 Core Binding Factor alpha Subunits
"Core Binding Factor alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
| Descriptor ID |
D050657
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| MeSH Number(s) |
D12.776.930.155.200
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| Concept/Terms |
Core Binding Factor alpha Subunits- Core Binding Factor alpha Subunits
- Core Binding Factor alpha Proteins
- Runx Proteins
- Polyomavirus Enhancer A Binding Protein 2
- Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
- Runt Domain Factor
- Acute Myeloid Leukemia Proteins
- PEBP2A Transcription Factors
- Transcription Factors, PEBP2A
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Below are MeSH descriptors whose meaning is more general than "Core Binding Factor alpha Subunits".
Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor alpha Subunits".
This graph shows the total number of publications written about "Core Binding Factor alpha Subunits" by people in this website by year, and whether "Core Binding Factor alpha Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Core Binding Factor alpha Subunits" by people in Profiles.
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Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudi?re-Morrison L, Mercier AL, Shokouhian M, Su?rez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, B?rub? P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, F?vre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, L?pez-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Egu?a P, P?rezpe?a M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 09; 609(7929):1021-1028.
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