Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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James M Flynn

TitleAffiliate
InstitutionUniversity of Colorado Boulder
DepartmentBehavioral Sci Inst-Admin

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gupta T, DeVries JT, Huang HC, Ross CS, Butzel D, Flynn JM, Young MN, Lahoud RN, Ittleman F, Hassan A, Dauerman HL. Trends in Isolated and Combined Aortic Valve Replacement for Severe Aortic Stenosis in Patients Younger Than 65 Years. Struct Heart. 2025 Aug; 9(8):100684. PMID: 40894373.
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    2. Yeatman S, Flynn JM, Stevenson A, Genadek K, Mollborn S, Menken J. Expanded Contraceptive Access Linked To Increase In College Completion Among Women In Colorado. Health Aff (Millwood). 2022 12; 41(12):1754-1762. PMID: 36469823.
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    3. Robich MP, Iribarne A, Butzel D, DiScipio AW, Dauerman HL, Leavitt BJ, DeSimone JP, Coylewright M, Flynn JM, Westbrook BM, Ver Lee PN, Zaky M, Quinn R, Malenka DJ. Multicenter experience with valve-in-valve transcatheter aortic valve replacement compared with primary, native valve transcatheter aortic valve replacement. J Card Surg. 2022 Dec; 37(12):4382-4388. PMID: 36448467.
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    4. Sharma T, Tapales AJD, Ross CS, Malenka DJ, Flynn JM, Ferguson M, Young MN, Vasaiwala S, Kramer RS, Iribarne A, Dauerman HL. Concordance of Guideline-Based Risk Stratification and Selection of Patients for Transcatheter Aortic Valve Implantation or Surgical Replacement. Am J Cardiol. 2022 06 15; 173:94-99. PMID: 35367045.
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    5. Denkmann JH, Malenka DJ, Ramkumar N, Ross CS, Young MN, Vasaiwal S, Flynn JM, Dauerman HL. Decade Long Temporal Trends in Revascularization for Patients With Diabetes Mellitus (From the Northern New England Cardiovascular Disease Study Group). Am J Cardiol. 2021 10 15; 157:1-7. PMID: 34399969.
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    6. Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston APW, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA. Retraction Note to: Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2021 Mar 30; 11(1):8. PMID: 33785048.
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    7. Lahoud R, Butzel DW, Parsee A, Huang YL, Solomon RJ, DeVries JT, Flynn JM, Iribarne A, Lee PV, Ross CS, Malenka DJ, Dauerman HL. Acute Kidney Recovery in Patients Who Underwent Transcatheter Versus Surgical Aortic Valve Replacement (from the Northern New England Cardiovascular Disease Study Group). Am J Cardiol. 2020 03 01; 125(5):788-794. PMID: 31924319.
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    8. Azarbal A, Malenka DJ, Huang YL, Ross CS, Solomon RJ, DeVries JT, Flynn JM, Butzel D, McKay M, Dauerman HL. Recovery of Kidney Dysfunction After Transcatheter Aortic Valve Implantation (from the Northern New England Cardiovascular Disease Study Group). Am J Cardiol. 2019 02 01; 123(3):426-433. PMID: 30522749.
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    9. Wiley CD, Flynn JM, Morrissey C, Lebofsky R, Shuga J, Dong X, Unger MA, Vijg J, Melov S, Campisi J. Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence. Aging Cell. 2017 10; 16(5):1043-1050. PMID: 28699239.
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    10. Tomiyama AJ, Milush JM, Lin J, Flynn JM, Kapahi P, Verdin E, Sinclair E, Melov S, Epel ES. Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. Nutr Healthy Aging. 2017 Mar 31; 4(2):147-156. PMID: 28447069.
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    11. Myagmar BE, Flynn JM, Cowley PM, Swigart PM, Montgomery MD, Thai K, Nair D, Gupta R, Deng DX, Hosoda C, Melov S, Baker AJ, Simpson PC. Adrenergic Receptors in Individual Ventricular Myocytes: The Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent. Circ Res. 2017 Mar 31; 120(7):1103-1115. PMID: 28219977.
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    12. Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston AP, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016; 6:7. PMID: 26834962.
      View in: PubMed
    13. Neragi-Miandoab S, Westbrook B, Flynn J, Blakely J, Baribeau Y. Prosthetic valve endocarditis five months following transcatheter aortic valve implantation and review of literature. Heart Surg Forum. 2015 Feb 27; 18(1):E20-2. PMID: 25881218.
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    14. Uthamalingam S, Ahmado I, Selvaraj V, Dewey R, Flynn J. Long term outcomes in octogenarians undergoing percutaneous coronary intervention: comparison of bare metal versus drug eluting stent. Int J Cardiol. 2015 Jan 20; 179:385-9. PMID: 25464492.
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    15. Zykovich A, Hubbard A, Flynn JM, Tarnopolsky M, Fraga MF, Kerksick C, Ogborn D, MacNeil L, Mooney SD, Melov S. Genome-wide DNA methylation changes with age in disease-free human skeletal muscle. Aging Cell. 2014 Apr; 13(2):360-6. PMID: 24304487.
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    16. Flynn JM, O'Leary MN, Zambataro CA, Academia EC, Presley MP, Garrett BJ, Zykovich A, Mooney SD, Strong R, Rosen CJ, Kapahi P, Nelson MD, Kennedy BK, Melov S. Late-life rapamycin treatment reverses age-related heart dysfunction. Aging Cell. 2013 Oct; 12(5):851-62. PMID: 23734717.
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    17. Flynn JM, Melov S. SOD2 in mitochondrial dysfunction and neurodegeneration. Free Radic Biol Med. 2013 Sep; 62:4-12. PMID: 23727323.
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    18. Flynn JM, Spusta SC, Rosen CJ, Melov S. Single cell gene expression profiling of cortical osteoblast lineage cells. Bone. 2013 Mar; 53(1):174-81. PMID: 23238121.
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    19. Choi SW, Gerencser AA, Ng R, Flynn JM, Melov S, Danielson SR, Gibson BW, Nicholls DG, Bredesen DE, Brand MD. No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease. J Neurosci. 2012 Nov 21; 32(47):16775-84. PMID: 23175831.
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    20. Flynn JM, Czerwieniec GA, Choi SW, Day NU, Gibson BW, Hubbard A, Melov S. Proteogenomics of synaptosomal mitochondrial oxidative stress. Free Radic Biol Med. 2012 Sep 01; 53(5):1048-60. PMID: 22796328.
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    21. Uthamalingam S, Gurm GS, Ahmado I, Sidhu MS, Flynn J. Outcome of patients with regadenoson-induced ST-segment depression but normal perfusion on single-photon emission computed tomography. Angiology. 2013 Jan; 64(1):46-8. PMID: 22323835.
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    22. Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY). 2012 Jan; 4(1):3-12. PMID: 22278880.
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    23. Flynn JM, Santana LF, Melov S. Single cell transcriptional profiling of adult mouse cardiomyocytes. J Vis Exp. 2011 Dec 28; (58):e3302. PMID: 22231655.
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    24. Uthamalingam S, Gurm GS, Daley M, Flynn J, Capodilupo R. Usefulness of acute delirium as a predictor of adverse outcomes in patients >65 years of age with acute decompensated heart failure. Am J Cardiol. 2011 Aug 01; 108(3):402-8. PMID: 21757045.
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    25. Flynn JM, Choi SW, Day NU, Gerencser AA, Hubbard A, Melov S. Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice. Free Radic Biol Med. 2011 Apr 01; 50(7):866-73. PMID: 21215798.
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    26. Flynn JM, Lannigan DA, Clark DE, Garner MH, Cammarata PR. RNA suppression of ERK2 leads to collapse of mitochondrial membrane potential with acute oxidative stress in human lens epithelial cells. Am J Physiol Endocrinol Metab. 2008 Mar; 294(3):E589-99. PMID: 18171912.
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    27. Flynn JM, Cammarata PR. Estradiol attenuates mitochondrial depolarization in polyol-stressed lens epithelial cells. Mol Vis. 2006 Apr 04; 12:271-82. PMID: 16617294.
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    28. Cammarata PR, Flynn J, Gottipati S, Chu S, Dimitrijevich S, Younes M, Skliris G, Murphy LC. Differential expression and comparative subcellular localization of estrogen receptor beta isoforms in virally transformed and normal cultured human lens epithelial cells. Exp Eye Res. 2005 Aug; 81(2):165-75. PMID: 16080910.
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    29. Moor AN, Flynn JM, Gottipati S, Giblin FJ, Cammarata PR. 17beta-estradiol stimulates MAPK signaling pathway in human lens epithelial cell cultures preventing collapse of mitochondrial membrane potential during acute oxidative stress. Mitochondrion. 2005 Aug; 5(4):235-47. PMID: 16050986.
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    30. Walker EA, Mertz CK, Kalten MR, Flynn J. Risk perception for developing diabetes: comparative risk judgments of physicians. Diabetes Care. 2003 Sep; 26(9):2543-8. PMID: 12941716.
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