 Activated Protein C Resistance
"Activated Protein C Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
| Descriptor ID |
D020016
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| MeSH Number(s) |
C15.378.100.100.037 C15.378.100.141.036 C15.378.925.050 C16.320.099.037
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Activated Protein C Resistance".
Below are MeSH descriptors whose meaning is more specific than "Activated Protein C Resistance".
This graph shows the total number of publications written about "Activated Protein C Resistance" by people in this website by year, and whether "Activated Protein C Resistance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Activated Protein C Resistance" by people in Profiles.
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Gupta A, Williams MD, Macias WL, Molitoris BA, Grinnell BW. Activated protein C and acute kidney injury: Selective targeting of PAR-1. Curr Drug Targets. 2009 Dec; 10(12):1212-26.
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Graf LL, Welsh CH, Qamar Z, Marlar RA. Activated protein C resistance assay detects thrombotic risk factors other than factor V Leiden. Am J Clin Pathol. 2003 Jan; 119(1):52-60.
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Selzman CH, Whitehill TA, Krupski WC. Thrombophilia and activated protein C resistance. Ann Vasc Surg. 1998 Nov; 12(6):601-4.
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