 PrPSc Proteins
"PrPSc Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
| Descriptor ID |
D018620
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| MeSH Number(s) |
D12.776.785.340.750
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| Concept/Terms |
PrPSc Proteins- PrPSc Proteins
- Scrapie PrP 33-35
- PrP-res
- PrP res
- Sp 33-35
- Scrapie PrP
- PrP 33-35
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Below are MeSH descriptors whose meaning is more general than "PrPSc Proteins".
Below are MeSH descriptors whose meaning is more specific than "PrPSc Proteins".
This graph shows the total number of publications written about "PrPSc Proteins" by people in this website by year, and whether "PrPSc Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "PrPSc Proteins" by people in Profiles.
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Groveman BR, Kraus A, Raymond LD, Dolan MA, Anson KJ, Dorward DW, Caughey B. Charge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids. J Biol Chem. 2015 Jan 09; 290(2):1119-28.
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Pulford B, Spraker TR, Wyckoff AC, Meyerett C, Bender H, Ferguson A, Wyatt B, Lockwood K, Powers J, Telling GC, Wild MA, Zabel MD. Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification. J Wildl Dis. 2012 Apr; 48(2):425-34.
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Bosque P. Molecular types of Creutzfeldt-Jakob disease: the strange diversity of prions. Neurology. 2005 Nov 22; 65(10):1520-1.
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Tyler KL. COMMENTARY: Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC. Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J Infect Dis 1980; 142:205-208. J Infect Dis. 2004 Aug 01; 190(3):653-60.
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Tyler KL. Creutzfeldt-Jakob disease. N Engl J Med. 2003 Feb 20; 348(8):681-2.
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Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. Prions in skeletal muscle. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3812-7.
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