Sphingolipids
"Sphingolipids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
Descriptor ID |
D013107
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MeSH Number(s) |
D10.570.877
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sphingolipids".
Below are MeSH descriptors whose meaning is more specific than "Sphingolipids".
This graph shows the total number of publications written about "Sphingolipids" by people in this website by year, and whether "Sphingolipids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 | 2007 | 1 | 1 | 2 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 1 | 1 | 2 | 2016 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2018 | 3 | 1 | 4 | 2019 | 1 | 1 | 2 | 2020 | 1 | 1 | 2 | 2021 | 0 | 3 | 3 | 2022 | 0 | 3 | 3 | 2023 | 0 | 3 | 3 | 2024 | 2 | 4 | 6 |
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Below are the most recent publications written about "Sphingolipids" by people in Profiles.
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Tahia F, Ma D, Stephenson DJ, Basu SK, Del Mar NA, Lenchik N, Kochat H, Brown K, Chalfant CE, Mandal N. Inhibiting De Novo Biosynthesis of Ceramide by L-Cycloserine Can Prevent Light-Induced Retinal Degeneration in Albino BALB/c Mice. Int J Mol Sci. 2024 Dec 13; 25(24).
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Broussard JL, Garfield A, Zarini S, Brozinick JT, Perreault L, Newsom SA, Kahn D, Kerege A, Berry KZ, Bui HH, Bergman BC. Combined diet and exercise training decreases serum lipids associated with insulin resistance. Obesity (Silver Spring). 2024 Dec; 32(12):2334-2344.
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Mondal K, Del Mar NA, Gary AA, Grambergs RC, Yousuf M, Tahia F, Stephenson B, Stephenson DJ, Chalfant CE, Reiner A, Mandal N. Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases. Lipids Health Dis. 2024 Jun 27; 23(1):200.
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Tahia F, Basu SK, Prislovsky A, Mondal K, Ma D, Kochat H, Brown K, Stephenson DJ, Chalfant CE, Mandal N. Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells. Exp Eye Res. 2024 May; 242:109852.
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Basu SK, Prislovsky A, Lenchik N, Stephenson DJ, Agarwal R, Chalfant CE, Mandal N. Mouse Model of Nitrogen Mustard Ocular Surface Injury Characterization and Sphingolipid Signaling. Int J Mol Sci. 2024 Jan 06; 25(2).
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Al Saedi A, Yacoub AS, Awad K, Karasik D, Brotto M, Duque G. The Interplay of Lipid Signaling in Musculoskeletal Cross Talk: Implications for Health and Disease. Methods Mol Biol. 2024; 2816:1-11.
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Gary AA, Prislovsky A, Tovar A, Locatelli E, Felix ER, Stephenson D, Chalfant CE, Lai J, Kim C, Mandal N, Galor A. Lipids from ocular meibum and tears may serve as biomarkers for depression and post-traumatic stress disorder. Clin Exp Ophthalmol. 2024 Jul; 52(5):516-527.
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Zarini S, Zemski Berry KA, Kahn DE, Garfield A, Perreault L, Kerege A, Bergman BC. Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In?Vitro. Diabetes. 2023 07 01; 72(7):884-897.
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Stephenson DJ, MacKnight HP, Hoeferlin LA, Washington SL, Sawyers C, Archer KJ, Strauss JF, Walsh SW, Chalfant CE. Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy. J Lipid Res. 2023 06; 64(6):100377.
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Xia C, Suriyanarayanan S, Gong Y, Fridman V, Selig M, Li J, Rutkove S, Hornemann T, Eichler F. Long-term effects of l-serine supplementation upon a mouse model of diabetic neuropathy. J Diabetes Complications. 2023 02; 37(2):108383.
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