 gamma Catenin
"gamma Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS and helps link their cytoplasmic tails to ACTIN in the CYTOSKELETON via ALPHA CATENIN. It is also found in DESMOSOMES where it mediates the link between DESMOSOMAL CADHERINS and DESMOPLAKIN.
| Descriptor ID |
D051185
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| MeSH Number(s) |
D12.776.091.500 D12.776.220.145.750
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| Concept/Terms |
gamma Catenin- gamma Catenin
- Catenin, gamma
- Desmoplakin III
- Junctional Plakoglobin
- Plakoglobin, Junctional
- Plakoglobin
- Junction Plakoglobin
- Plakoglobin, Junction
- gamma-Catenin
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Below are MeSH descriptors whose meaning is more general than "gamma Catenin".
Below are MeSH descriptors whose meaning is more specific than "gamma Catenin".
This graph shows the total number of publications written about "gamma Catenin" by people in this website by year, and whether "gamma Catenin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1997 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "gamma Catenin" by people in Profiles.
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Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018 09 01; 78(17):4971-4983.
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Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards MG, Kumar Karuppusamy Rathinam M, Zhao X, Wu PY, Tang K, Bikkavilli RK, Winn RA. Novel Role for ?-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1). J Biol Chem. 2015 Jun 19; 290(25):15610-15620.
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Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ. Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec; 133(12):2732-2740.
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Winn RA, Heasley LE. Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth. Chest. 2004 May; 125(5 Suppl):122S-3S.
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Cheng X, Koch PJ. In vivo function of desmosomes. J Dermatol. 2004 Mar; 31(3):171-87.
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Cheng X, Mihindukulasuriya K, Den Z, Kowalczyk AP, Calkins CC, Ishiko A, Shimizu A, Koch PJ. Assessment of splice variant-specific functions of desmocollin 1 in the skin. Mol Cell Biol. 2004 Jan; 24(1):154-63.
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Williams BO, Barish GD, Klymkowsky MW, Varmus HE. A comparative evaluation of beta-catenin and plakoglobin signaling activity. Oncogene. 2000 Nov 23; 19(50):5720-8.
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Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE. Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling. Mol Biol Cell. 1999 Oct; 10(10):3151-69.
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Merriam JM, Rubenstein AB, Klymkowsky MW. Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus. Dev Biol. 1997 May 01; 185(1):67-81.
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Kofron M, Spagnuolo A, Klymkowsky M, Wylie C, Heasman J. The roles of maternal alpha-catenin and plakoglobin in the early Xenopus embryo. Development. 1997 Apr; 124(8):1553-60.
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