S-Adenosylhomocysteine
"S-Adenosylhomocysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Descriptor ID |
D012435
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MeSH Number(s) |
D02.886.030.498.050 D03.633.100.759.590.138.240 D12.125.166.498.050 D13.570.583.138.240 D13.570.800.096.262
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "S-Adenosylhomocysteine".
Below are MeSH descriptors whose meaning is more specific than "S-Adenosylhomocysteine".
This graph shows the total number of publications written about "S-Adenosylhomocysteine" by people in this website by year, and whether "S-Adenosylhomocysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 2003 | 1 | 1 | 2 | 2004 | 1 | 1 | 2 | 2005 | 1 | 0 | 1 | 2006 | 1 | 1 | 2 | 2007 | 3 | 1 | 4 | 2008 | 0 | 2 | 2 | 2009 | 1 | 1 | 2 | 2010 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "S-Adenosylhomocysteine" by people in Profiles.
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Stabler SP. Alterations in Sulfur Amino Acids as Biomarkers of Disease. J Nutr. 2020 10 01; 150(Suppl 1):2532S-2537S.
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Osna NA, Feng D, Ganesan M, Maillacheruvu PF, Orlicky DJ, French SW, Tuma DJ, Kharbanda KK. Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury. World J Gastroenterol. 2016 Oct 14; 22(38):8497-8508.
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Kharbanda KK, Todero SL, Thomes PG, Orlicky DJ, Osna NA, French SW, Tuma DJ. Increased methylation demand exacerbates ethanol-induced liver injury. Exp Mol Pathol. 2014 Aug; 97(1):49-56.
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Klepacki J, Brunner N, Schmitz V, Klawitter J, Christians U, Klawitter J. Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma. Clin Chim Acta. 2013 Jun 05; 421:91-7.
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Benight NM, Stoll B, Chacko S, da Silva VR, Marini JC, Gregory JF, Stabler SP, Burrin DG. B-vitamin deficiency is protective against DSS-induced colitis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G249-59.
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Edwards AL, Reyes FE, H?roux A, Batey RT. Structural basis for recognition of S-adenosylhomocysteine by riboswitches. RNA. 2010 Nov; 16(11):2144-55.
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Montange RK, Mondrag?n E, van Tyne D, Garst AD, Ceres P, Batey RT. Discrimination between closely related cellular metabolites by the SAM-I riboswitch. J Mol Biol. 2010 Feb 26; 396(3):761-72.
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Stabler SP, Sekhar J, Allen RH, O'Neill HC, White CW. Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med. 2009 Oct 15; 47(8):1147-53.
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Panayiotidis MI, Stabler SP, Allen RH, Pappa A, White CW. Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells. Mutat Res. 2009 Mar 31; 674(1-2):23-30.
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Lopreato FR, Stabler SP, Carvalho FR, Hirata RD, Hirata MH, Robi DL, Sampaio-Neto LF, Allen RH, Guerra-Shinohara EM. Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. Clin Chim Acta. 2008 Dec; 398(1-2):134-9.
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