 CDC2-CDC28 Kinases
"CDC2-CDC28 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CEREVISIAE; and the CDC2 PROTEIN KINASE found in mammalian species.
| Descriptor ID |
D042846
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| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500 D12.644.360.250.067 D12.776.167.200.067 D12.776.476.250.067
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| Concept/Terms |
CDC2-CDC28 Kinases- CDC2-CDC28 Kinases
- CDC2 CDC28 Kinases
- CDC2+-CDC28-related Protein Kinase
- CDC2+ CDC28 related Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "CDC2-CDC28 Kinases".
Below are MeSH descriptors whose meaning is more specific than "CDC2-CDC28 Kinases".
This graph shows the total number of publications written about "CDC2-CDC28 Kinases" by people in this website by year, and whether "CDC2-CDC28 Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 2 | 4 | | 2005 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "CDC2-CDC28 Kinases" by people in Profiles.
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Rong Y, Darnell AM, Sapp KM, Vander Heiden MG, Spencer SL. Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids. Cell Rep. 2023 12 26; 42(12):113539.
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Black JC, Zhang H, Kim J, Getz G, Whetstine JR. Regulation of Transient Site-specific Copy Gain by MicroRNA. J Biol Chem. 2016 Mar 04; 291(10):4862-71.
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Black JC, Atabakhsh E, Kim J, Biette KM, Van Rechem C, Ladd B, Burrowes PD, Donado C, Mattoo H, Kleinstiver BP, Song B, Andriani G, Joung JK, Iliopoulos O, Montagna C, Pillai S, Getz G, Whetstine JR. Hypoxia drives transient site-specific copy gain and drug-resistant gene expression. Genes Dev. 2015 May 15; 29(10):1018-31.
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Ungermannova D, Lee J, Zhang G, Dallmann HG, McHenry CS, Liu X. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1. J Biomol Screen. 2013 Sep; 18(8):910-20.
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Ungermannova D, Gao Y, Liu X. Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2. J Biol Chem. 2005 Aug 26; 280(34):30301-9.
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Wang W, Ungermannova D, Chen L, Liu X. Molecular and biochemical characterization of the Skp2-Cks1 binding interface. J Biol Chem. 2004 Dec 03; 279(49):51362-9.
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Agarwal C, Dhanalakshmi S, Singh RP, Agarwal R. Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells. Neoplasia. 2004 Sep-Oct; 6(5):646-59.
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Su TT, Stumpff J. Promiscuity rules? The dispensability of cyclin E and Cdk2. Sci STKE. 2004 Mar 09; 2004(224):pe11.
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Wang W, Ungermannova D, Jin J, Harper JW, Liu X. Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling. Oncogene. 2004 Feb 05; 23(5):1064-75.
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Cook JG, Park CH, Burke TW, Leone G, DeGregori J, Engel A, Nevins JR. Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1347-52.
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