Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Kelly G Knupp

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stillman C, Knupp K, Oliver J, Conley A, Kennedy K, Silveira L, Joshi C. A retrospective analysis of pediatric patients on a ketogenic diet: A comparison of inpatient versus outpatient diet initiations. Epilepsy Res. 2025 Apr 29; 214:107556. PMID: 40315550.
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    2. Golnari P, Prantzalos K, Hood V, Meskis MA, Isom LL, Wilcox K, Parent JM, Lal D, Lhatoo SD, Goodkin HP, Wirrell EC, Knupp KG, Patel M, Loeb JA, Sullivan JE, Harte-Hargrove L, Fureman BE, Buchhalter J, Sahoo SS. Ontology accelerates few-shot learning capability of large language model: A study in extraction of drug efficacy in a rare pediatric epilepsy. Int J Med Inform. 2025 Sep; 201:105942. PMID: 40311258.
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    3. Condon C, Parkerson KA, Dandurand A, Wang F, Howse C, Mayhew M, Whyman S, Ventola P, Anne Meskis M, Sullivan J, Knupp KG, Gater A, Mahon-Smith A. Qualitative evaluation of meaningful change in Dravet syndrome as measured by the Vineland-3: Caregiver and clinician perspectives. Epilepsy Behav. 2025 Jun; 167:110381. PMID: 40188607.
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    4. Figueroa AG, Fulton RE, Banerji R, Knupp KG, Patel MN. Mitochondrial respiration defects in lymphoblast cell lines from patients with Dravet syndrome. Epilepsia. 2025 Mar 22. PMID: 40119852.
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    5. Rong M, Marques PT, Ali QZ, Morcos R, Chandran I, Qaiser F, M?ller RS, Bayat A, Rubboli G, Gardella E, Reuter MS, Sands TT, Scheffer IE, Schneider A, Poduri A, Wirrell E, Nabbout R, Sullivan J, Valente K, Auvin S, Knupp KG, Brunklaus A, Aledo-Serrano ?, Andrade DM. Variants in ATP6V0C are associated with Dravet-like developmental and epileptic encephalopathy. Epilepsia. 2025 Mar 14. PMID: 40085430.
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    6. Chen H, Numis AL, Shellhaas RA, Mytinger JR, Samanta D, Singh RK, Hussain SA, Takacs D, Knupp KG, Shao LR, Stafstrom CE. Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21. Front Pediatr. 2025; 13:1498425. PMID: 40013114.
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    7. Pellinen J, Sillau S, Morrison C, Maruff P, O'Brien TJ, Penovich P, French J, Knupp KG, Barnard S, Holmes M, Hegde M, Kanner AM, Meador KJ. Cognitive function at the time of focal epilepsy diagnosis is not associated with treatment resistance. Epilepsy Behav. 2025 Mar; 164:110293. PMID: 39923719.
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    8. Eschbach K, Reedy J, Gofton T, Gopaul M, Farias-Moeller R, Kellogg M, Knupp K, Hirsch LJ, Wong N, Dorsey Holliman B. Navigating life after New-onset refractory status epilepticus (NORSE) and Febrile infection-related epilepsy syndrome (FIRES): Insights from caregiver and patient interviews. Epilepsy Behav. 2025 Feb; 163:110236. PMID: 39740258.
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    9. Wheless JW, Raskin JS, Fine AL, Knupp KG, Schreiber J, Ostendorf AP, Albert GW, Kossoff EH, Madsen JR, Kotagal P, Numis AL, Gadgil N, Holder DL, Thiele EA, Ibrahim GM. Expert opinion on use of vagus nerve stimulation therapy in the management of pediatric epilepsy: A Delphi consensus study. Seizure. 2024 Dec; 123:97-103. PMID: 39536380.
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    10. Starosta RT, Larson AA, Meeks NJL, Gracie S, Friederich MW, Gaughan SM, Baker PR, Knupp KG, Michel CR, Reisdorph R, Hock DH, Stroud DA, Wood T, Van Hove JLK. An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis. Mitochondrion. 2024 Nov; 79:101973. PMID: 39413893.
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    11. Pellinen J, Sillau S, Morrison C, Maruff P, O'Brien TJ, Penovich P, French J, Knupp KG, Meador KJ. Engagement in online cognitive testing with the Cogstate brief battery among a multinational cohort of people with focal epilepsy. Epilepsy Behav. 2024 Oct; 159:109953. PMID: 39121756.
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    12. Abbott MJ, Knupp KG. SCN8A modified Delphi commentary. Epilepsia. 2024 Aug; 65(8):2339-2340. PMID: 38943498.
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    13. Gil-Nagel A, Cross JH, Devinsky O, Ceulemans B, Lagae L, Knupp K, Schoonjans AS, Ryvlin P, Thiele EA, Polega S, Lothe A, Nabbout R. Comprehensive scoping review of fenfluramine's role in managing generalized tonic-clonic seizures in developmental and epileptic encephalopathies. Epilepsia. 2024 Aug; 65(8):2186-2199. PMID: 39030735.
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    14. Mason JA, Juarez-Colunga E, Knupp KG. Electrographic screening for infantile epileptic spasms syndrome in a single sleep-wake cycle. Epilepsia. 2024 Jun; 65(6):1737-1743. PMID: 38572956.
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    15. Snyder E, Sillau S, Knupp KG, French J, Khanna A, Birlea M, Nair K, Pellinen J. Testing the diagnostic accuracy of common questions for seizure diagnosis: Challenges and future directions. Epilepsy Behav. 2024 Apr; 153:109686. PMID: 38401417.
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    16. Sullivan J, Wirrell E, Knupp KG, Chen D, Flamini R, Zafar M, Ventola P, Avenda?o J, Wang F, Parkerson KA, Ticho B. Adaptive functioning and neurodevelopment in patients with Dravet syndrome: 12-month interim analysis of the BUTTERFLY observational study. Epilepsy Behav. 2024 Feb; 151:109604. PMID: 38219604.
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    17. Auvin S, Arzimanoglou A, Brambilla I, French J, Knupp KG, Lagae L, Perucca E, Trinka E, Dlugos D. Call for the use of the ILAE terminology for seizures and epilepsies by health care professionals and regulatory agencies to benefit patients and caregivers. Epilepsia. 2024 Feb; 65(2):283-286. PMID: 38105624.
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    18. Perry MS, Scheffer IE, Sullivan J, Brunklaus A, Boronat S, Wheless JW, Laux L, Patel AD, Roberts CM, Dlugos D, Holder D, Knupp KG, Lallas M, Phillips S, Segal E, Smeyers P, Lal D, Wirrell E, Zuberi S, Br?nger T, Wojnaroski M, Maru B, O'Donnell P, Morton M, James E, Vila MC, Huang N, Gofshteyn JS, Rico S. Severe communication delays are independent of seizure burden and persist despite contemporary treatments in SCN1A+ Dravet syndrome: Insights from the ENVISION natural history study. Epilepsia. 2024 Feb; 65(2):322-337. PMID: 38049202.
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    19. Sullivan J, Lagae L, Cross JH, Devinsky O, Guerrini R, Knupp KG, Laux L, Nikanorova M, Polster T, Talwar D, Ceulemans B, Nabbout R, Farfel GM, Galer BS, Gammaitoni AR, Lock M, Agarwal A, Scheffer IE. Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial. Epilepsia. 2023 Oct; 64(10):2653-2666. PMID: 37543865.
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    20. Smith KM, Wirrell EC, Andrade DM, Choi H, Trenit? DK, Jones H, Knupp KG, Mugar J, Nordli DR, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. Clinical presentation and evaluation of epilepsy with eyelid myoclonia: Results of an international expert consensus panel. Epilepsia. 2023 09; 64(9):2330-2341. PMID: 37329145.
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    21. Smith KM, Wirrell EC, Andrade DM, Choi H, Trenit? DK, Jones H, Knupp KG, Mugar J, Nordli DR, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. Management of epilepsy with eyelid myoclonia: Results of an international expert consensus panel. Epilepsia. 2023 09; 64(9):2342-2350. PMID: 37326215.
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    22. Nelson JA, Knupp KG. Lennox-Gastaut Syndrome: Current Treatments, Novel Therapeutics, and Future Directions. Neurotherapeutics. 2023 09; 20(5):1255-1262. PMID: 37353676.
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    23. Smith KM, Wirrell EC, Andrade DM, Choi H, Trenit? DK, Knupp KG, Nordli DR, Riva A, Stern JM, Striano P, Thiele EA, Zawar I. A comprehensive narrative review of epilepsy with eyelid myoclonia. Epilepsy Res. 2023 07; 193:107147. PMID: 37121024.
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    24. Bishop KI, Isquith PK, Gioia GA, Knupp KG, Scheffer IE, Nabbout R, Specchio N, Sullivan J, Auvin S, Helen Cross J, Guerrini R, Farfel G, Galer BS, Gammaitoni AR. Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment. Epilepsy Behav. 2023 01; 138:108994. PMID: 36463826.
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    25. Knupp KG, Scheffer IE, Ceulemans B, Sullivan J, Nickels KC, Lagae L, Guerrini R, Zuberi SM, Nabbout R, Riney K, Agarwal A, Lock M, Dai D, Farfel GM, Galer BS, Gammaitoni AR, Polega S, Davis R, Gil-Nagel A. Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study. Epilepsia. 2023 01; 64(1):139-151. PMID: 36196777.
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    26. Sullivan J, Wirrell E, Knupp KG, Chen D, Zafar M, Flamini R, Stutely J, Brathwaite C, Ventola P, Avenda?o J, Parkerson KA, Wyant N, Ticho B. Interim results of adaptive functioning and neurodevelopment in BUTTERFLY - An observational study of children and adolescents with Dravet syndrome. Epilepsy Behav. 2022 12; 137(Pt A):108955. PMID: 36332561.
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    27. Knupp KG, Scheffer IE, Ceulemans B, Sullivan JE, Nickels KC, Lagae L, Guerrini R, Zuberi SM, Nabbout R, Riney K, Shore S, Agarwal A, Lock M, Farfel GM, Galer BS, Gammaitoni AR, Davis R, Gil-Nagel A. Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome: A Randomized Clinical Trial. JAMA Neurol. 2022 06 01; 79(6):554-564. PMID: 35499850.
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    28. Wirrell EC, Hood V, Knupp KG, Meskis MA, Nabbout R, Scheffer IE, Wilmshurst J, Sullivan J. International consensus on diagnosis and management of Dravet syndrome. Epilepsia. 2022 07; 63(7):1761-1777. PMID: 35490361.
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    29. Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 07; 92(1):32-44. PMID: 35388521.
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    30. Sempio C, Almaraz-Quinones N, Jackson M, Zhao W, Wang GS, Liu Y, Leehey M, Knupp K, Klawitter J, Christians U, Klawitter J. Simultaneous Quantification of 17 Cannabinoids by LC-MS-MS in Human Plasma. J Anal Toxicol. 2022 Apr 21; 46(4):383-392. PMID: 33754154.
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    31. Hood V, Berg AT, Knupp KG, Koh S, Laux L, Meskis MA, Zulfiqar-Ali Q, Perry MS, Scheffer IE, Sullivan J, Wirrell E, Andrade DM. COVID-19 vaccine in patients with Dravet syndrome: Observations and real-world experiences. Epilepsia. 2022 07; 63(7):1778-1786. PMID: 35383912.
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    32. Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 03; 37(3):186-193. PMID: 35044272.
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    33. Pellinen J, Snyder E, Knupp KG. The language of seizure identification: A qualitative investigation. Epilepsy Behav. 2022 01; 126:108484. PMID: 34915429.
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    34. Pellinen J, French J, Knupp KG. Diagnostic Delay in Epilepsy: the Scope of the Problem. Curr Neurol Neurosci Rep. 2021 11 24; 21(12):71. PMID: 34817723.
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    35. Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell EC, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell WG, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Sep 20; 97(12):e1217-e1228. PMID: 34266919.
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    36. Andrade DM, Berg AT, Hood V, Knupp KG, Koh S, Laux L, Meskis MA, Miller I, Perry MS, Scheffer IE, Sullivan J, Villas N, Wirrell E. Dravet syndrome: A quick transition guide for the adult neurologist. Epilepsy Res. 2021 Nov; 177:106743. PMID: 34624600.
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    37. Isom LL, Knupp KG. Dravet Syndrome: Novel Approaches for the Most Common Genetic Epilepsy. Neurotherapeutics. 2021 07; 18(3):1524-1534. PMID: 34378168.
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    38. Gil-Nagel A, Sullivan J, Ceulemans B, Wirrell E, Devinsky O, Nabbout R, Knupp KG, Scott Perry M, Polster T, Davis R, Lock M, Cortes RM, Gammaiton AR, Farfel G, Galer BS, Agarwal A. Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth. Epilepsy Behav. 2021 09; 122:108212. PMID: 34352670.
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    39. Min JY, Knupp KG, Patel AD, Shellhaas RA, Zhang M, Grinspan ZM. Medication selection, health services outcomes, and cost trajectories for Medicaid beneficiaries with infantile spasms. Epilepsy Res. 2021 10; 176:106733. PMID: 34333373.
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    40. Nelson JA, Demarest S, Thomas J, Juarez-Colunga E, Knupp KG. Evolution of Infantile Spasms to Lennox-Gastaut Syndrome: What Is There to Know? J Child Neurol. 2021 08; 36(9):752-759. PMID: 33764203.
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    41. Van Nuland A, Ivanenko A, Meskis MA, Villas N, Knupp KG, Berg AT. Sleep in Dravet syndrome: A parent-driven survey. Seizure. 2021 Feb; 85:102-110. PMID: 33453590.
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    42. Berg AT, Gaebler-Spira D, Wilkening G, Zelko F, Knupp K, Dixon-Salazar T, Villas N, Meskis MA, Harwell V, Thompson T, Sims S, Nesbitt G. Nonseizure consequences of Dravet syndrome, KCNQ2-DEE, KCNB1-DEE, Lennox-Gastaut syndrome, ESES: A functional framework. Epilepsy Behav. 2020 10; 111:107287. PMID: 32759067.
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    43. Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Leonard J, Heard K, Bajaj L. Disposition of Oral Cannabidiol-Rich Cannabis Extracts in Children with Epilepsy. Clin Pharmacokinet. 2020 08; 59(8):1005-1012. PMID: 32048179.
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    44. Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 11; 35(13):924-933. PMID: 32666891.
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    45. Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 10; 35(12):828-834. PMID: 32576057.
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    46. Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Pomeroy SL, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Crisis Standard of Care: Management of Infantile Spasms during COVID-19. Ann Neurol. 2020 08; 88(2):215-217. PMID: 32445204.
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    47. Messer R, Knupp KG. Infantile Spasms: Opportunities to Improve Care. Semin Neurol. 2020 04; 40(2):236-245. PMID: 32143232.
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    48. Nabbout R, Mistry A, Zuberi S, Villeneuve N, Gil-Nagel A, Sanchez-Carpintero R, Stephani U, Laux L, Wirrell E, Knupp K, Chiron C, Farfel G, Galer BS, Morrison G, Lock M, Agarwal A, Auvin S. Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial. JAMA Neurol. 2020 03 01; 77(3):300-308. PMID: 31790543.
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    49. Lagae L, Sullivan J, Knupp K, Laux L, Polster T, Nikanorova M, Devinsky O, Cross JH, Guerrini R, Talwar D, Miller I, Farfel G, Galer BS, Gammaitoni A, Mistry A, Morrison G, Lock M, Agarwal A, Lai WW, Ceulemans B. Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2019 12 21; 394(10216):2243-2254. PMID: 31862249.
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    50. McGarry L, Messer R, Cree-Green M, Ray K, Knupp K. Incidence of Hypertension Among Children Treated With Adrenocorticotropic Hormone (ACTH) or Prednisolone for Infantile Spasms. J Child Neurol. 2020 03; 35(3):215-220. PMID: 31769329.
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    51. Sorin LM, Knupp KG, Berg AT. New-onset seizure survey of epilepsy centers in the United States. Epilepsy Behav. 2019 12; 101(Pt A):106579. PMID: 31677582.
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    52. Knupp KG, Rice JD, Helmkamp LJ, Galinkin J, Sempio C, Jost K, Chapman KE. Prospective evaluation of oral cannabis extracts in children with epilepsy. Seizure. 2019 Nov; 72:23-27. PMID: 31550641.
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    53. Auvin S, French J, Dlugos D, Knupp KG, Perucca E, Arzimanoglou A, Whalen E, Shellhaas RA. Novel study design to assess the efficacy and tolerability of antiseizure medications for focal-onset seizures in infants and young children: A consensus document from the regulatory task force and the pediatric commission of the International League against Epilepsy (ILAE), in collaboration with the Pediatric Epilepsy Research Consortium (PERC). Epilepsia Open. 2019 Dec; 4(4):537-543. PMID: 31819909.
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    54. Berg AT, Wusthoff C, Shellhaas RA, Loddenkemper T, Grinspan ZM, Saneto RP, Knupp KG, Patel A, Sullivan JE, Kossoff EH, Chu CJ, Massey S, Valencia I, Keator C, Wirrell EC, Coryell J, Millichap JJ, Gaillard WD. Immediate outcomes in early life epilepsy: A contemporary account. Epilepsy Behav. 2019 08; 97:44-50. PMID: 31181428.
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    55. Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Heard K, Bajaj L. Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. Clin Toxicol (Phila). 2020 02; 58(2):124-128. PMID: 31111749.
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    56. Eschbach K, Knupp KG. Stiripentol for the treatment of seizures in Dravet syndrome. Expert Rev Clin Pharmacol. 2019 May; 12(5):379-388. PMID: 31017478.
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    57. Daniels D, Knupp K, Benke T, Wolter-Warmerdam K, Moran M, Hickey F. Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response. Glob Pediatr Health. 2019; 6:2333794X18821939. PMID: 30671494.
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    58. Ziobro J, Eschbach K, Sullivan JE, Knupp KG. Current Treatment Strategies and Future Treatment Options for Dravet Syndrome. Curr Treat Options Neurol. 2018 Oct 13; 20(12):52. PMID: 30315507.
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    59. Tolete P, Knupp K, Karlovich M, DeCarlo E, Bluvstein J, Conway E, Friedman D, Dugan P, Devinsky O. Lorcaserin therapy for severe epilepsy of childhood onset: A case series. Neurology. 2018 10 30; 91(18):837-839. PMID: 30258026.
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    60. Coryell J, Gaillard WD, Shellhaas RA, Grinspan ZM, Wirrell EC, Knupp KG, Wusthoff CJ, Keator C, Sullivan JE, Loddenkemper T, Patel A, Chu CJ, Massey S, Novotny EJ, Saneto RP, Berg AT. Neuroimaging of Early Life Epilepsy. Pediatrics. 2018 09; 142(3). PMID: 30089657.
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    61. Knupp KG, Wirrell EC. Correction to: Treatment Strategies for Dravet Syndrome. CNS Drugs. 2018 08; 32(8):783. PMID: 30027402.
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    62. Kelley SA, Knupp KG. Infantile Spasms-Have We Made Progress? Curr Neurol Neurosci Rep. 2018 04 19; 18(5):27. PMID: 29671077.
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    63. Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 04 01; 172(4):352-360. PMID: 29435578.
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    64. Knupp KG, Wirrell EC. Treatment Strategies for Dravet Syndrome. CNS Drugs. 2018 04; 32(4):335-350. PMID: 29594870.
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    65. Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13(3):e0193599. PMID: 29518120.
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    66. Whittington MD, Knupp KG, Vanderveen G, Kim C, Gammaitoni A, Campbell JD. The direct and indirect costs of Dravet Syndrome. Epilepsy Behav. 2018 03; 80:109-113. PMID: 29414539.
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    67. Campbell JD, Whittington MD, Kim CH, VanderVeen GR, Knupp KG, Gammaitoni A. Assessing the impact of caring for a child with Dravet syndrome: Results of a caregiver survey. Epilepsy Behav. 2018 03; 80:152-156. PMID: 29414545.
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    68. Demarest ST, Shellhaas RA, Gaillard WD, Keator C, Nickels KC, Hussain SA, Loddenkemper T, Patel AD, Saneto RP, Wirrell E, S?nchez Fern?ndez I, Chu CJ, Grinspan Z, Wusthoff CJ, Joshi S, Mohamed IS, Stafstrom CE, Stack CV, Yozawitz E, Bluvstein JS, Singh RK, Knupp KG. The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium. Epilepsia. 2017 12; 58(12):2098-2103. PMID: 29105055.
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    69. Klawitter J, Sempio C, M?rlein S, De Bloois E, Klepacki J, Henthorn T, Leehey MA, Hoffenberg EJ, Knupp K, Wang GS, Hopfer C, Kinney G, Bowler R, Foreman N, Galinkin J, Christians U, Klawitter J. An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine. Ther Drug Monit. 2017 10; 39(5):556-564. PMID: 28640062.
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    70. Eschbach K, Scarbro S, Juarez-Colunga E, Allen V, Hsu S, Knupp K. Growth and endocrine function in children with Dravet syndrome. Seizure. 2017 Nov; 52:117-122. PMID: 29031192.
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    71. Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 09 01; 171(9):863-871. PMID: 28759667.
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    72. Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75:73-79. PMID: 28807611.
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    73. Wallace A, Allen V, Park K, Knupp K. Infantile Spasms and Injuries of Prematurity: Short-Term Treatment-Based Response and Long-Term Outcomes. J Child Neurol. 2017 Sep; 32(10):861-866. PMID: 28635418.
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    74. Knupp KG, Scarbro S, Wilkening G, Juarez-Colunga E, Kempe A, Dempsey A. Parental Perception of Comorbidities in Children With Dravet Syndrome. Pediatr Neurol. 2017 Nov; 76:60-65. PMID: 28982531.
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    75. Knupp KG. Hormonal therapy with vigabatrin is superior to hormonal therapy alone in infantile spasms. J Pediatr. 2017 05; 184:235-238. PMID: 28434569.
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    76. Jensen MP, Brunklaus A, Dorris L, Zuberi SM, Knupp KG, Galer BS, Gammaitoni AR. The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research. Epilepsy Behav. 2017 05; 70(Pt A):104-109. PMID: 28431364.
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    77. Bramswig NC, L?decke HJ, Hamdan FF, Altm?ller J, Beleggia F, Elcioglu NH, Freyer C, Gerkes EH, Demirkol YK, Knupp KG, Kuechler A, Li Y, Lowenstein DH, Michaud JL, Park K, Stegmann APA, Veenstra-Knol HE, Wieland T, Wollnik B, Engels H, Strom TM, Kleefstra T, Wieczorek D. Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability. Hum Genet. 2017 07; 136(7):821-834. PMID: 28393272.
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    78. Griffin A, Hamling KR, Knupp K, Hong S, Lee LP, Baraban SC. Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. Brain. 2017 03 01; 140(3):669-683. PMID: 28073790.
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    79. Wirrell EC, Laux L, Donner E, Jette N, Knupp K, Meskis MA, Miller I, Sullivan J, Welborn M, Berg AT. Optimizing the Diagnosis and Management of Dravet Syndrome: Recommendations From a North American Consensus Panel. Pediatr Neurol. 2017 03; 68:18-34.e3. PMID: 28284397.
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    80. Treat L, Chapman KE, Colborn KL, Knupp KG. Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients. Epilepsia. 2017 01; 58(1):123-127. PMID: 27859038.
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    81. Knupp KG, Leister E, Coryell J, Nickels KC, Ryan N, Juarez-Colunga E, Gaillard WD, Mytinger JR, Berg AT, Millichap J, Nordli DR, Joshi S, Shellhaas RA, Loddenkemper T, Dlugos D, Wirrell E, Sullivan J, Hartman AL, Kossoff EH, Grinspan ZM, Hamikawa L. Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort. Epilepsia. 2016 11; 57(11):1834-1842. PMID: 27615012.
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    82. Knupp KG, Coryell J, Nickels KC, Ryan N, Leister E, Loddenkemper T, Grinspan Z, Hartman AL, Kossoff EH, Gaillard WD, Mytinger JR, Joshi S, Shellhaas RA, Sullivan J, Dlugos D, Hamikawa L, Berg AT, Millichap J, Nordli DR, Wirrell E. Response to treatment in a prospective national infantile spasms cohort. Ann Neurol. 2016 Mar; 79(3):475-84. PMID: 26704170.
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    83. Kumar RM, Koh S, Knupp K, Handler MH, O'Neill BR. Surgery for infants with catastrophic epilepsy: an analysis of complications and efficacy. Childs Nerv Syst. 2015 Sep; 31(9):1479-91. PMID: 26022500.
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    84. Press CA, Knupp KG, Chapman KE. Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. Epilepsy Behav. 2015 Apr; 45:49-52. PMID: 25845492.
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    85. Knupp K, Wirrell E. Progressive myoclonic epilepsies: it takes a village to make a diagnosis. Neurology. 2014 Feb 04; 82(5):378-9. PMID: 24384640.
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    86. Knupp K, Koh S, Park K. Pediatric epilepsy: Five new things. Neurol Clin Pract. 2012 Mar; 2(1):40-47. PMID: 29443293.
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    87. Barberio M, Reiter PD, Kaufman J, Knupp K, Dobyns EL. Continuous infusion pentobarbital for refractory status epilepticus in children. J Child Neurol. 2012 Jun; 27(6):721-6. PMID: 22156786.
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    88. Reiter PD, Huff AD, Knupp KG, Valuck RJ. Intravenous levetiracetam in the management of acute seizures in children. Pediatr Neurol. 2010 Aug; 43(2):117-21. PMID: 20610122.
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    89. Rubin DH, Suecoff SA, Knupp KG. Headaches in children. Pediatr Ann. 2006 May; 35(5):345-53. PMID: 16722293.
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    90. Johns JM, Joyner PW, McMurray MS, Elliott DL, Hofler VE, Middleton CL, Knupp K, Greenhill KW, Lomas LM, Walker CH. The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. Pharmacol Biochem Behav. 2005 Aug; 81(4):769-85. PMID: 15996723.
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    91. Kulikova-Schupak R, Knupp KG, Pascual JM, Chin SS, Kairam R, Patterson MC. Rectal biopsy in the diagnosis of neuronal intranuclear hyaline inclusion disease. J Child Neurol. 2004 Jan; 19(1):59-62. PMID: 15032387.
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