 1-Acylglycerophosphocholine O-Acyltransferase
"1-Acylglycerophosphocholine O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transfer of long-chain fatty acids, preferentially unsaturated fatty acids, to lysophosphatides with the formation of 1,2-diacylglycero-3-phosphocholine and CoA. EC 2.3.1.23.
| Descriptor ID |
D008243
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| MeSH Number(s) |
D08.811.913.050.175
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| Concept/Terms |
1-Acylglycerophosphocholine O-Acyltransferase- 1-Acylglycerophosphocholine O-Acyltransferase
- 1 Acylglycerophosphocholine O Acyltransferase
- O-Acyltransferase, 1-Acylglycerophosphocholine
- Acyl-CoA-1-Acylglycero-3-Phosphocholine-O-Acyltransferase
- Acyl CoA 1 Acylglycero 3 Phosphocholine O Acyltransferase
- 1-Acylglycerophosphocholine Acyltransferase
- 1 Acylglycerophosphocholine Acyltransferase
- Acyltransferase, 1-Acylglycerophosphocholine
- Lysophosphatidylcholine Acyltransferase
- Acyltransferase, Lysophosphatidylcholine
- Lysophosphatidylcholine-Palmitoyl CoA Acyltransferase
- Acyltransferase, Lysophosphatidylcholine-Palmitoyl CoA
- CoA Acyltransferase, Lysophosphatidylcholine-Palmitoyl
- Lysophosphatidylcholine Palmitoyl CoA Acyltransferase
- Lysophospholipid Acyltransferase
- Acyltransferase, Lysophospholipid
- Acyl CoA Lysolecithin Acyltransferase
- Lysolecithin Acyltransferase
- Acyltransferase, Lysolecithin
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Below are MeSH descriptors whose meaning is more general than "1-Acylglycerophosphocholine O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "1-Acylglycerophosphocholine O-Acyltransferase".
This graph shows the total number of publications written about "1-Acylglycerophosphocholine O-Acyltransferase" by people in this website by year, and whether "1-Acylglycerophosphocholine O-Acyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "1-Acylglycerophosphocholine O-Acyltransferase" by people in Profiles.
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Moore A, Busch MP, Dziewulska K, Francis RO, Hod EA, Zimring JC, D'Alessandro A, Page GP. Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors. J Biol Chem. 2022 12; 298(12):102706.
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Murphy RC, Folco G. Lysophospholipid acyltransferases and leukotriene biosynthesis: intersection of the Lands cycle and the arachidonate PI cycle. J Lipid Res. 2019 02; 60(2):219-226.
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Zarini S, Hankin JA, Murphy RC, Gij?n MA. Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:52-61.
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Martin SA, Gij?n MA, Voelker DR, Murphy RC. Measurement of lysophospholipid acyltransferase activities using substrate competition. J Lipid Res. 2014 Apr; 55(4):782-91.
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Bridges JP, Ikegami M, Brilli LL, Chen X, Mason RJ, Shannon JM. LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice. J Clin Invest. 2010 May; 120(5):1736-48.
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Steinhauer J, Gij?n MA, Riekhof WR, Voelker DR, Murphy RC, Treisman JE. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec; 20(24):5224-35.
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Gij?n MA, Riekhof WR, Zarini S, Murphy RC, Voelker DR. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. J Biol Chem. 2008 Oct 31; 283(44):30235-45.
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Riekhof WR, Wu J, Gij?n MA, Zarini S, Murphy RC, Voelker DR. Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem. 2007 Dec 21; 282(51):36853-61.
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Riekhof WR, Wu J, Jones JL, Voelker DR. Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae. J Biol Chem. 2007 Sep 28; 282(39):28344-28352.
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