 Sphingolipids
"Sphingolipids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
| Descriptor ID |
D013107
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| MeSH Number(s) |
D10.570.877
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sphingolipids".
Below are MeSH descriptors whose meaning is more specific than "Sphingolipids".
This graph shows the total number of publications written about "Sphingolipids" by people in this website by year, and whether "Sphingolipids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 3 | 1 | 4 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 2 | 2 | | 2022 | 0 | 3 | 3 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sphingolipids" by people in Profiles.
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Basu SK, Prislovsky A, Lenchik N, Stephenson DJ, Agarwal R, Chalfant CE, Mandal N. Mouse Model of Nitrogen Mustard Ocular Surface Injury Characterization and Sphingolipid Signaling. Int J Mol Sci. 2024 Jan 06; 25(2).
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Zarini S, Zemski Berry KA, Kahn DE, Garfield A, Perreault L, Kerege A, Bergman BC. Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In?Vitro. Diabetes. 2023 07 01; 72(7):884-897.
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Stephenson DJ, MacKnight HP, Hoeferlin LA, Washington SL, Sawyers C, Archer KJ, Strauss JF, Walsh SW, Chalfant CE. Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy. J Lipid Res. 2023 06; 64(6):100377.
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Xia C, Suriyanarayanan S, Gong Y, Fridman V, Selig M, Li J, Rutkove S, Hornemann T, Eichler F. Long-term effects of l-serine supplementation upon a mouse model of diabetic neuropathy. J Diabetes Complications. 2023 02; 37(2):108383.
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Zarini S, Brozinick JT, Zemski Berry KA, Garfield A, Perreault L, Kerege A, Bui HH, Sanders P, Siddall P, Kuo MS, Bergman BC. Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in?vitro. J Lipid Res. 2022 10; 63(10):100270.
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Mondal K, Porter H, Cole J, Pandya HK, Basu SK, Khanam S, Chiu CY, Shah V, Stephenson DJ, Chalfant CE, Mandal N. Hydroxychloroquine Causes Early Inner Retinal Toxicity and Affects Autophagosome-Lysosomal Pathway and Sphingolipid Metabolism in the Retina. Mol Neurobiol. 2022 Jun; 59(6):3873-3887.
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Mondal K, Takahashi H, Cole J, Del Mar NA, Li C, Stephenson DJ, Allegood J, Cowart LA, Chalfant CE, Reiner A, Mandal N. Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury. Mol Neurobiol. 2021 Nov; 58(11):5564-5580.
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Broussard JL, Perreault L, Macias E, Newsom SA, Harrison K, Bui HH, Milligan P, Roth KD, Nemkov T, D'Alessandro A, Brozinick JT, Bergman BC. Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. Obesity (Silver Spring). 2021 03; 29(3):550-561.
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Walsh SW, Reep DT, Alam SMK, Washington SL, Al Dulaimi M, Lee SM, Springel EH, Strauss JF, Stephenson DJ, Chalfant CE. Placental Production of Eicosanoids and Sphingolipids in Women Who Developed Preeclampsia on Low-Dose Aspirin. Reprod Sci. 2020 12; 27(12):2158-2169.
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Callaghan BC, Gallagher G, Fridman V, Feldman EL. Diabetic neuropathy: what does the future hold? Diabetologia. 2020 05; 63(5):891-897.
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