 Interleukin-1beta
"Interleukin-1beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
| Descriptor ID |
D053583
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| MeSH Number(s) |
D12.644.276.374.465.010.600 D12.644.276.374.500.400.600 D12.776.467.374.465.010.600 D12.776.467.374.500.400.600 D23.529.374.465.131.600 D23.529.374.500.400.600
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| Concept/Terms |
Interleukin-1beta- Interleukin-1beta
- Interleukin 1beta
- IL-1 beta
- Interleukin-1 beta
- Interleukin 1 beta
- Catabolin
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1beta".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1beta".
This graph shows the total number of publications written about "Interleukin-1beta" by people in this website by year, and whether "Interleukin-1beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 2 | 4 | | 2007 | 10 | 3 | 13 | | 2008 | 5 | 5 | 10 | | 2009 | 11 | 6 | 17 | | 2010 | 8 | 6 | 14 | | 2011 | 9 | 17 | 26 | | 2012 | 9 | 8 | 17 | | 2013 | 10 | 10 | 20 | | 2014 | 8 | 12 | 20 | | 2015 | 2 | 10 | 12 | | 2016 | 2 | 8 | 10 | | 2017 | 2 | 9 | 11 | | 2018 | 4 | 11 | 15 | | 2019 | 2 | 9 | 11 | | 2020 | 1 | 8 | 9 | | 2021 | 4 | 4 | 8 | | 2023 | 1 | 0 | 1 | | 2024 | 0 | 4 | 4 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-1beta" by people in Profiles.
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Lippincott MJ, Tomkinson J, Bunten D, Mohammadi M, Kastl J, Knop J, Schwandner R, Huang J, Ongo G, Robichaud N, Dagher M, Mansilla-Soto A, Saravia-Estrada C, Tsuboi M, Basualto-Alarc?n C, Way GP. A morphology and secretome map of pyroptosis. Mol Biol Cell. 2025 Jun 01; 36(6):ar63.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fern?ndez-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 Apr; 640(8058):524-533.
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Amrute JM, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, Bredemeyer A, Jung IH, Kadyrov FF, Heo GS, Venkatesan R, Shi SY, Parvathaneni A, Koenig AL, Kuppe C, Baker C, Luehmann H, Jones C, Kopecky B, Zeng X, Bleckwehl T, Ma P, Lee P, Terada Y, Fu A, Furtado M, Kreisel D, Kovacs A, Stitziel NO, Jackson S, Li CM, Liu Y, Rosenthal NA, Kramann R, Ason B, Lavine KJ. Targeting immune-fibroblast cell communication in heart failure. Nature. 2024 Nov; 635(8038):423-433.
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Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Chromatin remodelling drives immune cell-fibroblast communication in heart failure. Nature. 2024 Nov; 635(8038):434-443.
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Tengesdal IW, Banks M, Dinarello CA, Marchetti C. Screening NLRP3 drug candidates in clinical development: lessons from existing and emerging technologies. Front Immunol. 2024; 15:1422249.
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Necker-Brown A, Kooi C, Thorne AJ, Bansal A, Mostafa MM, Chandramohan P, Gao A, Kalyanaraman K, Milani A, Gill S, Georgescu A, Sasse SK, Gerber AN, Leigh R, Newton R. Inducible gene expression of I?B-kinase e is dependent on nuclear factor-?B in human pulmonary epithelial cells. Biochem J. 2024 07 17; 481(14):959-980.
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Green-Fulgham SM, Ball JB, Kwilasz AJ, Harland ME, Frank MG, Dragavon JM, Grace PM, Watkins LR. Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats. Brain Behav Immun. 2024 01; 115:157-168.
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El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 02; 75(2):252-265.
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Tengesdal IW, Dinarello A, Powers NE, Burchill MA, Joosten LAB, Marchetti C, Dinarello CA. Tumor NLRP3-Derived IL-1? Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression. Front Immunol. 2021; 12:661323.
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Higa KC, Goodspeed A, Chavez JS, De Dominici M, Danis E, Zaberezhnyy V, Rabe JL, Tenen DG, Pietras EM, DeGregori J. Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. J Exp Med. 2021 06 07; 218(6).
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