 Wilms Tumor
"Wilms Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Descriptor ID |
D009396
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| MeSH Number(s) |
C04.557.435.595 C04.588.945.947.535.585 C04.700.635 C12.758.820.750.585 C12.777.419.473.585 C13.351.937.820.535.585 C13.351.968.419.473.585 C16.320.700.642
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| Concept/Terms |
Wilms Tumor- Wilms Tumor
- Tumor, Wilms
- Wilms' Tumor
- Tumor, Wilms'
- Wilm Tumor
- Wilm's Tumor
- Wilms Tumor 1
- Nephroblastoma
- Nephroblastomas
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Below are MeSH descriptors whose meaning is more general than "Wilms Tumor".
Below are MeSH descriptors whose meaning is more specific than "Wilms Tumor".
This graph shows the total number of publications written about "Wilms Tumor" by people in this website by year, and whether "Wilms Tumor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 3 | 0 | 3 | | 2012 | 3 | 0 | 3 | | 2013 | 2 | 1 | 3 | | 2014 | 3 | 0 | 3 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 2 | 2 | | 2017 | 5 | 2 | 7 | | 2018 | 5 | 0 | 5 | | 2019 | 9 | 1 | 10 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 4 | 0 | 4 | | 2023 | 5 | 0 | 5 | | 2024 | 4 | 0 | 4 | | 2025 | 7 | 1 | 8 |
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Below are the most recent publications written about "Wilms Tumor" by people in Profiles.
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Groisser A, Frantz A, Geller JI, Ortiz MV, Walterhouse D, Ranalli M, Woods-Swafford W, Schoettler P, Garrington T, Mullen EA, Ash S, Bardhan P, Balis F, Dome JS. Anti-Tumor Activity of Paclitaxel-Containing Regimens in Recurrent/Refractory Wilms Tumor. Pediatr Blood Cancer. 2025 Oct; 72(10):e31915.
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Benedetti DJ, Cost NG, Ehrlich PF, Evageliou N, Fialkowski E, Parsons LN, Vallance KL, Renfro LA, Hong AL, Aldrink JH, Pater L, Paulino AC, Sandberg JK, Smith EA, Treece AL, Dome JS, Geller JI, Mullen EA. Updated favourable-histology Wilms tumour risk stratification: rationale for future Children's Oncology Group clinical trials. Nat Rev Urol. 2025 Nov; 22(11):775-788.
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van Peer SE, Treger TD, Wegert J, Hol JA, Le Gall J, Jakkula EE, Kamihara J, Mullen EA, Graf N, Behjati S, Al-Saadi R, Duncan C, Schienda J, de Putter R, Brzezinski J, Verschuur A, Michaeli O, Ortiz MV, Herkert JC, Armstrong R, Waanders E, Kuiper RP, van den Heuvel-Eibrink MM, Gessler M, Jongmans MCJ. Wilms tumor characteristics in children with heterozygous germline DIS3L2 variants. Genet Med. 2025 Sep; 27(9):101478.
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Campwala I, Schienda J, Murphy AJ, Hashimi B, Perry T, Cost N, Kamihara J, Mullen EA, Santiago T, Malek MM. Wilms Tumor in Children With AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series. Pediatr Blood Cancer. 2025 Aug; 72(8):e31798.
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Pio L, Bruno T, Godzinski J, Ehrlich PF, Cost N, Davidoff AM, Irtan S, Pachl M, Abu-Zaid A, Abdelhafeez AH, Losty PD. Comparison of open and minimally invasive nephrectomy for Wilms tumor: a systematic review and meta-analysis from the International Society of Pediatric Surgical Oncology. Pediatr Surg Int. 2025 Apr 16; 41(1):117.
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Acker SN, Ziogas IA, Cost N, Cooper E, Farooqui Z, Eason CR, Vaughn AE, Dawson-Gore C, Somers KM, Fineman SL, Vangi S, Carter MM, Hartman SJ, Kotagal M. Association of Systemic Inflammatory Markers and Clinical Outcomes Among Children With Wilms Tumor. Pediatr Blood Cancer. 2025 Jul; 72(7):e31715.
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Valverde P, Velasquez T, Ortiz R, Fuentes-Alabi SL, Peña A, Gonzalez JF, Gutierrez TL, Melendez LE, Tome E, Arreola M, Valsecchi MG, Colombo V, Luna-Fineman S, Blanco-Lopez J, Metzger ML, Spreafico F. Challenges and Opportunities of a Multi-Institutional Treatment Guideline for Wilms Tumor in Low-Middle-Income Countries-A Report From the Asociación de Hemato-Oncología Pediátrica de Centro América (AHOPCA). Pediatr Blood Cancer. 2025 May; 72(5):e31616.
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Perotti D, O'Sullivan MJ, Walz AL, Davick J, Al-Saadi R, Benedetti DJ, Brzezinski J, Ciceri S, Cost NG, Dome JS, Drost J, Evageliou N, Furtwängler R, Graf N, Maschietto M, Mullen EA, Murphy AJ, Ortiz MV, van der Beek JN, Verschuur A, Wegert J, Williams R, Spreafico F, Geller JI, van den Heuvel-Eibrink MM, Hong AL. Hallmark discoveries in the biology of non-Wilms tumour childhood kidney cancers. Nat Rev Urol. 2025 Aug; 22(8):526-543.
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Murphy AJ, Brzezinski J, Renfro LA, Tornwall B, Malek MM, Benedetti DJ, Cost NG, Smith EA, Aldrink J, Romao RLP, Dome JS, Davidoff AM, Treece AL, Parsons LN, Mullen EA, Shamberger RC, Paulino AC, Lo AC, Geller JI, Ehrlich PF. Long-term outcomes and patterns of relapse in patients with bilateral Wilms tumor or bilaterally predisposed unilateral Wilms tumor, a report from the COG AREN0534 study. Int J Cancer. 2024 Nov 15; 155(10):1824-1831.
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Romao RLP, Aldrink JH, Renfro LA, Mullen EA, Murphy AJ, Brzezinski J, Malek MM, Benedetti DJ, Cost NG, Smith E, Dome JS, Davidoff AM, Treece A, Parsons LN, Fernandez CV, Tornwall B, Shamberger RC, Paulino A, Kalapurakal JA, Geller JI, Ehrlich PF. Bilateral Wilms tumor with anaplasia: A report from the Children's Oncology Group Study AREN0534. Pediatr Blood Cancer. 2024 Jul; 71(7):e30981.
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