Wasting Disease, Chronic
"Wasting Disease, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmissible spongiform encephalopathy (prion disease) of DEER and elk characterized by chronic weight loss leading to death. It is thought to spread by direct contact between animals or through environmental contamination with the prion protein (PRIONS).
Descriptor ID |
D034081
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MeSH Number(s) |
C10.228.228.800.858 C10.574.843.925 C22.955
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wasting Disease, Chronic".
Below are MeSH descriptors whose meaning is more specific than "Wasting Disease, Chronic".
This graph shows the total number of publications written about "Wasting Disease, Chronic" by people in this website by year, and whether "Wasting Disease, Chronic" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 2 | 0 | 2 | 2007 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2017 | 2 | 0 | 2 | 2019 | 1 | 0 | 1 | 2020 | 3 | 0 | 3 | 2021 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wasting Disease, Chronic" by people in Profiles.
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Thackray AM, McNulty EE, Nalls AV, Cardova A, Tran L, Telling G, Benestad SL, Gilch S, Mathiason CK, Bujdoso R. Genetic modulation of CWD prion propagation in cervid PrP Drosophila. Biochem J. 2023 10 11; 480(19):1485-1501.
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Nalls AV, McNulty EE, Mayfield A, Crum JM, Keel MK, Hoover EA, Ruder MG, Mathiason CK. Detection of Chronic Wasting Disease Prions in Fetal Tissues of Free-Ranging White-Tailed Deer. Viruses. 2021 12 03; 13(12).
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Denkers ND, Hoover CE, Davenport KA, Henderson DM, McNulty EE, Nalls AV, Mathiason CK, Hoover EA. Very low oral exposure to prions of brain or saliva origin can transmit chronic wasting disease. PLoS One. 2020; 15(8):e0237410.
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McNulty EE, Nalls AV, Xun R, Denkers ND, Hoover EA, Mathiason CK. In vitro detection of haematogenous prions in white-tailed deer orally dosed with low concentrations of chronic wasting disease. J Gen Virol. 2020 03; 101(3):347-361.
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Henderson DM, Denkers ND, Hoover CE, McNulty EE, Cooper SK, Bracchi LA, Mathiason CK, Hoover EA. Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry. PLoS One. 2020; 15(2):e0228327.
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McNulty E, Nalls AV, Mellentine S, Hughes E, Pulscher L, Hoover EA, Mathiason CK. Comparison of conventional, amplification and bio-assay detection methods for a chronic wasting disease inoculum pool. PLoS One. 2019; 14(5):e0216621.
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Davenport KA, Mosher BA, Brost BM, Henderson DM, Denkers ND, Nalls AV, McNulty E, Mathiason CK, Hoover EA. Assessment of Chronic Wasting Disease Prion Shedding in Deer Saliva with Occupancy Modeling. J Clin Microbiol. 2018 01; 56(1).
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Nalls AV, McNulty E, Hoover CE, Pulscher LA, Hoover EA, Mathiason CK. Infectious Prions in the Pregnancy Microenvironment of Chronic Wasting Disease-Infected Reeves' Muntjac Deer. J Virol. 2017 08 01; 91(15).
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McNulty E, Selariu AI, Anderson K, Hayes-Klug J, Nalls AV, Powers JG, Hoover EA, Mathiason CK. Aspects of the husbandry and management of captive cervids. Lab Anim (NY). 2016 Apr; 45(4):140-2.
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Michel B, Ferguson A, Johnson T, Bender H, Meyerett-Reid C, Wyckoff AC, Pulford B, Telling GC, Zabel MD. Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease. Int Immunol. 2013 Dec; 25(12):697-702.
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