 Receptors, Interleukin-6
"Receptors, Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitogen-activated B-LYMPHOCYTES, and peripheral MONOCYTES. The receptors are heterodimers of the INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130.
| Descriptor ID |
D019947
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| MeSH Number(s) |
D12.776.543.750.705.852.420.400
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| Concept/Terms |
Receptors, Interleukin-6- Receptors, Interleukin-6
- Receptors, Interleukin 6
- IL-6 Receptors
- IL 6 Receptors
- Receptors, IL-6
- Receptors, IL 6
- IL6 Receptors
- Receptors, IL6
- Interleukin 6 Receptor
- Receptor, Interleukin 6
- Interleukin-6 Receptors
- Interleukin 6 Receptors
- IL-6 Receptor
- IL 6 Receptor
- Receptor, IL-6
- IL6 Receptor
- Receptor, IL6
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Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-6".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-6".
This graph shows the total number of publications written about "Receptors, Interleukin-6" by people in this website by year, and whether "Receptors, Interleukin-6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 1 | 2 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-6" by people in Profiles.
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Mac Giollabhui N, Foster S, Lowry CA, Mischoulon D, Raison CL, Nyer M. Interleukin-6 receptor antagonists in immunopsychiatry: Can they lead to increased interleukin-6 in the central nervous system (CNS) and worsening psychiatric symptoms? Brain Behav Immun. 2022 07; 103:202-204.
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Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Willi SM, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S. IL-6 receptor blockade does not slow ? cell loss in new-onset type 1 diabetes. JCI Insight. 2021 11 08; 6(21).
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Droho S, Cuda CM, Perlman H, Lavine JA. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021 09 10; 11(1):18084.
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Poppelaars F, Gaya da Costa M, Eskandari SK, Damman J, Seelen MA. Donor genetic variants in interleukin-6 and interleukin-6 receptor associate with biopsy-proven rejection following kidney transplantation. Sci Rep. 2021 08 13; 11(1):16483.
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Rosas IO, Br?u N, Waters M, Go RC, Hunter BD, Bhagani S, Skiest D, Aziz MS, Cooper N, Douglas IS, Savic S, Youngstein T, Del Sorbo L, Cubillo Gracian A, De La Zerda DJ, Ustianowski A, Bao M, Dimonaco S, Graham E, Matharu B, Spotswood H, Tsai L, Malhotra A. Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia. N Engl J Med. 2021 04 22; 384(16):1503-1516.
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Gupta S, Wang W, Hayek SS, Chan L, Mathews KS, Melamed ML, Brenner SK, Leonberg-Yoo A, Schenck EJ, Radbel J, Reiser J, Bansal A, Srivastava A, Zhou Y, Finkel D, Green A, Mallappallil M, Faugno AJ, Zhang J, Velez JCQ, Shaefi S, Parikh CR, Charytan DM, Athavale AM, Friedman AN, Redfern RE, Short SAP, Correa S, Pokharel KK, Admon AJ, Donnelly JP, Gershengorn HB, Douin DJ, Semler MW, Hern?n MA, Leaf DE. Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19. JAMA Intern Med. 2021 01 01; 181(1):41-51.
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Fujihara K, Bennett JL, de Seze J, Haramura M, Kleiter I, Weinshenker BG, Kang D, Mughal T, Yamamura T. Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology. Neurol Neuroimmunol Neuroinflamm. 2020 09 03; 7(5).
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Morrison AR, Johnson JM, Griebe KM, Jones MC, Stine JJ, Hencken LN, To L, Bianchini ML, Vahia AT, Swiderek J, Ramesh MS, Peters MA, Smith ZR. Clinical characteristics and predictors of survival in adults with coronavirus disease 2019 receiving tocilizumab. J Autoimmun. 2020 11; 114:102512.
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Scherger S, Henao-Mart?nez A, Franco-Paredes C, Shapiro L. Rethinking interleukin-6 blockade for treatment of COVID-19. Med Hypotheses. 2020 Nov; 144:110053.
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Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB. IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 07; 61(1):123-126.
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