 Nuclear Receptor Co-Repressor 1
"Nuclear Receptor Co-Repressor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear protein that regulates the expression of genes involved in a diverse array of processes related to metabolism and reproduction. The protein contains three nuclear receptor interaction domains and three repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 2.
| Descriptor ID |
D056971
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| MeSH Number(s) |
D12.776.930.780.625.374
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| Concept/Terms |
Nuclear Receptor Co-Repressor 1- Nuclear Receptor Co-Repressor 1
- Nuclear Receptor Co Repressor 1
- RIP140 Repressor
- Nuclear Factor RIP140
- Receptor Interacting Protein 140
- Retinoid X Receptor-Interacting Protein 13
- Retinoid X Receptor Interacting Protein 13
- Nuclear Receptor Co-Repressor RIP140
- Nuclear Receptor Co Repressor RIP140
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Co-Repressor 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Co-Repressor 1".
This graph shows the total number of publications written about "Nuclear Receptor Co-Repressor 1" by people in this website by year, and whether "Nuclear Receptor Co-Repressor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Co-Repressor 1" by people in Profiles.
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Balasubramaniyan N, Devereaux MW, Orlicky DJ, Sokol RJ, Suchy FJ. miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis. J Biol Chem. 2021 12; 297(6):101400.
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Guo L, Chen C, Liang Q, Karim MZ, Gorska MM, Alam R. Nuclear translocation of MEK1 triggers a complex T cell response through the corepressor silencing mediator of retinoid and thyroid hormone receptor. J Immunol. 2013 Jan 01; 190(1):159-67.
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Finlin BS, Bodles-Brakhop AM, Yao-Borengasser A, Zhu B, Starnes CP, McGehee RE, Peterson CA, Kern PA, Rasouli N. Regulation of small ubiquitin-like modifier-1, nuclear receptor coreceptor, histone deacetylase 3, and peroxisome proliferator-activated receptor-? in human adipose tissue. Metab Syndr Relat Disord. 2012 Aug; 10(4):312-7.
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Astapova I, Vella KR, Ramadoss P, Holtz KA, Rodwin BA, Liao XH, Weiss RE, Rosenberg MA, Rosenzweig A, Hollenberg AN. The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. Mol Endocrinol. 2011 Feb; 25(2):212-24.
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Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer. Steroids. 2000 Oct-Nov; 65(10-11):579-84.
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Nagaya T, Chen KS, Fujieda M, Ohmori S, Richer JK, Horwitz KB, Lupski JR, Seo H. Localization of the human nuclear receptor corepressor (hN-CoR) gene between the CMT1A and the SMS critical regions of chromosome 17p11.2. Genomics. 1999 Aug 01; 59(3):339-41.
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Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, Horwitz KB. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Mol Endocrinol. 1997 Jun; 11(6):693-705.
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