 Core Binding Factor Alpha 3 Subunit
"Core Binding Factor Alpha 3 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain.
| Descriptor ID |
D050677
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| MeSH Number(s) |
D12.776.930.155.200.300
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| Concept/Terms |
Core Binding Factor Alpha 3 Subunit- Core Binding Factor Alpha 3 Subunit
- AML2 Protein
- CBFA3 Protein
- Runx3 Protein
- PEBP2A3 Protein
- Runt Domain Transcription Factor AML-2
- Runt-Related Transcription Factor 3 Protein
- Runt Related Transcription Factor 3 Protein
- Acute Myeloid Leukemia 2 Protein
- Core-Binding Factor Alpha 3 Protein
- Core Binding Factor Alpha 3 Protein
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Below are MeSH descriptors whose meaning is more general than "Core Binding Factor Alpha 3 Subunit".
Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor Alpha 3 Subunit".
This graph shows the total number of publications written about "Core Binding Factor Alpha 3 Subunit" by people in this website by year, and whether "Core Binding Factor Alpha 3 Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Core Binding Factor Alpha 3 Subunit" by people in Profiles.
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Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul; 136(1):69-80.
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Wang M, Gelfand EW. Targeting Pim1 kinase in the treatment of peanut allergy. Expert Opin Ther Targets. 2014 Feb; 18(2):177-83.
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Wang M, Okamoto M, Domenico J, Han J, Ashino S, Shin YS, Gelfand EW. Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation. J Allergy Clin Immunol. 2012 Oct; 130(4):932-44.e12.
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Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H. Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug; 22(8):1260-70.
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