 Sodium-Potassium-Exchanging ATPase
"Sodium-Potassium-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
| Descriptor ID |
D000254
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| MeSH Number(s) |
D08.811.277.040.025.314.750 D12.776.157.530.450.162.780 D12.776.157.530.450.250.880 D12.776.157.530.813.750 D12.776.543.585.450.162.800 D12.776.543.585.450.250.890 D12.776.543.585.813.750
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| Concept/Terms |
Sodium-Potassium-Exchanging ATPase- Sodium-Potassium-Exchanging ATPase
- ATPase, Sodium-Potassium-Exchanging
- Sodium Potassium Exchanging ATPase
- Sodium, Potassium Adenosinetriphosphatase
- Adenosinetriphosphatase Sodium, Potassium
- ATPase, Sodium, Potassium
- Sodium, Potassium ATPase
- ATPase Sodium, Potassium
- Potassium Pump
- Pump, Potassium
- Sodium, Potassium Adenosine Triphosphatase
- Sodium-Potassium Pump
- Pump, Sodium-Potassium
- Sodium Potassium Pump
- Na(+) K(+)-Transporting ATPase
- Na(+)-K(+)-Transporting ATPase
- Na(+)-K(+)-Exchanging ATPase
- Adenosine Triphosphatase, Sodium, Potassium
- Adenosinetriphosphatase, Sodium, Potassium
- Sodium Pump
- Pump, Sodium
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Below are MeSH descriptors whose meaning is more general than "Sodium-Potassium-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Potassium-Exchanging ATPase".
This graph shows the total number of publications written about "Sodium-Potassium-Exchanging ATPase" by people in this website by year, and whether "Sodium-Potassium-Exchanging ATPase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2008 | 1 | 2 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 3 | 0 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Potassium-Exchanging ATPase" by people in Profiles.
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Moya-Mendez ME, Bidzimou MT, Muralidharan P, Zhang Z, Ezekian JE, Perelli RM, Parker LE, Prange L, Boggs A, Kim JJ, Howard TS, Word TA, Wehrens XHT, Reyes Valenzuela G, Caraballo R, Garone G, Vigevano F, Weckhuysen S, Millevert C, Troncoso M, Matamala M, Balestrini S, Sisodiya SM, Poole J, Zucca C, Panagiotakaki E, Papadopoulou MT, Tchaicha S, Zawadzka M, Mazurkiewicz-Beldzinska M, Fons C, Anticona J, De Grandis E, Cordani R, Pisciotta L, Groppa S, Paryjas S, Ragona F, Mangia E, Granata T, Megvinov A, Pavlicek M, Ess K, Simmons CQ, George AL, Vavassori R, Mikati MA, Landstrom AP. ATP1A3 Variants, Variably Penetrant Short QT Intervals, and Lethal Ventricular Arrhythmias. JAMA Pediatr. 2025 May 01; 179(5):529-539.
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Springer CS, Baker EM, Li X, Moloney B, Pike MM, Wilson GJ, Anderson VC, Sammi MK, Garzotto MG, Kopp RP, Coakley FV, Rooney WD, Maki JH. Metabolic activity diffusion imaging (MADI): II. Noninvasive, high-resolution human brain mapping of sodium pump flux and cell metrics. NMR Biomed. 2023 01; 36(1):e4782.
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Morotti S, Ni H, Peters CH, Rickert C, Asgari-Targhi A, Sato D, Glukhov AV, Proenza C, Grandi E. Intracellular Na+ Modulates Pacemaking Activity in Murine Sinoatrial Node Myocytes: An In Silico Analysis. Int J Mol Sci. 2021 May 26; 22(11).
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Snow JP, Westlake G, Klofas LK, Jeon S, Armstrong LC, Swoboda KJ, George AL, Ess KC. Neuronal modeling of alternating hemiplegia of childhood reveals transcriptional compensation and replicates a trigger-induced phenotype. Neurobiol Dis. 2020 07; 141:104881.
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Arystarkhova E, Haq IU, Luebbert T, Mochel F, Saunders-Pullman R, Bressman SB, Feschenko P, Salazar C, Cook JF, Demarest S, Brashear A, Ozelius LJ, Sweadner KJ. Factors in the disease severity of ATP1A3 mutations: Impairment, misfolding, and allele competition. Neurobiol Dis. 2019 12; 132:104577.
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Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George AL. Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood. Neurobiol Dis. 2018 07; 115:29-38.
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Gritz SM, Larson C, Radcliffe RA. Atp1a2 contributes modestly to alcohol-related behaviors. Alcohol. 2016 11; 56:29-37.
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Yan Y, Shapiro AP, Mopidevi BR, Chaudhry MA, Maxwell K, Haller ST, Drummond CA, Kennedy DJ, Tian J, Malhotra D, Xie ZJ, Shapiro JI, Liu J. Protein Carbonylation of an Amino Acid Residue of the Na/K-ATPase a1 Subunit Determines Na/K-ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells. J Am Heart Assoc. 2016 09 09; 5(9).
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Ashbrook AW, Lentscher AJ, Zamora PF, Silva LA, May NA, Bauer JA, Morrison TE, Dermody TS. Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection. mBio. 2016 05 24; 7(3).
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McCabe KL, Kunzevitzky NJ, Chiswell BP, Xia X, Goldberg JL, Lanza R. Efficient Generation of Human Embryonic Stem Cell-Derived Corneal Endothelial Cells by Directed Differentiation. PLoS One. 2015; 10(12):e0145266.
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