 Mucosal-Associated Invariant T Cells
"Mucosal-Associated Invariant T Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.
| Descriptor ID |
D000072336
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| MeSH Number(s) |
A11.118.637.555.567.550.500.100 A11.118.637.555.567.569.500.100 A15.145.229.637.555.567.550.500.100 A15.145.229.637.555.567.569.500.100 A15.382.490.555.567.550.500.100 A15.382.490.555.567.569.500.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosal-Associated Invariant T Cells".
Below are MeSH descriptors whose meaning is more specific than "Mucosal-Associated Invariant T Cells".
This graph shows the total number of publications written about "Mucosal-Associated Invariant T Cells" by people in this website by year, and whether "Mucosal-Associated Invariant T Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2016 | 2 | 0 | 2 | | 2018 | 2 | 1 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 3 | 1 | 4 | | 2022 | 3 | 0 | 3 |
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Below are the most recent publications written about "Mucosal-Associated Invariant T Cells" by people in Profiles.
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Gallagher C, Mahon JM, O'Neill C, Cassidy FC, Dunbar H, De Barra C, Cadden C, Pisarska MM, Wood NAW, Masterson JC, McNamee EN, Schrumpf E, English K, O'Shea D, Tobin AM, Hogan AE. Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu. J Invest Dermatol. 2023 06; 143(6):1094-1097.e2.
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Krovi SH, Loh L, Spengler A, Brunetti T, Gapin L. Current insights in mouse iNKT and MAIT cell development using single cell transcriptomics data. Semin Immunol. 2022 03; 60:101658.
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Suliman S, Kjer-Nielsen L, Iwany SK, Lopez Tamara K, Loh L, Grzelak L, Kedzierska K, Ocampo TA, Corbett AJ, McCluskey J, Rossjohn J, Le?n SR, Calderon R, Lecca-Garcia L, Murray MB, Moody DB, Van Rhijn I. Dual TCR-a Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation. J Immunol. 2022 03 15; 208(6):1389-1395.
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Harsha Krovi S, Zhang J, Michaels-Foster MJ, Brunetti T, Loh L, Scott-Browne J, Gapin L. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020 12 07; 11(1):6238.
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de Lima Moreira M, Souter MNT, Chen Z, Loh L, McCluskey J, Pellicci DG, Eckle SBG. Hypersensitivities following allergen antigen recognition by unconventional T cells. Allergy. 2020 10; 75(10):2477-2490.
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Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, Rossjohn J, Thomas PG, Eckle SBG, McCluskey J, Godfrey DI, Kedzierska K. Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRa? Clonotypes with Potent Antimicrobial Responses. J Immunol. 2020 03 01; 204(5):1119-1133.
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Hinks TSC, van Wilgenburg B, Wang H, Loh L, Koutsakos M, Kedzierska K, Corbett AJ, Chen Z. Study of MAIT Cell Activation in Viral Infections In Vivo. Methods Mol Biol. 2020; 2098:261-281.
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Souter MNT, Loh L, Li S, Meehan BS, Gherardin NA, Godfrey DI, Rossjohn J, Fairlie DP, Kedzierska K, Pellicci DG, Chen Z, Kjer-Nielsen L, Corbett AJ, McCluskey J, Eckle SBG. Characterization of Human Mucosal-associated Invariant T (MAIT) Cells. Curr Protoc Immunol. 2019 12; 127(1):e90.
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van Wilgenburg B, Loh L, Chen Z, Pediongco TJ, Wang H, Shi M, Zhao Z, Koutsakos M, N?ssing S, Sant S, Wang Z, D'Souza C, Jia X, Almeida CF, Kostenko L, Eckle SBG, Meehan BS, Kallies A, Godfrey DI, Reading PC, Corbett AJ, McCluskey J, Klenerman P, Kedzierska K, Hinks TSC. MAIT cells contribute to protection against lethal influenza infection in vivo. Nat Commun. 2018 11 09; 9(1):4706.
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Harms RZ, Lorenzo-Arteaga KM, Ostlund KR, Smith VB, Smith LM, Gottlieb P, Sarvetnick N. Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes. Front Immunol. 2018; 9:2332.
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