 Receptors, Nicotinic
"Receptors, Nicotinic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
| Descriptor ID |
D011978
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| MeSH Number(s) |
D12.776.157.530.400.400.100.500 D12.776.543.550.450.500.100.500 D12.776.543.585.400.500.100.500 D12.776.543.750.130.687 D12.776.543.750.720.360.550
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| Concept/Terms |
Receptors, Nicotinic- Receptors, Nicotinic
- Nicotinic Receptors
- Nicotinic Acetylcholine Receptors
- Acetylcholine Receptors, Nicotinic
- Receptors, Nicotinic Acetylcholine
- Nicotinic Acetylcholine Receptor
- Acetylcholine Receptor, Nicotinic
- Receptor, Nicotinic Acetylcholine
- Nicotinic Receptor
- Receptor, Nicotinic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Nicotinic".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Nicotinic".
This graph shows the total number of publications written about "Receptors, Nicotinic" by people in this website by year, and whether "Receptors, Nicotinic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 1 | 4 | | 2000 | 7 | 1 | 8 | | 2001 | 5 | 2 | 7 | | 2002 | 8 | 1 | 9 | | 2003 | 6 | 4 | 10 | | 2004 | 4 | 0 | 4 | | 2005 | 4 | 1 | 5 | | 2006 | 1 | 1 | 2 | | 2007 | 11 | 1 | 12 | | 2008 | 7 | 3 | 10 | | 2009 | 8 | 3 | 11 | | 2010 | 12 | 1 | 13 | | 2011 | 9 | 2 | 11 | | 2012 | 11 | 2 | 13 | | 2013 | 6 | 2 | 8 | | 2014 | 3 | 1 | 4 | | 2015 | 7 | 3 | 10 | | 2016 | 4 | 0 | 4 | | 2017 | 2 | 4 | 6 | | 2018 | 5 | 0 | 5 | | 2019 | 1 | 1 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 4 | 1 | 5 | | 2022 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Nicotinic" by people in Profiles.
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Quijano Cardé NA, Shaw J, Carter C, Kim S, Stitzel JA, Venkatesh SK, Ramchandani VA, De Biasi M. Mutation of the a5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption. Neuropharmacology. 2022 09 15; 216:109170.
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Rahman MM, Basta T, Teng J, Lee M, Worrell BT, Stowell MHB, Hibbs RE. Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat Struct Mol Biol. 2022 04; 29(4):386-394.
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Routhier J, Pons S, Freidja ML, Dalstein V, Cutrona J, Jonquet A, Lalun N, Mérol JC, Lathrop M, Stitzel JA, Kervoaze G, Pichavant M, Gosset P, Tournier JM, Birembaut P, Dormoy V, Maskos U. An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions. Nat Commun. 2021 11 04; 12(1):6384.
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Buck JM, O'Neill HC, Stitzel JA. The Intergenerational Transmission of Developmental Nicotine Exposure-Induced Neurodevelopmental Disorder-Like Phenotypes is Modulated by the Chrna5 D397N Polymorphism in Adolescent Mice. Behav Genet. 2021 11; 51(6):665-684.
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Adjangba C, Border R, Romero Villela PN, Ehringer MA, Evans LM. Little Evidence of Modified Genetic Effect of rs16969968 on Heavy Smoking Based on Age of Onset of Smoking. Nicotine Tob Res. 2021 05 24; 23(6):1055-1063.
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Minguez-Viñas T, Nielsen BE, Shoemark DK, Gotti C, Sessions RB, Mulholland AJ, Bouzat C, Wonnacott S, Gallagher T, Bermudez I, Oliveira AS. A conserved arginine with non-conserved function is a key determinant of agonist selectivity in a7 nicotinic ACh receptors. Br J Pharmacol. 2021 04; 178(7):1651-1668.
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Rahman MM, Worrell BT, Stowell MHB, Hibbs RE. Purification of a native nicotinic receptor. Methods Enzymol. 2021; 653:189-206.
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Bray MJ, Chen LS, Fox L, Hancock DB, Culverhouse RC, Hartz SM, Johnson EO, Liu M, McKay JD, Saccone NL, Hokanson JE, Vrieze SI, Tyndale RF, Baker TB, Bierut LJ. Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme. Genet Epidemiol. 2020 10; 44(7):748-758.
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Nielsen BE, Stabile S, Vitale C, Bouzat C. Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of a7 Nicotinic Acetylcholine Receptors. ACS Chem Neurosci. 2020 09 02; 11(17):2688-2704.
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Evans LM, Johnson EC, Melroy-Greif WE, Hewitt JK, Hoeffer CA, Keller MC, Saba LM, Stitzel JA, Ehringer MA. The Role of A Priori-Identified Addiction and Smoking Gene Sets in Smoking Behaviors. Nicotine Tob Res. 2020 07 16; 22(8):1310-1315.
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