 5' Untranslated Regions
"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
| Descriptor ID |
D020121
|
| MeSH Number(s) |
D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
|
| Concept/Terms |
5' Untranslated Regions- 5' Untranslated Regions
- 5' Untranslated Region
- Region, 5' Untranslated
- Regions, 5' Untranslated
- Untranslated Region, 5'
- Untranslated Regions, 5'
- 5'UTR
- 5'UTRs
- Leader Sequences, mRNA
- Leader Sequence, mRNA
- Sequence, mRNA Leader
- Sequences, mRNA Leader
- mRNA Leader Sequence
- mRNA Leader Sequences
- 5' UTR
- 5' UTRs
- UTR, 5'
- UTRs, 5'
- Leader mRNA Sequences
- Leader mRNA Sequence
- Sequence, Leader mRNA
- Sequences, Leader mRNA
- mRNA Sequence, Leader
- mRNA Sequences, Leader
|
Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".
This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 2 | 3 | | 2002 | 0 | 1 | 1 | | 2004 | 2 | 3 | 5 | | 2005 | 1 | 1 | 2 | | 2006 | 5 | 2 | 7 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 3 | 4 | | 2010 | 2 | 2 | 4 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 | | 2022 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.
-
May GE, Akirtava C, Agar-Johnson M, Micic J, Woolford J, McManus J. Unraveling the influences of sequence and position on yeast uORF activity using massively parallel reporter systems and machine learning. Elife. 2023 May 25; 12.
-
Akirtava C, May GE, McManus CJ. False-positive IRESes from Hoxa9 and other genes resulting from errors in mammalian 5' UTR annotations. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2122170119.
-
Uppala JK, Sathe L, Chakraborty A, Bhattacharjee S, Pulvino AT, Dey M. The cap-proximal RNA secondary structure inhibits preinitiation complex formation on HAC1 mRNA. J Biol Chem. 2022 03; 298(3):101648.
-
Liu S, Koneru PC, Li W, Pathirage C, Engelman AN, Kvaratskhelia M, Musier-Forsyth K. HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio. Retrovirology. 2021 11 22; 18(1):37.
-
Li Y, Li J, Wang J, Lynch DR, Shen X, Corey DR, Parekh D, Bhat B, Woo C, Cherry JJ, Napierala JS, Napierala M. Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression. Nucleic Acids Res. 2021 11 18; 49(20):11560-11574.
-
Hood VL, Berger R, Freedman R, Law AJ. Transcription of PIK3CD in human brain and schizophrenia: regulation by proinflammatory cytokines. Hum Mol Genet. 2019 10 01; 28(19):3188-3198.
-
Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D. Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nat Med. 2019 02; 25(2):301-311.
-
Hartwick EW, Costantino DA, MacFadden A, Nix JC, Tian S, Das R, Kieft JS. Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels. Nat Commun. 2018 11 29; 9(1):5074.
-
Wang B, Eckert C, Maness PC, Yu J. A Genetic Toolbox for Modulating the Expression of Heterologous Genes in the Cyanobacterium Synechocystis sp. PCC 6803. ACS Synth Biol. 2018 01 19; 7(1):276-286.
-
Hassan MA, Vasquez JJ, Guo-Liang C, Meissner M, Nicolai Siegel T. Comparative ribosome profiling uncovers a dominant role for translational control in Toxoplasma gondii. BMC Genomics. 2017 Dec 11; 18(1):961.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|