 Chromatin Immunoprecipitation
"Chromatin Immunoprecipitation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technique for identifying specific DNA sequences that are bound, in vivo, to proteins of interest. It involves formaldehyde fixation of CHROMATIN to crosslink the DNA-BINDING PROTEINS to the DNA. After shearing the DNA into small fragments, specific DNA-protein complexes are isolated by immunoprecipitation with protein-specific ANTIBODIES. Then, the DNA isolated from the complex can be identified by PCR amplification and sequencing.
| Descriptor ID |
D047369
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| MeSH Number(s) |
E05.393.170 E05.478.605.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromatin Immunoprecipitation".
Below are MeSH descriptors whose meaning is more specific than "Chromatin Immunoprecipitation".
This graph shows the total number of publications written about "Chromatin Immunoprecipitation" by people in this website by year, and whether "Chromatin Immunoprecipitation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 5 | 6 | | 2007 | 0 | 6 | 6 | | 2008 | 0 | 5 | 5 | | 2009 | 1 | 6 | 7 | | 2010 | 0 | 8 | 8 | | 2011 | 1 | 14 | 15 | | 2012 | 0 | 8 | 8 | | 2013 | 2 | 11 | 13 | | 2014 | 0 | 3 | 3 | | 2015 | 0 | 9 | 9 | | 2016 | 1 | 8 | 9 | | 2017 | 1 | 5 | 6 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromatin Immunoprecipitation" by people in Profiles.
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Tatavosian R, Ren X. Sm-ChIPi: Single-Molecule Chromatin Immunoprecipitation Imaging. Methods Mol Biol. 2018; 1689:113-126.
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Brown DA, Di Cerbo V, Feldmann A, Ahn J, Ito S, Blackledge NP, Nakayama M, McClellan M, Dimitrova E, Turberfield AH, Long HK, King HW, Kriaucionis S, Schermelleh L, Kutateladze TG, Koseki H, Klose RJ. The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin. Cell Rep. 2017 Sep 05; 20(10):2313-2327.
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Sasse SK, Kadiyala V, Danhorn T, Panettieri RA, Phang TL, Gerber AN. Glucocorticoid Receptor ChIP-Seq Identifies PLCD1 as a KLF15 Target that Represses Airway Smooth Muscle Hypertrophy. Am J Respir Cell Mol Biol. 2017 08; 57(2):226-237.
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Helling BA, Gerber AN, Kadiyala V, Sasse SK, Pedersen BS, Sparks L, Nakano Y, Okamoto T, Evans CM, Yang IV, Schwartz DA. Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2017 07; 57(1):91-99.
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Lavender CA, Shapiro AJ, Burkholder AB, Bennett BD, Adelman K, Fargo DC. ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data. Nucleic Acids Res. 2017 Jun 02; 45(10):5678-5690.
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Rao D, Perraud AL, Schmitz C, Gally F. Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter. PLoS One. 2017; 12(5):e0178021.
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Kim YD, Hwang SL, Lee EJ, Kim HM, Chung MJ, Elfadl AK, Lee SE, Nedumaran B, Harris RA, Jeong KS. Melatonin ameliorates alcohol-induced bile acid synthesis by enhancing miR-497 expression. J Pineal Res. 2017 Mar; 62(2).
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Choi H, Ghosh D, Qin Z. Computationally Tractable Multivariate HMM in Genome-Wide Mapping Studies. Methods Mol Biol. 2017; 1552:135-148.
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Benam KH, Ingber DE. Commendation for Exposing Key Advantage of Organ Chip Approach. Cell Syst. 2016 11 23; 3(5):411.
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Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J, Chai Y. The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development. 2016 07 15; 143(14):2677-88.
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