 Acyl Carrier Protein
"Acyl Carrier Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Consists of a polypeptide chain and 4'-phosphopantetheine linked to a serine residue by a phosphodiester bond. Acyl groups are bound as thiol esters to the pantothenyl group. Acyl carrier protein is involved in every step of fatty acid synthesis by the cytoplasmic system.
| Descriptor ID |
D000213
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| MeSH Number(s) |
D12.776.157.050
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acyl Carrier Protein".
Below are MeSH descriptors whose meaning is more specific than "Acyl Carrier Protein".
This graph shows the total number of publications written about "Acyl Carrier Protein" by people in this website by year, and whether "Acyl Carrier Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acyl Carrier Protein" by people in Profiles.
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Andrzejewski SJ, Friedman AJ, Mains K, Thompson A, Hamel NL, Sankaran B, Zwart PH, Shirts MR, Fox JM. Protein-Protein Complex Stability Controls Substrate Scope in a ß-Ketoacyl-ACP Reductase Specific for Medium Chains. Angew Chem Int Ed Engl. 2025 Sep 26; 64(40):e202508316.
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Gutka HJ, Bondoc JMG, Patwell R, Khan S, Grzelak EM, Goswami R, Voskuil MI, Movahedzadeh F. Rv0100: An essential acyl carrier protein from M. tuberculosis important in dormancy. PLoS One. 2024; 19(6):e0304876.
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Cai K, Frederick RO, Dashti H, Markley JL. Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering. Structure. 2018 08 07; 26(8):1127-1136.e4.
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Cai K, Frederick RO, Tonelli M, Markley JL. Mitochondrial Cysteine Desulfurase and ISD11 Coexpressed in Escherichia coli Yield Complex Containing Acyl Carrier Protein. ACS Chem Biol. 2017 04 21; 12(4):918-921.
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Cai K, Tonelli M, Frederick RO, Markley JL. Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis. Biochemistry. 2017 01 24; 56(3):487-499.
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Collins JM, Porter KA, Singh SK, Vanier GS. High-efficiency solid phase peptide synthesis (HE-SPPS). Org Lett. 2014 Feb 07; 16(3):940-3.
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Busche A, Gottstein D, Hein C, Ripin N, Pader I, Tufar P, Eisman EB, Gu L, Walsh CT, Sherman DH, L?hr F, G?ntert P, D?tsch V. Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase. ACS Chem Biol. 2012 Feb 17; 7(2):378-86.
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Zornetzer GA, White RD, Markley JL, Fox BG. Preparation of isotopically labeled spinach acyl-acyl carrier protein for NMR structural studies. Protein Expr Purif. 2006 Apr; 46(2):446-55.
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Gould TA, Schweizer HP, Churchill ME. Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI. Mol Microbiol. 2004 Aug; 53(4):1135-46.
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