 NAV1.6 Voltage-Gated Sodium Channel
"NAV1.6 Voltage-Gated Sodium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated sodium channel subtype found widely expressed in neurons of the central and peripheral nervous systems. Defects in the SCN8A gene which codes for the alpha subunit of this sodium channel are associated with ATAXIA and cognitive deficits.
| Descriptor ID |
D062557
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| MeSH Number(s) |
D12.776.157.530.400.875.750.600 D12.776.543.550.450.875.750.600 D12.776.543.585.400.875.750.600 D12.776.631.960.600
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| Concept/Terms |
NAV1.6 Voltage-Gated Sodium Channel- NAV1.6 Voltage-Gated Sodium Channel
- NAV1.6 Voltage Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 8
- Voltage Gated Sodium Channel Type 8
- Type 8 Voltage-Gated Sodium Channel
- Type 8 Voltage Gated Sodium Channel
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Below are MeSH descriptors whose meaning is more general than "NAV1.6 Voltage-Gated Sodium Channel".
Below are MeSH descriptors whose meaning is more specific than "NAV1.6 Voltage-Gated Sodium Channel".
This graph shows the total number of publications written about "NAV1.6 Voltage-Gated Sodium Channel" by people in this website by year, and whether "NAV1.6 Voltage-Gated Sodium Channel" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 3 | 3 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "NAV1.6 Voltage-Gated Sodium Channel" by people in Profiles.
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Meredith FL, Rennie KJ. Persistent and resurgent Na+ currents in vestibular calyx afferents. J Neurophysiol. 2020 08 01; 124(2):510-524.
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Wright MA, Mo W, Nicolson T, Ribera AB. In vivo evidence for transdifferentiation of peripheral neurons. Development. 2010 Sep; 137(18):3047-56.
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Moreno RL, Ribera AB. Developmental regulation of subtype-specific motor neuron excitability. Ann N Y Acad Sci. 2010 Jun; 1198:201-7.
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Osorio N, Cathala L, Meisler MH, Crest M, Magistretti J, Delmas P. Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. J Physiol. 2010 Feb 15; 588(Pt 4):651-70.
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Yonkers MA, Ribera AB. Molecular components underlying nongenomic thyroid hormone signaling in embryonic zebrafish neurons. Neural Dev. 2009 Jun 08; 4:20.
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Pineda RH, Svoboda KR, Wright MA, Taylor AD, Novak AE, Gamse JT, Eisen JS, Ribera AB. Knockdown of Nav1.6a Na+ channels affects zebrafish motoneuron development. Development. 2006 Oct; 133(19):3827-36.
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Pan F, Beam KG. The absence of resurgent sodium current in mouse spinal neurons. Brain Res. 1999 Dec 04; 849(1-2):162-8.
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