Cardiotoxins
"Cardiotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that have a damaging effect on the HEART. Such damage can occur from ALKYLATING AGENTS; FREE RADICALS; or metabolites from OXIDATIVE STRESS and in some cases is countered by CARDIOTONIC AGENTS. Induction of LONG QT SYNDROME or TORSADES DE POINTES has been the reason for viewing some drugs as cardiotoxins.
Descriptor ID |
D054715
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MeSH Number(s) |
D27.888.569.142
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Concept/Terms |
Cardiotoxins- Cardiotoxins
- Cardiotoxic Agents
- Agents, Cardiotoxic
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Below are MeSH descriptors whose meaning is more general than "Cardiotoxins".
Below are MeSH descriptors whose meaning is more specific than "Cardiotoxins".
This graph shows the total number of publications written about "Cardiotoxins" by people in this website by year, and whether "Cardiotoxins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cardiotoxins" by people in Profiles.
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Jones RL, Bendell JC, Smith DC, Diefenbach K, Lettieri J, Boix O, Lockhart AC, O'Bryant C, Moore KN. A phase I open-label trial evaluating the cardiovascular safety of regorafenib in patients with advanced cancer. Cancer Chemother Pharmacol. 2015 Oct; 76(4):777-84.
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Putt M, Hahn VS, Januzzi JL, Sawaya H, Sebag IA, Plana JC, Picard MH, Carver JR, Halpern EF, Kuter I, Passeri J, Cohen V, Banchs J, Martin RP, Gerszten RE, Scherrer-Crosbie M, Ky B. Longitudinal Changes in Multiple Biomarkers Are Associated with Cardiotoxicity in Breast Cancer Patients Treated with Doxorubicin, Taxanes, and Trastuzumab. Clin Chem. 2015 Sep; 61(9):1164-72.
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Harvey PA, Leinwand LA. Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor. Mol Cell Endocrinol. 2015 Jan 05; 399:330-5.
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Bair SM, Choueiri TK, Moslehi J. Cardiovascular complications associated with novel angiogenesis inhibitors: emerging evidence and evolving perspectives. Trends Cardiovasc Med. 2013 May; 23(4):104-13.
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Yousif NG, Al-Amran FG. Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice. BMC Cardiovasc Disord. 2011 Oct 14; 11:62.
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