 Peptidoglycan
"Peptidoglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structural polymer of the bacterial cell envelope consisting of sugars and amino acids which is responsible for both shape determination and cellular integrity under osmotic stress in virtually all bacteria.
| Descriptor ID |
D010457
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| MeSH Number(s) |
D09.400.420.700 D09.698.718.594 D12.644.233.594 D12.776.395.560.800 D23.050.161.616.594
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptidoglycan".
Below are MeSH descriptors whose meaning is more specific than "Peptidoglycan".
This graph shows the total number of publications written about "Peptidoglycan" by people in this website by year, and whether "Peptidoglycan" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Peptidoglycan" by people in Profiles.
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Parrett GA, Brones PD, Jenkins GM, Mounts SM, Nguyen A, Risser DD. Identification of a morphogene required for tapered filament termini in filamentous cyanobacteria. Microbiology (Reading). 2023 11; 169(11).
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Wohlfarth JC, Feldm?ller M, Schneller A, Kilcher S, Burkolter M, Meile S, Pilhofer M, Schuppler M, Loessner MJ. L-form conversion in Gram-positive bacteria enables escape from phage infection. Nat Microbiol. 2023 03; 8(3):387-399.
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Tian D, Han M. Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists. Dev Cell. 2022 02 07; 57(3):361-372.e5.
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Nguyen DC, Dousa KM, Kurz SG, Brown ST, Drusano G, Holland SM, Kreiswirth BN, Boom WH, Daley CL, Bonomo RA. "One-Two Punch": Synergistic ?-Lactam Combinations for Mycobacterium abscessus and Target Redundancy in the Inhibition of Peptidoglycan Synthesis Enzymes. Clin Infect Dis. 2021 10 20; 73(8):1532-1536.
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Sobieraj AM, Huemer M, Zinsli LV, Meile S, Keller AP, R?hrig C, Eichenseher F, Shen Y, Zinkernagel AS, Loessner MJ, Schmelcher M. Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection. mBio. 2020 09 22; 11(5).
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Kuss-Duerkop SK, Keestra-Gounder AM. NOD1 and NOD2 Activation by Diverse Stimuli: a Possible Role for Sensing Pathogen-Induced Endoplasmic Reticulum Stress. Infect Immun. 2020 06 22; 88(7).
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Liang H, Zhou G, Ge Y, D'Ambrosio EA, Eidem TM, Blanchard C, Shehatou C, Chatare VK, Dunman PM, Valentine AM, Voelz VA, Grimes CL, Andrade RB. Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus. Bioorg Med Chem. 2018 07 23; 26(12):3453-3460.
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Keestra-Gounder AM, Tsolis RM. NOD1 and NOD2: Beyond Peptidoglycan Sensing. Trends Immunol. 2017 10; 38(10):758-767.
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Verbree CT, D?twyler SM, Meile S, Eichenseher F, Donovan DM, Loessner MJ, Schmelcher M. Identification of Peptidoglycan Hydrolase Constructs with Synergistic Staphylolytic Activity in Cow's Milk. Appl Environ Microbiol. 2017 04 01; 83(7).
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Keestra AM, Winter MG, Auburger JJ, Fr?ssle SP, Xavier MN, Winter SE, Kim A, Poon V, Ravesloot MM, Waldenmaier JF, Tsolis RM, Eigenheer RA, B?umler AJ. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature. 2013 Apr 11; 496(7444):233-7.
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