 alpha-Defensins
"alpha-Defensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.
| Descriptor ID |
D023084
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| MeSH Number(s) |
D12.644.050.200.050 D12.776.543.695.054.200.050
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "alpha-Defensins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Defensins".
This graph shows the total number of publications written about "alpha-Defensins" by people in this website by year, and whether "alpha-Defensins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Defensins" by people in Profiles.
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Shukla PK, Rao RG, Meena AS, Giorgianni F, Lee SC, Raju P, Shashikanth N, Shekhar C, Beranova S, Balazs L, Tigyi G, Gosain A, Rao R. Paneth cell dysfunction in radiation injury and radio-mitigation by human a-defensin 5. Front Immunol. 2023; 14:1174140.
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McMahan RH, Hulsebus HJ, Najarro KM, Giesy LE, Frank DN, Kovacs EJ. Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice. Alcohol. 2023 03; 107:136-143.
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Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
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Jones JC, Brindley CD, Elder NH, Myers MG, Rajala MW, Dekaney CM, McNamee EN, Frey MR, Shroyer NF, Dempsey PJ. Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019; 7(3):533-554.
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Kudryashova E, Koneru PC, Kvaratskhelia M, Str?mstedt AA, Lu W, Kudryashov DS. Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins. Sci Rep. 2016 09 01; 6:32499.
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Deirmengian C, Kardos K, Kilmartin P, Gulati S, Citrano P, Booth RE. The Alpha-defensin Test for Periprosthetic Joint Infection Responds to a Wide Spectrum of Organisms. Clin Orthop Relat Res. 2015 Jul; 473(7):2229-35.
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Deirmengian C, Kardos K, Kilmartin P, Cameron A, Schiller K, Booth RE, Parvizi J. The alpha-defensin test for periprosthetic joint infection outperforms the leukocyte esterase test strip. Clin Orthop Relat Res. 2015 Jan; 473(1):198-203.
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Zurek OW, Nygaard TK, Watkins RL, Pallister KB, Torres VJ, Horswill AR, Voyich JM. The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus. J Innate Immun. 2014; 6(1):21-30.
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Voglis S, Quinn K, Tullis E, Liu M, Henriques M, Zubrinich C, Pe?uelas O, Chan H, Silverman F, Cherepanov V, Orzech N, Khine AA, Cantin A, Slutsky AS, Downey GP, Zhang H. Human neutrophil peptides and phagocytic deficiency in bronchiectatic lungs. Am J Respir Crit Care Med. 2009 Jul 15; 180(2):159-66.
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Folkvord JM, McCarter MD, Ryder J, Meditz AL, Forster JE, Connick E. alpha-Defensins 1, 2, and 3 are expressed by granulocytes in lymphoid tissues of HIV-1-seropositive and -seronegative individuals. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):529-36.
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