 Cyclin-Dependent Kinase 5
"Cyclin-Dependent Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CELL DEATH of NERVE CELLS. It is closely related to other CYCLIN-DEPENDENT KINASES but does not seem to participate in CELL CYCLE regulation.
| Descriptor ID |
D051360
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| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500.500 D12.644.360.250.067.875 D12.776.167.200.067.875 D12.776.476.250.067.875
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| Concept/Terms |
Cyclin-Dependent Kinase 5- Cyclin-Dependent Kinase 5
- Cyclin Dependent Kinase 5
- Neuronal Cdc2-Like Protein Kinase
- Neuronal Cdc2 Like Protein Kinase
- Cdk5 Protein Kinase
- Protein Kinase, Cdk5
- Cdk5 Protein
- PSSALRE Protein
- Cdc2-Related Kinase PSSALRE
- Cdc2 Related Kinase PSSALRE
- PSSALRE, Cdc2-Related Kinase
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Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 5".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase 5" by people in this website by year, and whether "Cyclin-Dependent Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase 5" by people in Profiles.
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Bastian C, Quinn J, Tripathi A, Aquila D, McCray A, Dutta R, Baltan S, Brunet S. CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the CDK5 and AKT signaling pathways. Neurobiol Dis. 2019 06; 126:47-61.
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Mitra A, Mitra SS, Tsien RW. Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity. Nat Neurosci. 2011 Dec 18; 15(2):250-7.
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Teegarden SL, Scott AN, Bale TL. Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling. Neuroscience. 2009 Sep 15; 162(4):924-32.
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Teegarden SL, Nestler EJ, Bale TL. Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biol Psychiatry. 2008 Dec 01; 64(11):941-50.
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Wu HY, Lynch DR. Calpain and synaptic function. Mol Neurobiol. 2006 Jun; 33(3):215-36.
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Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF. Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19; 46(4):569-79.
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