 S-Adenosylhomocysteine
"S-Adenosylhomocysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
| Descriptor ID |
D012435
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| MeSH Number(s) |
D02.886.030.498.050 D03.633.100.759.590.138.240 D12.125.166.498.050 D13.570.583.138.240 D13.570.800.096.262
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "S-Adenosylhomocysteine".
Below are MeSH descriptors whose meaning is more specific than "S-Adenosylhomocysteine".
This graph shows the total number of publications written about "S-Adenosylhomocysteine" by people in this website by year, and whether "S-Adenosylhomocysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 3 | 1 | 4 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "S-Adenosylhomocysteine" by people in Profiles.
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Stabler SP. Alterations in Sulfur Amino Acids as Biomarkers of Disease. J Nutr. 2020 10 01; 150(Suppl 1):2532S-2537S.
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Kharbanda KK, Todero SL, Thomes PG, Orlicky DJ, Osna NA, French SW, Tuma DJ. Increased methylation demand exacerbates ethanol-induced liver injury. Exp Mol Pathol. 2014 Aug; 97(1):49-56.
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Klepacki J, Brunner N, Schmitz V, Klawitter J, Christians U, Klawitter J. Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma. Clin Chim Acta. 2013 Jun 05; 421:91-7.
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Edwards AL, Reyes FE, Héroux A, Batey RT. Structural basis for recognition of S-adenosylhomocysteine by riboswitches. RNA. 2010 Nov; 16(11):2144-55.
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Stabler SP, Sekhar J, Allen RH, O'Neill HC, White CW. Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. Free Radic Biol Med. 2009 Oct 15; 47(8):1147-53.
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Lopreato FR, Stabler SP, Carvalho FR, Hirata RD, Hirata MH, Robi DL, Sampaio-Neto LF, Allen RH, Guerra-Shinohara EM. Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. Clin Chim Acta. 2008 Dec; 398(1-2):134-9.
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Barbosa PR, Stabler SP, Trentin R, Carvalho FR, Luchessi AD, Hirata RD, Hirata MH, Allen RH, Guerra-Shinohara EM. Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women. Clin Chim Acta. 2008 Feb; 388(1-2):139-47.
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Barbosa PR, Stabler SP, Machado AL, Braga RC, Hirata RD, Hirata MH, Sampaio-Neto LF, Allen RH, Guerra-Shinohara EM. Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women. Eur J Clin Nutr. 2008 Aug; 62(8):1010-21.
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Guerra-Shinohara EM, Morita OE, Pagliusi RA, Blaia-d'Avila VL, Allen RH, Stabler SP. Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia. Metabolism. 2007 Mar; 56(3):339-47.
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Mudd SH, Brosnan JT, Brosnan ME, Jacobs RL, Stabler SP, Allen RH, Vance DE, Wagner C. Methyl balance and transmethylation fluxes in humans. Am J Clin Nutr. 2007 Jan; 85(1):19-25.
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