 Receptors, Nicotinic
"Receptors, Nicotinic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
| Descriptor ID |
D011978
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| MeSH Number(s) |
D12.776.157.530.400.400.100.500 D12.776.543.550.425.500.100.500 D12.776.543.585.400.500.100.500 D12.776.543.750.051.687 D12.776.543.750.720.360.550
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| Concept/Terms |
Receptors, Nicotinic- Receptors, Nicotinic
- Nicotinic Acetylcholine Receptors
- Acetylcholine Receptors, Nicotinic
- Receptors, Nicotinic Acetylcholine
- Nicotinic Receptors
- Nicotinic Acetylcholine Receptor
- Acetylcholine Receptor, Nicotinic
- Receptor, Nicotinic Acetylcholine
- Nicotinic Receptor
- Receptor, Nicotinic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Nicotinic".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.425.500.100]
- Receptors, Nicotinic [D12.776.543.550.425.500.100.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.051]
- Receptors, Nicotinic [D12.776.543.750.051.687]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Nicotinic".
This graph shows the total number of publications written about "Receptors, Nicotinic" by people in this website by year, and whether "Receptors, Nicotinic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 2 | 0 | 2 | | 1987 | 0 | 1 | 1 | | 1989 | 3 | 0 | 3 | | 1990 | 6 | 2 | 8 | | 1991 | 1 | 1 | 2 | | 1992 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 2 | 5 | | 1999 | 3 | 1 | 4 | | 2000 | 8 | 1 | 9 | | 2001 | 5 | 2 | 7 | | 2002 | 9 | 1 | 10 | | 2003 | 6 | 6 | 12 | | 2004 | 4 | 0 | 4 | | 2005 | 5 | 3 | 8 | | 2006 | 2 | 1 | 3 | | 2007 | 12 | 1 | 13 | | 2008 | 8 | 3 | 11 | | 2009 | 9 | 4 | 13 | | 2010 | 13 | 2 | 15 | | 2011 | 10 | 0 | 10 | | 2012 | 15 | 3 | 18 | | 2013 | 8 | 2 | 10 | | 2014 | 4 | 1 | 5 | | 2015 | 8 | 4 | 12 | | 2016 | 4 | 0 | 4 | | 2017 | 3 | 4 | 7 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Nicotinic" by people in Profiles.
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Parker RL, O'Neill HC, Henley BM, Wageman CR, Drenan RM, Marks MJ, Miwa JM, Grady SR, Lester HA. Deletion of lynx1 reduces the function of a6* nicotinic receptors. PLoS One. 2017; 12(12):e0188715.
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Bai X, Stitzel JA, Bai A, Zambrano CA, Phillips M, Marrack P, Chan ED. Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis. Am J Respir Cell Mol Biol. 2017 09; 57(3):324-333.
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Fait BW, Thompson DC, Mose TN, Jatlow P, Jordt SE, Picciotto MR, Mineur YS. Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice. Behav Brain Res. 2017 09 15; 334:72-77.
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Kamens HM, Silva C, McCarthy R, Cox RJ, Ehringer MA. No evidence of a role of the ß4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors. BMC Res Notes. 2017 Apr 05; 10(1):151.
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Melroy-Greif WE, Simonson MA, Corley RP, Lutz SM, Hokanson JE, Ehringer MA. Examination of the Involvement of Cholinergic-Associated Genes in Nicotine Behaviors in European and African Americans. Nicotine Tob Res. 2017 Apr 01; 19(4):417-425.
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Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. J Psychopharmacol. 2017 04; 31(4):434-441.
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Koukouli F, Rooy M, Tziotis D, Sailor KA, O'Neill HC, Levenga J, Witte M, Nilges M, Changeux JP, Hoeffer CA, Stitzel JA, Gutkin BS, DiGregorio DA, Maskos U. Nicotine reverses hypofrontality in animal models of addiction and schizophrenia. Nat Med. 2017 Mar; 23(3):347-354.
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McClure-Begley TD, Esterlis I, Stone KL, Lam TT, Grady SR, Colangelo CM, Lindstrom JM, Marks MJ, Picciotto MR. Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex. eNeuro. 2016 Jul-Aug; 3(4).
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Chen LS, Baker T, Hung RJ, Horton A, Culverhouse R, Hartz S, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Rosenberger A, Aben KK, Andrew AS, Chang SC, Saum KU, Dienemann H, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden EH, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Brüske I, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare MD, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Amos CI, Bierut LJ. Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis. EBioMedicine. 2016 Sep; 11:219-226.
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Ondachi PW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues. ACS Chem Neurosci. 2016 07 20; 7(7):1004-12.
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