 Chromatin Immunoprecipitation
"Chromatin Immunoprecipitation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technique for identifying specific DNA sequences that are bound, in vivo, to proteins of interest. It involves formaldehyde fixation of CHROMATIN to crosslink the DNA-BINDING PROTEINS to the DNA. After shearing the DNA into small fragments, specific DNA-protein complexes are isolated by immunoprecipitation with protein-specific ANTIBODIES. Then, the DNA isolated from the complex can be identified by PCR amplification and sequencing.
| Descriptor ID |
D047369
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| MeSH Number(s) |
E05.393.170 E05.478.605.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromatin Immunoprecipitation".
Below are MeSH descriptors whose meaning is more specific than "Chromatin Immunoprecipitation".
This graph shows the total number of publications written about "Chromatin Immunoprecipitation" by people in this website by year, and whether "Chromatin Immunoprecipitation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2005 | 0 | 1 | 1 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 5 | 5 | | 2008 | 0 | 5 | 5 | | 2009 | 1 | 8 | 9 | | 2010 | 0 | 8 | 8 | | 2011 | 1 | 8 | 9 | | 2012 | 0 | 4 | 4 | | 2013 | 2 | 10 | 12 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 8 | 8 | | 2016 | 1 | 8 | 9 | | 2017 | 1 | 6 | 7 | | 2018 | 0 | 2 | 2 | | 2020 | 0 | 4 | 4 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chromatin Immunoprecipitation" by people in Profiles.
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Kraft K, Yost KE, Murphy SE, Magg A, Long Y, Corces MR, Granja JM, Wittler L, Mundlos S, Cech TR, Boettiger AN, Chang HY. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proc Natl Acad Sci U S A. 2022 05 31; 119(22):e2201883119.
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Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 12; 74(6):3284-3300.
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Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana J, Seibold MA, Burchard EG. Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth. Am J Respir Crit Care Med. 2020 10 01; 202(7):962-972.
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Zukowski A, Rao S, Ramachandran S. Phenotypes from cell-free DNA. Open Biol. 2020 09; 10(9):200119.
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Upton K, Modi A, Patel K, Kendsersky NM, Conkrite KL, Sussman RT, Way GP, Adams RN, Sacks GI, Fortina P, Diskin SJ, Maris JM, Rokita JL. Epigenomic profiling of neuroblastoma cell lines. Sci Data. 2020 04 14; 7(1):116.
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Stern JL, Hibshman G, Hu K, Ferrara SE, Costello JC, Kim W, Tamayo P, Cech TR, Huang FW. Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Mol Cancer Res. 2020 07; 18(7):1050-1062.
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Greenwood J, Patel H, Cech TR, Cooper JP. Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA. Nucleic Acids Res. 2018 09 28; 46(17):8865-8875.
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Cardiello JF, Goodrich JA, Kugel JF. Heat Shock Causes a Reversible Increase in RNA Polymerase II Occupancy Downstream of mRNA Genes, Consistent with a Global Loss in Transcriptional Termination. Mol Cell Biol. 2018 09 15; 38(18).
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Tatavosian R, Ren X. Sm-ChIPi: Single-Molecule Chromatin Immunoprecipitation Imaging. Methods Mol Biol. 2018; 1689:113-126.
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Liu Y, Yu S, Dhiman VK, Brunetti T, Eckart H, White KP. Functional assessment of human enhancer activities using whole-genome STARR-sequencing. Genome Biol. 2017 Nov 20; 18(1):219.
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