Vitamin D-Binding Protein
"Vitamin D-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.
Descriptor ID |
D014809
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MeSH Number(s) |
D12.776.157.920
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Concept/Terms |
Vitamin D-Binding Protein- Vitamin D-Binding Protein
- Vitamin D Binding Protein
- 25-Hydroxycholecalciferol-Binding Protein
- 25 Hydroxycholecalciferol Binding Protein
- 25-Hydroxyvitamin D-Binding Protein
- 25 Hydroxyvitamin D Binding Protein
- Vitamin D-Binding Globulin
- Globulin, Vitamin D-Binding
- Vitamin D Binding Globulin
- Gc Globulin
- Globulin, Gc
- Group-Specific Component Globulin
- Component Globulin, Group-Specific
- Globulin, Group-Specific Component
- Group Specific Component Globulin
- Transcalciferin
- 25-HCC-Binding Protein
- 25 HCC Binding Protein
- Calciferol-Binding Protein
- Calciferol Binding Protein
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Below are MeSH descriptors whose meaning is more general than "Vitamin D-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "Vitamin D-Binding Protein".
This graph shows the total number of publications written about "Vitamin D-Binding Protein" by people in this website by year, and whether "Vitamin D-Binding Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2016 | 1 | 1 | 2 | 2018 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vitamin D-Binding Protein" by people in Profiles.
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Palmer ND, Lu L, Register TC, Lenchik L, Carr JJ, Hicks PJ, Smith SC, Xu J, Dimitrov L, Keaton J, Guan M, Ng MCY, Chen YI, Hanley AJ, Engelman CD, Norris JM, Langefeld CD, Wagenknecht LE, Bowden DW, Freedman BI, Divers J. Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. PLoS One. 2021; 16(5):e0251423.
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Kelly CB, Wagner CL, Shary JR, Leyva MJ, Yu JY, Jenkins AJ, Nankervis AJ, Hanssen KF, Garg SK, Scardo JA, Hammad SM, Aston CE, Lyons TJ. Vitamin D Metabolites and Binding Protein Predict Preeclampsia in Women with Type 1 Diabetes. Nutrients. 2020 Jul 10; 12(7).
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Jovanovich A, Kendrick J. Personalized Management of Bone and Mineral Disorders and Precision Medicine in End-Stage Kidney Disease. Semin Nephrol. 2018 07; 38(4):397-409.
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Young KA, Munroe ME, Guthridge JM, Kamen DL, Niewold TB, Gilkeson GS, Weisman MH, Ishimori ML, Kelly J, Gaffney PM, Sivils KH, Lu R, Wallace DJ, Karp DR, Harley JB, James JA, Norris JM. Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis. 2017 Jan; 76(1):153-158.
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Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Schepmoes AA, Zmuda JM, Lapidus J, Cauley JA, Bouillon R, Schoenmakers I, Orwoll ES. Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations. J Clin Endocrinol Metab. 2016 05; 101(5):2226-34.
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Havens PL, Kiser JJ, Stephensen CB, Hazra R, Flynn PM, Wilson CM, Rutledge B, Bethel J, Pan CG, Woodhouse LR, Van Loan MD, Liu N, Lujan-Zilbermann J, Baker A, Kapogiannis BG, Gordon CM, Mulligan K. Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency? Antimicrob Agents Chemother. 2013 Nov; 57(11):5619-28.
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Young KA, Snell-Bergeon JK, Naik RG, Hokanson JE, Tarullo D, Gottlieb PA, Garg SK, Rewers M. Vitamin D deficiency and coronary artery calcification in subjects with type 1 diabetes. Diabetes Care. 2011 Feb; 34(2):454-8.
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Bakke PS, Zhu G, Gulsvik A, Kong X, Agusti AG, Calverley PM, Donner CF, Levy RD, Make BJ, Par? PD, Rennard SI, Vestbo J, Wouters EF, Anderson W, Lomas DA, Silverman EK, Pillai SG. Candidate genes for COPD in two large data sets. Eur Respir J. 2011 Feb; 37(2):255-63.
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Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, Wagenknecht LE, Bowden DW, Norris JM. Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans. J Clin Endocrinol Metab. 2008 Sep; 93(9):3381-8.
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Iyengar S, Hamman RF, Marshall JA, Majumder PP, Ferrell RE. On the role of vitamin D binding globulin in glucose homeostasis: results from the San Luis Valley Diabetes Study. Genet Epidemiol. 1989; 6(6):691-8.
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