 Sphingosine N-Acyltransferase
"Sphingosine N-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the acyltransferase of SPHINGOSINE to N-acylsphingosine using acyl-COENZYME A as donor and COENZYME A as acceptor. The enzyme is mainly localized in the MITOCHONDRIA.
| Descriptor ID |
D051049
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| MeSH Number(s) |
D08.811.913.050.712
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| Concept/Terms |
Sphingosine N-Acyltransferase- Sphingosine N-Acyltransferase
- N-Acyltransferase, Sphingosine
- Sphingosine N Acyltransferase
- Sphingosine Acyltransferase
- Acyltransferase, Sphingosine
- Ceramide Synthetase
- Synthetase, Ceramide
- Fatty Acyl-CoA - Sphingosine Acyltransferase
- Fatty Acyl CoA Sphingosine Acyltransferase
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Below are MeSH descriptors whose meaning is more general than "Sphingosine N-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Sphingosine N-Acyltransferase".
This graph shows the total number of publications written about "Sphingosine N-Acyltransferase" by people in this website by year, and whether "Sphingosine N-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sphingosine N-Acyltransferase" by people in Profiles.
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Mizumura K, Justice MJ, Schweitzer KS, Krishnan S, Bronova I, Berdyshev EV, Hubbard WC, Pewzner-Jung Y, Futerman AH, Choi AMK, Petrache I. Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure. FASEB J. 2018 04; 32(4):1880-1890.
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Novgorodov SA, Riley CL, Keffler JA, Yu J, Kindy MS, Macklin WB, Lombard DB, Gudz TI. SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY. J Biol Chem. 2016 Jan 22; 291(4):1957-1973.
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Petrache I, Kamocki K, Poirier C, Pewzner-Jung Y, Laviad EL, Schweitzer KS, Van Demark M, Justice MJ, Hubbard WC, Futerman AH. Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models. PLoS One. 2013; 8(5):e62968.
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Zhao L, Spassieva SD, Jucius TJ, Shultz LD, Shick HE, Macklin WB, Hannun YA, Obeid LM, Ackerman SL. A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. PLoS Genet. 2011 May; 7(5):e1002063.
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