023 Mar 10; 863:160556. PMID: 36502981.
      View in: PubMed
    15. McDonald S, Holland A, Simpson SL, Gadd JB, Bennett WW, Walker GW, Keough MJ, Cresswel T, Hassell KL. Metal forms and dynamics in urban stormwater runoff: New insights from diffusive gradients in thin-films (DGT) measurements. Water Res. 2022 Feb 01; 209:117967. PMID: 34936976.
      View in: PubMed
    16. Buehler PW, Swindle D, Pak DI, Fini MA, Hassell K, Nuss R, Wilkerson RB, D'Alessandro A, Irwin DC. Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features. Pulm Circ. 2021 Oct-Dec; 11(4):20458940211055996. PMID: 34777785.
      View in: PubMed
    17. Karoor V, Swindle D, Pak DI, Strassheim D, Fini MA, Dempsey E, Stenmark KR, Hassell K, Nuss R, Buehler PW, Irwin DC. Evidence supporting a role for circulating macrophages in the regression of vascular remodeling following sub-chronic exposure to hemoglobin plus hypoxia. Pulm Circ. 2021 Oct-Dec; 11(4):20458940211056806. PMID: 34777787.
      View in: PubMed
    18. Liles DK, Shah NR, Scullin B, Gordeuk VR, Smith WR, Kanter J, Achebe MM, Boccia R, Crary SE, Kraft WK, Archer N, Cataldo V, Hardesty BM, Idowu M, Desai PC, Ikeda A, Puthenveetil G, Hassell KL, Sarnaik S, Kutlar A. Long-term biological effects in sickle cell disease: insights from a post-crizanlizumab study. Br J Haematol. 2021 11; 195(4):e150-e153. PMID: 34611900.
      View in: PubMed
    19. Buehler PW, Swindle D, Pak DI, Ferguson SK, Majka SM, Karoor V, Moldovan R, Sintas C, Black J, Gentinetta T, Buzzi RM, Vallelian F, Wassmer A, Edler M, Bain J, Schu D, Hassell K, Nuss R, Schaer DJ, Irwin DC. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radic Biol Med. 2021 11 01; 175:95-107. PMID: 34478834.
      View in: PubMed
    20. Farrar JE, Trujillo TC, Mueller SW, Beltran L, Nguyen C, Hassell K, Kiser TH. Evaluation of a patient specific, targeted-intensity pharmacologic thromboprophylaxis protocol in hospitalized patients with COVID-19. J Thromb Thrombolysis. 2022 Feb; 53(2):446-453. PMID: 34410561.
      View in: PubMed
    21. Hammer MP, Adams M, Unmack PJ, Hassell KL, Bertozzi T. Surprising Pseudogobius: Molecular systematics of benthic gobies reveals new insights into estuarine biodiversity (Teleostei: Gobiiformes). Mol Phylogenet Evol. 2021 07; 160:107140. PMID: 33711446.
      View in: PubMed
    22. McDonald S, Hassell K, Cresswell T. Effect of short-term dietary exposure on metal assimilation and metallothionein induction in the estuarine fish Pseudogobius sp. Sci Total Environ. 2021 Jun 10; 772:145042. PMID: 33581533.
      View in: PubMed
    23. Rushing JS, Appiah L, Polotsky AJ, Murray S, Foust E, Hassell K, Roeca C. Ovarian stimulation for fertility preservation in an oncology patient with etonogestrel implant in place. J Assist Reprod Genet. 2021 Feb; 38(2):513-516. PMID: 33409752.
      View in: PubMed
    24. Schofield JR, Hughes HN, Birlea M, Hassell KL. A trial of antithrombotic therapy in patients with refractory migraine and antiphospholipid antibodies: A retrospective study of 75 patients. Lupus. 2021 Apr; 30(4):568-577. PMID: 33402037.
      View in: PubMed
    25. Cabana MD, Marsh A, Treadwell MJ, Stemmler P, Rowland M, Bender MA, Bhasin N, Chung JH, Hassell K, Abdul Rashid NFN, Wong TE, Bardach NS. Improving Preventive Care for Children With Sickle Cell Anemia: A Quality Improvement Initiative. Pediatr Qual Saf. 2021 Jan-Feb; 6(1):e379. PMID: 33409431.
      View in: PubMed
    26. Bender MA, Yusuf C, Davis T, Dorley MC, Del Pilar Aguinaga M, Ingram A, Chan MS, Ubaike JC, Hassell K, Ojodu J, Hulihan M. Newborn Screening Practices and Alpha-Thalassemia Detection - United States, 2016. MMWR Morb Mortal Wkly Rep. 2020 Sep 11; 69(36):1269-1272. PMID: 32915167.
      View in: PubMed
    27. McDonald S, Cresswell T, Hassell K. Bioaccumulation kinetics of cadmium and zinc in the freshwater decapod crustacean Paratya australiensis following multiple pulse exposures. Sci Total Environ. 2020 Jun 10; 720:137609. PMID: 32145633.
      View in: PubMed
    28. Hassell KL, Coggan TL, Cresswell T, Kolobaric A, Berry K, Crosbie ND, Blackbeard J, Pettigrove VJ, Clarke BO. Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and Hexafluoropropylene Oxide Dimer Acid (GenX) in a Benthic Fish. Environ Toxicol Chem. 2020 03; 39(3):595-603. PMID: 31751491.
      View in: PubMed
    29. Long SM, Tull DL, De Souza DP, Kouremenos KA, Dayalan S, McConville MJ, Hassell KL, Pettigrove VJ, Gagnon MM. Metabolomics Provide Sensitive Insights into the Impacts of Low Level Environmental Contamination on Fish Health-A Pilot Study. Metabolites. 2020 Jan 06; 10(1). PMID: 31935843.
      View in: PubMed
    30. Farrell AT, Panepinto J, Desai AA, Kassim AA, Lebensburger J, Walters MC, Bauer DE, Blaylark RM, DiMichele DM, Gladwin MT, Green NS, Hassell K, Kato GJ, Klings ES, Kohn DB, Krishnamurti L, Little J, Makani J, Malik P, McGann PT, Minniti C, Morris CR, Odame I, Oneal PA, Setse R, Sharma P, Shenoy S. End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Adv. 2019 12 10; 3(23):4002-4020. PMID: 31809537.
      View in: PubMed
    31. Gaw S, Harford A, Pettigrove V, Sevicke-Jones G, Manning T, Ataria J, Cresswell T, Dafforn KA, Leusch FD, Moggridge B, Cameron M, Chapman J, Coates G, Colville A, Death C, Hageman K, Hassell K, Hoak M, Gadd J, Jolley DF, Karami A, Kotzakoulakis K, Lim R, McRae N, Metzeling L, Mooney T, Myers J, Pearson A, Saaristo M, Sharley D, Stuthe J, Sutherland O, Thomas O, Tremblay L, Wood W, Boxall AB, Rudd MA, Brooks BW. Towards Sustainable Environmental Quality: Priority Research Questions for the Australasian Region of Oceania. Integr Environ Assess Manag. 2019 Nov; 15(6):917-935. PMID: 31273905.
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    32. Redinus K, Baek JH, Yalamanoglu A, Shin HKH, Moldova R, Harral JW, Swindle D, Pak D, Ferguson SK, Nuss R, Hassell K, Nozik-Grayck E, Palmer AF, Fini MA, Karoor V, Stenmark KR, Buehler PW, Irwin DC. An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease. JCI Insight. 2019 08 08; 4(15). PMID: 31391342.
      View in: PubMed
    33. Ehrlich O, Karamalakis A, Krylov AJ, Dudczig S, Hassell KL, Jusuf PR. Clove Oil and AQUI-S Efficacy for Zebrafish Embryo, Larva, and Adult Anesthesia. Zebrafish. 2019 10; 16(5):451-459. PMID: 31188070.
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    34. Su L, Nan B, Hassell KL, Craig NJ, Pettigrove V. Microplastics biomonitoring in Australian urban wetlands using a common noxious fish (Gambusia holbrooki). Chemosphere. 2019 Aug; 228:65-74. PMID: 31022621.
      View in: PubMed
    35. Krishnamurti L, Neuberg DS, Sullivan KM, Kamani NR, Abraham A, Campigotto F, Zhang W, Dahdoul T, De Castro L, Parikh S, Bakshi N, Haight A, Hassell KL, Loving R, Rosenthal J, Smith SL, Smith W, Spearman M, Stevenson K, Wu CJ, Wiedl C, Waller EK, Walters MC. Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study. Am J Hematol. 2019 04; 94(4):446-454. PMID: 30637784.
      View in: PubMed
    36. Naik RP, Smith-Whitley K, Hassell KL, Umeh NI, de Montalembert M, Sahota P, Haywood C, Jenkins J, Lloyd-Puryear MA, Joiner CH, Bonham VL, Kato GJ. Clinical Outcomes Associated With Sickle Cell Trait: A Systematic Review. Ann Intern Med. 2018 11 06; 169(9):619-627. PMID: 30383109.
      View in: PubMed
    37. Lanzkron S, Sawicki GS, Hassell KL, Konstan MW, Liem RI, McColley SA. Transition to adulthood and adult health care for patients with sickle cell disease or cystic fibrosis: Current practices and research priorities. J Clin Transl Sci. 2018 Oct; 2(5):334-342. PMID: 30828476.
      View in: PubMed
    38. Hassell KL, Rawson CA, Gagnon MM. First report of intersex in a lutjanid: the goldband snapper Pristipomoides multidens. J Fish Biol. 2018 Aug; 93(2):428-431. PMID: 29971763.
      View in: PubMed
    39. Ferguson SK, Redinius K, Yalamanoglu A, Harral JW, Hyen Baek J, Pak D, Loomis Z, Hassell D, Eigenberger P, Nozik-Grayck E, Nuss R, Hassell K, Stenmark KR, Buehler PW, Irwin DC. Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia. J Physiol. 2019 02; 597(4):1073-1085. PMID: 29931797.
      View in: PubMed
    40. Yalamanoglu A, Deuel JW, Hunt RC, Baek JH, Hassell K, Redinius K, Irwin DC, Schaer DJ, Buehler PW. Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L765-L774. PMID: 30047285.
      View in: PubMed
    41. Sontag MK, Sarkar D, Comeau AM, Hassell K, Botto LD, Parad R, Rose SR, Wintergerst KA, Smith-Whitley K, Singh S, Yusuf C, Ojodu J, Copeland S, Hinton CF. Case Definitions for Conditions Identified by Newborn Screening Public Health Surveillance. Int J Neonatal Screen. 2018; 4(2):16. PMID: 29862374.
      View in: PubMed
    42. Eckman JR, Hassell KL, Huggins W, Werner EM, Klings ES, Adams RJ, Panepinto JA, Hamilton CM. Standard measures for sickle cell disease research: the PhenX Toolkit sickle cell disease collections. Blood Adv. 2017 Dec 26; 1(27):2703-2711. PMID: 29296922.
      View in: PubMed
    43. Hulihan M, Hassell KL, Raphael JL, Smith-Whitley K, Thorpe P. CDC Grand Rounds: Improving the Lives of Persons with Sickle Cell Disease. MMWR Morb Mortal Wkly Rep. 2017 Nov 24; 66(46):1269-1271. PMID: 29166365.
      View in: PubMed
    44. Schofield JR, Hassell K. Dosing considerations in the use of the direct oral anticoagulants in the antiphospholipid syndrome. J Clin Pharm Ther. 2018 Feb; 43(1):104-106. PMID: 28656623.
      View in: PubMed
    45. Keller S, Yang M, Treadwell MJ, Hassell KL. Sensitivity of alternative measures of functioning and wellbeing for adults with sickle cell disease: comparison of PROMIS? to ASCQ-Me?. Health Qual Life Outcomes. 2017 Jun 02; 15(1):117. PMID: 28577358.
      View in: PubMed
    46. Fu D, Bridle A, Leef M, Gagnon MM, Hassell KL, Nowak BF. Using a multi-biomarker approach to assess the effects of pollution on sand flathead (Platycephalus bassensis) from Port Phillip Bay, Victoria, Australia. Mar Pollut Bull. 2017 Jun 15; 119(1):211-219. PMID: 28392090.
      View in: PubMed
    47. Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik-Grayck E, Ferguson SK, Hassell K, Nuss R, Stenmark K, Buehler P, Irwin DC. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS One. 2017; 12(2):e0171219. PMID: 28152051.
      View in: PubMed
    48. Dampier C, Palermo TM, Darbari DS, Hassell K, Smith W, Zempsky W. AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain. J Pain. 2017 05; 18(5):490-498. PMID: 28065813.
      View in: PubMed
    49. Morris L, Colombo V, Hassell K, Kellar C, Leahy P, Long SM, Myers JH, Pettigrove V. Municipal wastewater effluent licensing: A global perspective and recommendations for best practice. Sci Total Environ. 2017 Feb 15; 580:1327-1339. PMID: 28017416.
      View in: PubMed
    50. Baker JK, Long SM, Hassell KL, Pettigrove VJ, Gagnon MM. Health Status of Sand Flathead (Platycephalus bassensis), Inhabiting an Industrialised and Urbanised Embayment, Port Phillip Bay, Victoria as Measured by Biomarkers of Exposure and Effects. PLoS One. 2016; 11(10):e0164257. PMID: 27711198.
      View in: PubMed
    51. Evensen CT, Treadwell MJ, Keller S, Levine R, Hassell KL, Werner EM, Smith WR. Quality of care in sickle cell disease: Cross-sectional study and development of a measure for adults reporting on ambulatory and emergency department care. Medicine (Baltimore). 2016 Aug; 95(35):e4528. PMID: 27583862.
      View in: PubMed
    52. Hassell KL. Sickle Cell Disease: A Continued Call to Action. Am J Prev Med. 2016 07; 51(1 Suppl 1):S1-2. PMID: 27320458.
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    53. Hinton CF, Homer CJ, Thompson AA, Williams A, Hassell KL, Feuchtbaum L, Berry SA, Comeau AM, Therrell BL, Brower A, Harris KB, Brown C, Monaco J, Ostrander RJ, Zuckerman AE, Kaye C, Dougherty D, Greene C, Green NS. A framework for assessing outcomes from newborn screening: on the road to measuring its promise. Mol Genet Metab. 2016 08; 118(4):221-9. PMID: 27268406.
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    54. Hassell K, Pettigrove V, Beresford N, Jobling S, Kumar A. No evidence of exposure to environmental estrogens in two feral fish species sampled from the Yarra River, Australia: A comparison with Northern Hemisphere studies. Ecotoxicol Environ Saf. 2016 Sep; 131:104-17. PMID: 27228034.
      View in: PubMed
    55. Gagnon MM, Baker JK, Long SM, Hassell KL, Pettigrove VJ. Contaminant (PAHs, OCs, PCBs and trace metals) concentrations are declining in axial tissue of sand flathead (Platycephalus bassensis) collected from an urbanised catchment (Port Phillip Bay, Australia). Mar Pollut Bull. 2016 Aug 15; 109(1):661-666. PMID: 27207026.
      View in: PubMed
    56. Thomas OR, Barbee NC, Hassell KL, Swearer SE. Smell no evil: Copper disrupts the alarm chemical response in a diadromous fish, Galaxias maculatus. Environ Toxicol Chem. 2016 09; 35(9):2209-14. PMID: 27552396.
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    57. Luchtman-Jones L, Pressel S, Hilliard L, Brown RC, Smith MG, Thompson AA, Lee MT, Rothman J, Rogers ZR, Owen W, Imran H, Thornburg C, Kwiatkowski JL, Aygun B, Nelson S, Roberts C, Gauger C, Piccone C, Kalfa T, Alvarez O, Hassell K, Davis BR, Ware RE. Effects of hydroxyurea treatment for patients with hemoglobin SC disease. Am J Hematol. 2016 Feb; 91(2):238-42. PMID: 26615793.
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    58. Walters MC, De Castro LM, Sullivan KM, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell KL, Farnia S, Campbell A, Petersdorf E. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Biol Blood Marrow Transplant. 2016 Feb; 22(2):207-211. PMID: 26500093.
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    59. Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers FA. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. Br J Haematol. 2015 Jun; 169(6):887-98. PMID: 25907665.
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    60. Savage WJ, Buchanan GR, Yawn BP, Afenyi-Annan AN, Ballas SK, Goldsmith JC, Hassell KL, James AH, John-Sowah J, Jordan L, Lottenberg R, Murad MH, Ortiz E, Tanabe PJ, Ware RE, Lanzkron SM. Evidence gaps in the management of sickle cell disease: A summary of needed research. Am J Hematol. 2015 Apr; 90(4):273-5. PMID: 25639238.
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    61. Irwin DC, Baek JH, Hassell K, Nuss R, Eigenberger P, Lisk C, Loomis Z, Maltzahn J, Stenmark KR, Nozik-Grayck E, Buehler PW. Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration. Free Radic Biol Med. 2015 May; 82:50-62. PMID: 25656991.
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    62. Yawn BP, Buchanan G, Hassell K. Management of patients with sickle cell disease--reply. JAMA. 2015 Jan 06; 313(1):91-2. PMID: 25562275.
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    63. Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R. The splenic syndrome in individuals with sickle cell trait. High Alt Med Biol. 2014 Dec; 15(4):468-71. PMID: 25361178.
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    64. Quirolo K, Bertolone S, Hassell K, Howard T, King KE, Rhodes DK, Bill J. The evaluation of a new apheresis device for automated red blood cell exchange procedures in patients with sickle cell disease. Transfusion. 2015 Apr; 55(4):775-81. PMID: 25330984.
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    65. Anderson M, Hassell KL, Trujillo TC, Wolfe B. When patients on target-specific oral anticoagulants need surgery. Cleve Clin J Med. 2014 Oct; 81(10):629-39. PMID: 25274657.
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    66. Treadwell MJ, Hassell K, Levine R, Keller S. Adult sickle cell quality-of-life measurement information system (ASCQ-Me): conceptual model based on review of the literature and formative research. Clin J Pain. 2014 Oct; 30(10):902-14. PMID: 24300219.
      View in: PubMed
    67. Yawn BP, Buchanan GR, Afenyi-Annan AN, Ballas SK, Hassell KL, James AH, Jordan L, Lanzkron SM, Lottenberg R, Savage WJ, Tanabe PJ, Ware RE, Murad MH, Goldsmith JC, Ortiz E, Fulwood R, Horton A, John-Sowah J. Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members. JAMA. 2014 Sep 10; 312(10):1033-48. PMID: 25203083.
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    68. Keller SD, Yang M, Treadwell MJ, Werner EM, Hassell KL. Patient reports of health outcome for adults living with sickle cell disease: development and testing of the ASCQ-Me item banks. Health Qual Life Outcomes. 2014 Aug 22; 12:125. PMID: 25146160.
      View in: PubMed
    69. Hassell KL, Afenyi-Annan A, Ballas SK, Buchanan GR, Eckman JR, Jordan L, Lanzkron S, Lottenberg R, Ware R. Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption. Am J Respir Crit Care Med. 2014 Jul 15; 190(2):237-8. PMID: 25025359.
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    70. Babilonia KM, Golightly LK, Gutman JA, Hassell KL, Kaiser JN, Kiser TH, Klem PM, Trujillo TC. Antithrombotic therapy in patients with thrombocytopenic cancer: outcomes associated with reduced-dose, low-molecular-weight heparin during hospitalization. Clin Appl Thromb Hemost. 2014 Nov; 20(8):799-806. PMID: 25022565.
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    71. Gladwin MT, Barst RJ, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Castro OL, Taylor JG, Goldsmith JC, Kato GJ, Gordeuk VR, Machado RF. Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom. PLoS One. 2014; 9(7):e99489. PMID: 24988120.
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    72. Lisk C, Kominsky D, Ehrentraut S, Bonaventura J, Nuss R, Hassell K, Nozik-Grayck E, Irwin DC. Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism. Am J Respir Cell Mol Biol. 2013 Oct; 49(4):619-26. PMID: 23713977.
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    73. Shanthanagouda AH, Nugegoda D, Hassell KL, Patil JG. Exposure to estrogenic chemicals induces ectopic expression of vtg in the testis of rainbowfish, Melanotaenia fluviatilis. Bull Environ Contam Toxicol. 2013 Oct; 91(4):438-43. PMID: 23934007.
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    74. Delaney KM, Axelrod KC, Buscetta A, Hassell KL, Adams-Graves PE, Seamon C, Kato GJ, Minniti CP. Leg ulcers in sickle cell disease: current patterns and practices. Hemoglobin. 2013; 37(4):325-32. PMID: 23600469.
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    75. Kirwan GM, Hancock T, Hassell K, Niere JO, Nugegoda D, Goto S, Adams MJ. Nuclear magnetic resonance metabonomic profiling using tO2PLS. Anal Chim Acta. 2013 Jun 05; 781:33-40. PMID: 23684462.
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    76. Ferguson EM, Allinson M, Allinson G, Swearer SE, Hassell KL. Fluctuations in natural and synthetic estrogen concentrations in a tidal estuary in south-eastern Australia. Water Res. 2013 Mar 15; 47(4):1604-15. PMID: 23305682.
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    77. Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica. 2013 Mar; 98(3):464-72. PMID: 22983573.
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    78. Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JG, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR. Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom. Circulation. 2011 Sep 27; 124(13):1452-60. PMID: 21900080.
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    79. Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol. 2011 Aug; 154(3):387-97. PMID: 21592110.
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    80. Smith WR, Jordan LB, Hassell KL. Frequently asked questions by hospitalists managing pain in adults with sickle cell disease. J Hosp Med. 2011 May; 6(5):297-303. PMID: 21661104.
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    81. Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC, Gladwin MT. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood. 2011 Jul 28; 118(4):855-64. PMID: 21527519.
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    82. Kiser TH, Mann AM, Trujillo TC, Hassell KL. Evaluation of empiric versus nomogram-based direct thrombin inhibitor management in patients with suspected heparin-induced thrombocytopenia. Am J Hematol. 2011 Mar; 86(3):267-72. PMID: 21328434.
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    83. Hassell KL. Pulmonary hypertension, tricuspid regurgitant velocity screening, and the nitric oxide pathway. Hematology Am Soc Hematol Educ Program. 2011; 2011:419-26. PMID: 22160068.
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    84. Kiser TH, MacLaren R, Fish DN, Hassell KL, Teitelbaum I. Bivalirudin versus unfractionated heparin for prevention of hemofilter occlusion during continuous renal replacement therapy. Pharmacotherapy. 2010 Nov; 30(11):1117-26. PMID: 20973685.
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    85. Tanabe P, Porter J, Creary M, Kirkwood E, Miller S, Ahmed-Williams E, Hassell K. A qualitative analysis of best self-management practices: sickle cell disease. J Natl Med Assoc. 2010 Nov; 102(11):1033-41. PMID: 21141291.
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    86. Hassell KL. Population estimates of sickle cell disease in the U.S. Am J Prev Med. 2010 Apr; 38(4 Suppl):S512-21. PMID: 20331952.
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    87. Hassell K, Pace B, Wang W, Kulkarni R, Luban N, Johnson CS, Eckman J, Lane P, Woods WG. Sickle cell disease summit: from clinical and research disparity to action. Am J Hematol. 2009 Jan; 84(1):39-45. PMID: 19021119.
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    88. Hassell K. Heparin-induced thrombocytopenia: diagnosis and management. Thromb Res. 2008; 123 Suppl 1:S16-21. PMID: 18829068.
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    89. Pratte KA, Bar?n AE, Ogden LG, Hassell KL, Rewers M, Hokanson JE. Plasminogen activator inhibitor-1 is associated with coronary artery calcium in Type 1 diabetes. J Diabetes Complications. 2009 Nov-Dec; 23(6):387-93. PMID: 18768333.
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    90. Kiser TH, Burch JC, Klem PM, Hassell KL. Safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia. Pharmacotherapy. 2008 Sep; 28(9):1115-24. PMID: 18752382.
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    91. Lanzkron S, Haywood C, Hassell KL, Rand C. Provider barriers to hydroxyurea use in adults with sickle cell disease: a survey of the Sickle Cell Disease Adult Provider Network. J Natl Med Assoc. 2008 Aug; 100(8):968-73. PMID: 18717150.
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    92. Hassell KL, Coutin PC, Nugegoda D. Hypoxia impairs embryo development and survival in black bream (Acanthopagrus butcheri). Mar Pollut Bull. 2008; 57(6-12):302-6. PMID: 18420223.
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    93. Codi King S, Hassell K, Nugegoda D, Kristiansen SI. The assessment of vitellogenin as a biomarker of exposure to estrogenic compounds in two Australian perciformes. Mar Environ Res. 2008 Jul; 66(1):116-8. PMID: 18377978.
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    94. Kluger BM, Hughes RL, Anderson CA, Hassell KL. Non-traumatic carotid dissection and stroke associated with anti-phospholipid antibody syndrome: report of a case and review of the literature. Neurol India. 2008 Jan-Mar; 56(1):77-8. PMID: 18310845.
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    95. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T. A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br J Haematol. 2007 Feb; 136(3):501-8. PMID: 17233848.
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    96. Dowling NF, Beckman MG, Manco-Johnson M, Hassell K, Philipp CS, Michaels LA, Moll S, Heit JA, Penner J, Kulkarni R, Pipe S, Bockenstedt P, Andersen J, Crudder S, James AH, Zimmerman S, Ortel TL. The U.S. Thrombosis and Hemostasis Centers pilot sites program. J Thromb Thrombolysis. 2007 Feb; 23(1):1-7. PMID: 17111206.
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    97. Hassell KL, Kefford BJ, Nugegoda D. Sub-lethal and chronic salinity tolerances of three freshwater insects: Cloeon sp. and Centroptilum sp. (Ephemeroptera: Baetidae) and Chironomus sp. (Diptera: Chironomidae). J Exp Biol. 2006 Oct; 209(Pt 20):4024-32. PMID: 17023596.
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    98. Hassell K. Pregnancy and sickle cell disease. Hematol Oncol Clin North Am. 2005 Oct; 19(5):903-16, vii-viii. PMID: 16214651.
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    99. Hassell K. The management of patients with heparin-induced thrombocytopenia who require anticoagulant therapy. Chest. 2005 Feb; 127(2 Suppl):1S-8S. PMID: 15706025.
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    100. Hassell KL. Hematologic ramifications of patent foramen ovale--role of hypercoagulable state. Cardiol Clin. 2005 Feb; 23(1):65-71. PMID: 15676269.
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    101. Lottenberg R, Hassell KL. An evidence-based approach to the treatment of adults with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2005; 58-65. PMID: 16304360.
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    102. Dodge SM, Hassell K, Anderson CA, Keller J, Groves B, Carroll JD. Antiphospholipid antibodies are common in patients referred for percutaneous patent foramen ovale closure. Catheter Cardiovasc Interv. 2004 Jan; 61(1):123-7. PMID: 14696171.
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    103. Hassell KL. Altered hemostasis in pulmonary hypertension. Blood Coagul Fibrinolysis. 1998 Mar; 9(2):107-17. PMID: 9622208.
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    104. Neumayr L, Koshy M, Haberkern C, Earles AN, Bellevue R, Hassell K, Miller S, Black D, Vichinsky E. Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group. Am J Hematol. 1998 Feb; 57(2):101-8. PMID: 9462540.
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    105. Welsh CH, Hassell KL, Badesch DB, Kressin DC, Marlar RA. Coagulation and fibrinolytic profiles in patients with severe pulmonary hypertension. Chest. 1996 Sep; 110(3):710-7. PMID: 8797416.
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    106. Lane PA, O'Connell JL, Lear JL, Rogers ZR, Woods GM, Hassell KL, Wethers DL, Luckey DW, Buchanan GR. Functional asplenia in hemoglobin SC disease. Blood. 1995 Apr 15; 85(8):2238-44. PMID: 7718896.
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    107. Santhosh-Kumar CR, Deutsch JC, Hassell KL, Kolhouse NM, Kolhouse JF. Quantitation of red blood cell folates by stable isotope dilution gas chromatography-mass spectrometry utilizing a folate internal standard. Anal Biochem. 1995 Feb 10; 225(1):1-9. PMID: 7778757.
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    108. Santhosh-Kumar CR, Hassell KL, Deutsch JC, Kolhouse JF. Are neuropsychiatric manifestations of folate, cobalamin and pyridoxine deficiency mediated through imbalances in excitatory sulfur amino acids? Med Hypotheses. 1994 Oct; 43(4):239-44. PMID: 7838008.
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    109. Santhosh-Kumar CR, Deutsch JC, Kolhouse JC, Hassell KL, Kolhouse JF. Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring. Anal Biochem. 1994 Aug 01; 220(2):249-56. PMID: 7978266.
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    110. Hassell KL, Kressin DC, Neumann A, Ellison R, Marlar RA. Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men. Blood Coagul Fibrinolysis. 1994 Aug; 5(4):455-62. PMID: 7841299.
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    111. Hassell KL, Eckman JR, Lane PA. Acute multiorgan failure syndrome: a potentially catastrophic complication of severe sickle cell pain episodes. Am J Med. 1994 Feb; 96(2):155-62. PMID: 8109600.
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