 Dual Specificity Phosphatase 6
"Dual Specificity Phosphatase 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CYTOSOL.
| Descriptor ID |
D054642
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| MeSH Number(s) |
D08.811.277.352.650.587.600 D08.811.277.352.650.625.225.600 D08.811.277.352.650.775.250.600 D08.811.641.755.600 D12.644.360.268.600 D12.644.360.445.600 D12.776.476.268.600 D12.776.476.445.600
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| Concept/Terms |
Dual Specificity Phosphatase 6- Dual Specificity Phosphatase 6
- Dual Specificity Protein Phosphatase 6
- MKP-3 Phosphatase
- MKP 3 Phosphatase
- Phosphatase, MKP-3
- MKP3 Phosphatase
- Phosphatase, MKP3
- MAP Kinase Phosphatase 3
- Mitogen-Activated Protein Kinase Phosphatase 3
- Mitogen Activated Protein Kinase Phosphatase 3
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Below are MeSH descriptors whose meaning is more general than "Dual Specificity Phosphatase 6".
Below are MeSH descriptors whose meaning is more specific than "Dual Specificity Phosphatase 6".
This graph shows the total number of publications written about "Dual Specificity Phosphatase 6" by people in this website by year, and whether "Dual Specificity Phosphatase 6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dual Specificity Phosphatase 6" by people in Profiles.
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Maurer JM, Sagerstr?m CG. A parental requirement for dual-specificity phosphatase 6 in zebrafish. BMC Dev Biol. 2018 03 15; 18(1):6.
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Kumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal C. Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. Mol Carcinog. 2018 Jan; 57(1):57-69.
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Hrustanovic G, Olivas V, Pazarentzos E, Tulpule A, Asthana S, Blakely CM, Okimoto RA, Lin L, Neel DS, Sabnis A, Flanagan J, Chan E, Varella-Garcia M, Aisner DL, Vaishnavi A, Ou SH, Collisson EA, Ichihara E, Mack PC, Lovly CM, Karachaliou N, Rosell R, Riess JW, Doebele RC, Bivona TG. RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer. Nat Med. 2015 Sep; 21(9):1038-47.
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Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N. Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet. 2013 May 02; 92(5):725-43.
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