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Scott Alper

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pollyea DA, Harris C, Rabe JL, Hedin BR, De Arras L, Katz S, Wheeler E, Bejar R, Walter MJ, Jordan CT, Pietras EM, Alper S. Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling. Haematologica. 2019 Mar 07. PMID: 30846499.
      View in: PubMed
    2. Alper S, Lenz LL. Editorial overview: Tuning the innate immune response to pathogens. Curr Opin Immunol. 2018 Oct; 54:vi-ix. PMID: 30342707.
      View in: PubMed
    3. Mubarak RA, Roberts N, Mason RJ, Alper S, Chu HW. Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages. Respir Res. 2018 06 25; 19(1):126. PMID: 29940963.
      View in: PubMed
    4. Honda JR, Alper S, Bai X, Chan ED. Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections. Curr Opin Immunol. 2018 Oct; 54:66-73. PMID: 29936307.
      View in: PubMed
    5. Pollyea DA, Hedin BR, O'Connor BP, Alper S. Monocyte function in patients with myelodysplastic syndrome. J Leukoc Biol. 2018 Sep; 104(3):641-647. PMID: 29656609.
      View in: PubMed
    6. Apfeld J, Alper S. What Can We Learn About Human Disease from the Nematode C. elegans? Methods Mol Biol. 2018; 1706:53-75. PMID: 29423793.
      View in: PubMed
    7. Lee FF, Alper S. Functional Genomics in Murine Macrophages. Methods Mol Biol. 2018; 1809:289-298. PMID: 29987795.
      View in: PubMed
    8. Blumhagen RZ, Hedin BR, Malcolm KC, Burnham EL, Moss M, Abraham E, Huie TJ, Nick JA, Fingerlin TE, Alper S. Alternative pre-mRNA splicing of Toll-like receptor signaling components in peripheral blood mononuclear cells from patients with ARDS. Am J Physiol Lung Cell Mol Physiol. 2017 Nov 01; 313(5):L930-L939. PMID: 28775099.
      View in: PubMed
    9. Alper S, Warg LA, De Arras L, Flatley BR, Davidson EJ, Adams J, Smith K, Wohlford-Lenane CL, McCray PB, Pedersen BS, Schwartz DA, Yang IV. Novel Innate Immune Genes Regulating the Macrophage Response to Gram Positive Bacteria. Genetics. 2016 09; 204(1):327-36. PMID: 27356610; PMCID: PMC5012397 [Available on 09/01/17].
    10. O'Connor BP, Danhorn T, De Arras L, Flatley BR, Marcus RA, Farias-Hesson E, Leach SM, Alper S. Regulation of toll-like receptor signaling by the SF3a mRNA splicing complex. PLoS Genet. 2015 Feb; 11(2):e1004932. PMID: 25658809.
      View in: PubMed
    11. De Arras L, Guthrie BS, Alper S. Using RNA-interference to investigate the innate immune response in mouse macrophages. J Vis Exp. 2014 Nov 03; (93):e51306. PMID: 25407484.
      View in: PubMed
    12. De Arras L, Laws R, Leach SM, Pontis K, Freedman JH, Schwartz DA, Alper S. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. Genetics. 2014 Jun; 197(2):485-96. PMID: 24361939; PMCID: PMC4063909.
    13. De Arras L, Alper S. Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing. PLoS Genet. 2013 Oct; 9(10):e1003855. PMID: 24204290; PMCID: PMC3812059.
    14. Victorino F, Alper S. Identifying novel spatiotemporal regulators of innate immunity. Immunol Res. 2013 Mar; 55(1-3):3-9. PMID: 22926826; PMCID: PMC3921965.
    15. De Arras L, Seng A, Lackford B, Keikhaee MR, Bowerman B, Freedman JH, Schwartz DA, Alper S. An evolutionarily conserved innate immunity protein interaction network. J Biol Chem. 2013 Jan 18; 288(3):1967-78. PMID: 23209288; PMCID: PMC3548504.
    16. De Arras L, Yang IV, Lackford B, Riches DW, Prekeris R, Freedman JH, Schwartz DA, Alper S. Spatiotemporal inhibition of innate immunity signaling by the Tbc1d23 RAB-GAP. J Immunol. 2012 Mar 15; 188(6):2905-13. PMID: 22312129; PMCID: PMC3293945.
    17. Yang IV, Jiang W, Rutledge HR, Lackford B, Warg LA, De Arras L, Alper S, Schwartz DA, Pisetsky DS. Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. Mol Immunol. 2011 Sep; 48(15-16):1886-95. PMID: 21665277.
      View in: PubMed
    18. Yang IV, Alper S, Lackford B, Rutledge H, Warg LA, Burch LH, Schwartz DA. Novel regulators of the systemic response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):393-402. PMID: 21131441; PMCID: PMC3175565.
    19. Alper S. Model systems to the rescue: The relationship between aging and innate immunity. Commun Integr Biol. 2010 Sep; 3(5):409-14. PMID: 21057627; PMCID: PMC2974067.
    20. Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA. The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem. 2010 Jan 15; 285(3):1822-8. PMID: 19923212; PMCID: PMC2804340.
    21. Yang IV, Wade CM, Kang HM, Alper S, Rutledge H, Lackford B, Eskin E, Daly MJ, Schwartz DA. Identification of novel genes that mediate innate immunity using inbred mice. Genetics. 2009 Dec; 183(4):1535-44. PMID: 19805818; PMCID: PMC2787437.
    22. Green RM, Gally F, Keeney JG, Alper S, Gao B, Han M, Martin RJ, Weinberger AR, Case SR, Minor MN, Chu HW. Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. PLoS One. 2009 Aug 31; 4(8):e6860. PMID: 19718433; PMCID: PMC2729919.
    23. Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):7016-21. PMID: 18463287; PMCID: PMC2383967.
    24. Alper S, Podbilewicz B. Cell fusion in Caenorhabditis elegans. Methods Mol Biol. 2008; 475:53-74. PMID: 18979238.
      View in: PubMed
    25. Alper S, McBride SJ, Lackford B, Freedman JH, Schwartz DA. Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol. 2007 Aug; 27(15):5544-53. PMID: 17526726.
      View in: PubMed
    26. Cui Y, McBride SJ, Boyd WA, Alper S, Freedman JH. Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Genome Biol. 2007; 8(6):R122. PMID: 17592649; PMCID: PMC2394766.
    27. Alper S, Kenyon C. The zinc finger protein REF-2 functions with the Hox genes to inhibit cell fusion in the ventral epidermis of C. elegans. Development. 2002 Jul; 129(14):3335-48. PMID: 12091304.
      View in: PubMed
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