 Pyrogens
"Pyrogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances capable of increasing BODY TEMPERATURE and cause FEVER and may be used for FEVER THERAPY. They may be of microbial origin, often POLYSACCHARIDES, and may contaminate distilled water.
| Descriptor ID |
D011749
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| MeSH Number(s) |
D27.888.569.673
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrogens".
Below are MeSH descriptors whose meaning is more specific than "Pyrogens".
This graph shows the total number of publications written about "Pyrogens" by people in this website by year, and whether "Pyrogens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrogens" by people in Profiles.
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Dinarello CA. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J Endotoxin Res. 2004; 10(4):201-22.
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Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis. 1999 Mar; 179 Suppl 2:S294-304.
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Dinarello CA, Gatti S, Bartfai T. Fever: links with an ancient receptor. Curr Biol. 1999 Feb 25; 9(4):R147-50.
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Dinarello CA. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann N Y Acad Sci. 1998 Sep 29; 856:1-11.
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Opp MR, Toth LA. Circadian modulation of interleukin-1-induced fever in intact and vagotomized rats. Ann N Y Acad Sci. 1997 Mar 15; 813:435-6.
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Dinarello CA. Thermoregulation and the pathogenesis of fever. Infect Dis Clin North Am. 1996 Jun; 10(2):433-49.
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Wakabayashi G, Cannon JG, Gelfand JA, Clark BD, Aiura K, Burke JF, Wolff SM, Dinarello CA. Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits. Am J Physiol. 1994 Jul; 267(1 Pt 2):R329-36.
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Shapiro L, Zhang XX, Rupp RG, Wolff SM, Dinarello CA. Ciliary neurotrophic factor is an endogenous pyrogen. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8614-8.
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Opp MR, Postlethwaite AE, Seyer JM, Krueger JM. Interleukin 1 receptor antagonist blocks somnogenic and pyrogenic responses to an interleukin 1 fragment. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):3726-30.
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Dinarello CA, Cannon JG, Mancilla J, Bishai I, Lees J, Coceani F. Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells. Brain Res. 1991 Oct 25; 562(2):199-206.
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