Type III Secretion Systems
"Type III Secretion Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein transmembrane complexes in GRAM-NEGATIVE BACTERIA involved in either the secretion of effector proteins from the bacterial cytoplasm into host cells, or the secretion and assembly of flagellar components. The major component of the T3SSs is called the injectosome or needle complex.
Descriptor ID |
D000069296
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MeSH Number(s) |
D05.500.890.500.875
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Concept/Terms |
Type III Secretion Systems- Type III Secretion Systems
- T3SS Secretion System
- Secretion System, T3SS
- System, T3SS Secretion
- Type 3 Secretion System
- Bacterial Secretion System, Type III
- Type III Secretion System
- Type 3 Secretion Systems
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Below are MeSH descriptors whose meaning is more general than "Type III Secretion Systems".
Below are MeSH descriptors whose meaning is more specific than "Type III Secretion Systems".
This graph shows the total number of publications written about "Type III Secretion Systems" by people in this website by year, and whether "Type III Secretion Systems" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2019 | 3 | 0 | 3 | 2020 | 1 | 0 | 1 | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Type III Secretion Systems" by people in Profiles.
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Chen P, Russo BC, Duncan-Lowey JK, Bitar N, Egger KT, Goldberg MB. Topology and Contribution to the Pore Channel Lining of Plasma Membrane-Embedded Shigella flexneri Type 3 Secretion Translocase IpaB. mBio. 2021 12 21; 12(6):e0302121.
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Russo BC, Duncan-Lowey JK, Chen P, Goldberg MB. The type 3 secretion system requires actin polymerization to open translocon pores. PLoS Pathog. 2021 09; 17(9):e1009932.
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LeBlanc MA, Fink MR, Perkins TT, Sousa MC. Type III secretion system effector proteins are mechanically labile. Proc Natl Acad Sci U S A. 2021 03 23; 118(12).
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Janssen KH, Corley JM, Djapgne L, Cribbs JT, Voelker D, Slusher Z, Nordell R, Regulski EE, Kazmierczak BI, McMackin EW, Yahr TL. Hfq and sRNA 179 Inhibit Expression of the Pseudomonas aeruginosa cAMP-Vfr and Type III Secretion Regulons. mBio. 2020 06 16; 11(3).
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Russo BC, Duncan JK, Wiscovitch AL, Hachey AC, Goldberg MB. Activation of Shigella flexneri type 3 secretion requires a host-induced conformational change to the translocon pore. PLoS Pathog. 2019 11; 15(11):e1007928.
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Williams McMackin EA, Djapgne L, Corley JM, Yahr TL. Fitting Pieces into the Puzzle of Pseudomonas aeruginosa Type III Secretion System Gene Expression. J Bacteriol. 2019 07 01; 201(13).
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Russo BC, Duncan JK, Goldberg MB. Topological Analysis of the Type 3 Secretion System Translocon Pore Protein IpaC following Its Native Delivery to the Plasma Membrane during Infection. mBio. 2019 05 28; 10(3).
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Tapscott T, Kim JS, Crawford MA, Fitzsimmons L, Liu L, Jones-Carson J, V?zquez-Torres A. Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. Sci Rep. 2018 06 21; 8(1):9465.
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Tseytin I, Dagan A, Oren S, Sal-Man N. The role of EscD in supporting EscC polymerization in the type III secretion system of enteropathogenic Escherichia coli. Biochim Biophys Acta Biomembr. 2018 Feb; 1860(2):384-395.
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Young AM, Minson M, McQuate SE, Palmer AE. Optimized Fluorescence Complementation Platform for Visualizing Salmonella Effector Proteins Reveals Distinctly Different Intracellular Niches in Different Cell Types. ACS Infect Dis. 2017 08 11; 3(8):575-584.
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