 Prion Proteins
"Prion Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
| Descriptor ID |
D000072002
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| MeSH Number(s) |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340
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| Concept/Terms |
Prion Proteins- Prion Proteins
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- PrP Proteins
- Fatal Familial Insomnia Protein
- Major Prion Protein
- Prion Protein, Major
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
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Below are MeSH descriptors whose meaning is more general than "Prion Proteins".
Below are MeSH descriptors whose meaning is more specific than "Prion Proteins".
This graph shows the total number of publications written about "Prion Proteins" by people in this website by year, and whether "Prion Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prion Proteins" by people in Profiles.
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Thackray AM, Lam B, McNulty EE, Nalls AV, Mathiason CK, Magadi SS, Jackson WS, Andr?oletti O, Marrero-Winkens C, Sch?tzl H, Bujdoso R. Clearance of variant Creutzfeldt-Jakob disease prions in vivo by the Hsp70 disaggregase system. Brain. 2022 09 14; 145(9):3236-3249.
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Chafin TK, Douglas MR, Martin BT, Zbinden ZD, Middaugh CR, Ballard JR, Gray MC, Douglas ME. Age structuring and spatial heterogeneity in prion protein gene (PRNP) polymorphism in white-tailed deer. Prion. 2020 12; 14(1):238-248.
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Henderson DM, Denkers ND, Hoover CE, McNulty EE, Cooper SK, Bracchi LA, Mathiason CK, Hoover EA. Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry. PLoS One. 2020; 15(2):e0228327.
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Rovnak J, St Clair LA, Lian E, McAlister C, Perera R, Cohrs RJ. The 19th Rocky Mountain Virology Association Meeting. Viruses. 2020 01 11; 12(1).
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McNulty E, Nalls AV, Mellentine S, Hughes E, Pulscher L, Hoover EA, Mathiason CK. Comparison of conventional, amplification and bio-assay detection methods for a chronic wasting disease inoculum pool. PLoS One. 2019; 14(5):e0216621.
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Rovnak J, Clair LAS, Krieger K, Lian E, Perera R, Cohrs RJ. The 18th Rocky Mountain Virology Association Meeting. Viruses. 2018 12 21; 11(1).
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Bender HR, Kane S, Zabel MD. Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes. J Vis Exp. 2016 07 23; (113).
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Chadwick LH, McCandless SE, Silverman GL, Schwartz S, Westaway D, Nadeau JH. Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes. Genomics. 2000 Nov 15; 70(1):66-73.
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