Formate-Tetrahydrofolate Ligase
"Formate-Tetrahydrofolate Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carbon-nitrogen ligase that catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate in the presence of ATP. In higher eukaryotes the enzyme also contains METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP+) and METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE activity.
| Descriptor ID |
D005574
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| MeSH Number(s) |
D08.811.464.259.550
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| Concept/Terms |
Formate-Tetrahydrofolate Ligase- Formate-Tetrahydrofolate Ligase
- Formate Tetrahydrofolate Ligase
- Ligase, Formate-Tetrahydrofolate
- Formyltetrahydrofolate Synthetase
- Synthetase, Formyltetrahydrofolate
- Tetrahydrofolate Formylase
- Formylase, Tetrahydrofolate
|
Below are MeSH descriptors whose meaning is more general than "Formate-Tetrahydrofolate Ligase".
Below are MeSH descriptors whose meaning is more specific than "Formate-Tetrahydrofolate Ligase".
This graph shows the total number of publications written about "Formate-Tetrahydrofolate Ligase" by people in this website by year, and whether "Formate-Tetrahydrofolate Ligase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Formate-Tetrahydrofolate Ligase" by people in Profiles.
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Beaudin AE, Perry CA, Stabler SP, Allen RH, Stover PJ. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Am J Clin Nutr. 2012 Apr; 95(4):882-91.
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MacFarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem. 2009 Jan 16; 284(3):1533-9.