 Lamin Type A
"Lamin Type A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.
| Descriptor ID |
D034904
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| MeSH Number(s) |
D12.776.660.650.875.500
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| Concept/Terms |
Lamin Type A- Lamin Type A
- Lamin A
- Type A Lamins
- Lamins, Type A
- Lamin A-C
- Lamin A C
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Below are MeSH descriptors whose meaning is more general than "Lamin Type A".
Below are MeSH descriptors whose meaning is more specific than "Lamin Type A".
This graph shows the total number of publications written about "Lamin Type A" by people in this website by year, and whether "Lamin Type A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 1 | 3 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 4 | 0 | 4 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lamin Type A" by people in Profiles.
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MacRae CA, Taylor MR, Mestroni L, Moses J, Ashley EA, Wheeler MT, Lakdawala NK, Hershberger RE, Sandor V, Saunders ME, Oliver C, Lee PA, Judge DP. Plain Language Summary of Publication of the safety and efficacy of ARRY-371797 in people with dilated cardiomyopathy and a faulty LMNA gene. Future Cardiol. 2023 02; 19(2):55-63.
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MacRae CA, Taylor MRG, Mestroni L, Moses J, Ashley EA, Wheeler MT, Lakdawala NK, Hershberger RE, Sandor V, Saunders ME, Oliver C, Lee PA, Judge DP. Efficacy and Safety of ARRY-371797 in LMNA-Related Dilated Cardiomyopathy: A Phase 2 Study. Circ Genom Precis Med. 2023 02; 16(1):e003730.
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Pe?a B, Gao S, Borin D, Del Favero G, Abdel-Hafiz M, Farahzad N, Lorenzon P, Sinagra G, Taylor MRG, Mestroni L, Sbaizero O. Cellular Biomechanic Impairment in Cardiomyocytes Carrying the Progeria Mutation: An Atomic Force Microscopy Investigation. Langmuir. 2022 12 06; 38(48):14928-14940.
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Judge DP, Lakdawala NK, Taylor MRG, Mestroni L, Li H, Oliver C, Angeli FS, Lee PA, MacRae CA. Long-Term Efficacy and Safety of ARRY-371797 (PF-07265803) in Patients With Lamin A/C-Related Dilated Cardiomyopathy. Am J Cardiol. 2022 11 15; 183:93-98.
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Sidhu K, Castrini AI, Parikh V, Reza N, Owens A, Tremblay-Gravel M, Wheeler MT, Mestroni L, Taylor M, Graw S, Gigli M, Merlo M, Paldino A, Sinagra G, Judge DP, Ramos H, Mesubi O, Brown E, Turnbull S, Kumar S, Roy D, Tedrow UB, Ngo L, Haugaa K, Lakdawala NK. The response to cardiac resynchronization therapy in LMNA cardiomyopathy. Eur J Heart Fail. 2022 04; 24(4):685-693.
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Sears RM, Roux KJ. Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in LMNA- and BANF1-Associated Progerias. Cells. 2022 03 02; 11(5).
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Gao S, Mumme-Monheit A, Chen SN, Spector EB, Slavov D, Baralle FE, Bristow MR, Mestroni L, Taylor MRG. An LMNA synonymous variant associated with severe dilated cardiomyopathy: Case report. Am J Med Genet A. 2022 02; 188(2):600-605.
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Lachaize V, Pe?a B, Ciubotaru C, Cojoc D, Chen SN, Taylor MRG, Mestroni L, Sbaizero O. Compromised Biomechanical Properties, Cell-Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation. Int J Mol Sci. 2021 Aug 25; 22(17).
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Malik F, Santiago T, Newman S, McCarville B, Pappo AS, Clay MR. An addition to the evolving spectrum of lipofibromatosis and lipofibromatosis-like neural tumor: Molecular findings in an unusual phenotype aid in accurate classification. Pathol Res Pract. 2020 Jun; 216(6):152942.
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Borin D, Pe?a B, Taylor MRG, Mestroni L, Lapasin R, Sbaizero O. Viscoelastic behavior of cardiomyocytes carrying LMNA mutations. Biorheology. 2020; 57(1):1-14.
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