 NAV1.2 Voltage-Gated Sodium Channel
"NAV1.2 Voltage-Gated Sodium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11.
| Descriptor ID |
D062551
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| MeSH Number(s) |
D12.776.157.530.400.875.750.200 D12.776.543.550.450.875.750.200 D12.776.543.585.400.875.750.200 D12.776.631.960.200
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| Concept/Terms |
NAV1.2 Voltage-Gated Sodium Channel- NAV1.2 Voltage-Gated Sodium Channel
- NAV1.2 Voltage Gated Sodium Channel
- Type 2 Voltage-Gated Sodium Channel
- Type 2 Voltage Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 2
- Voltage Gated Sodium Channel Type 2
Voltage-Gated Sodium Channel Type 2 Subunit alpha- Voltage-Gated Sodium Channel Type 2 Subunit alpha
- Voltage Gated Sodium Channel Type 2 Subunit alpha
- Voltage-Gated Sodium Channel Type 2 alpha Subunit
- Voltage Gated Sodium Channel Type 2 alpha Subunit
- Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit
- Sodium Channel Protein Type 2 Subunit alpha
- Sodium Channel, Voltage-Gated, Type II, alpha 1
- NAV1.2 alpha Subunit
- SCN2A Sodium Channel alpha Subunit
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Below are MeSH descriptors whose meaning is more general than "NAV1.2 Voltage-Gated Sodium Channel".
Below are MeSH descriptors whose meaning is more specific than "NAV1.2 Voltage-Gated Sodium Channel".
This graph shows the total number of publications written about "NAV1.2 Voltage-Gated Sodium Channel" by people in this website by year, and whether "NAV1.2 Voltage-Gated Sodium Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "NAV1.2 Voltage-Gated Sodium Channel" by people in Profiles.
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Schamiloglu S, Wu H, Zhou M, Kwan AC, Bender KJ. Dynamic Foraging Behavior Performance Is Not Affected by Scn2a Haploinsufficiency. eNeuro. 2023 Dec; 10(12).
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Berg AT, Palac H, Wilkening G, Zelko F, Schust Meyer L. SCN2A-Developmental and Epileptic Encephalopathies: Challenges to trial-readiness for non-seizure outcomes. Epilepsia. 2021 01; 62(1):258-268.
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Foster LA, Johnson MR, MacDonald JT, Karachunski PI, Henry TR, Nascene DR, Moran BP, Raymond GV. Infantile Epileptic Encephalopathy Associated With SCN2A Mutation Responsive to Oral Mexiletine. Pediatr Neurol. 2017 01; 66:108-111.
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