 Choline
"Choline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
| Descriptor ID |
D002794
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| MeSH Number(s) |
D02.033.100.291.211 D02.092.063.291.211 D02.092.877.883.333 D02.675.276.232
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| Concept/Terms |
Choline- Choline
- 2-Hydroxy-N,N,N-trimethylethanaminium
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Below are MeSH descriptors whose meaning is more general than "Choline".
Below are MeSH descriptors whose meaning is more specific than "Choline".
This graph shows the total number of publications written about "Choline" by people in this website by year, and whether "Choline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1995 | 1 | 1 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 3 | 5 | 8 | | 2007 | 3 | 0 | 3 | | 2008 | 4 | 0 | 4 | | 2009 | 0 | 3 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 2 | 1 | 3 | | 2012 | 2 | 2 | 4 | | 2013 | 2 | 3 | 5 | | 2014 | 2 | 3 | 5 | | 2015 | 1 | 2 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 1 | 3 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Choline" by people in Profiles.
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Hunter SK, Hoffman MC, D'Alessandro A, Walker VK, Balser M, Noonan K, Law AJ, Freedman R. Maternal prenatal choline and inflammation effects on 4-year-olds' performance on the Wechsler Preschool and Primary Scale of Intelligence-IV. J Psychiatr Res. 2021 09; 141:50-56.
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Hoffman MC, Freedman R, Law AJ, Clark AM, Hunter SK. Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development. Clin Nutr ESPEN. 2021 06; 43:1-8.
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Ebert T, Painer J, Bergman P, Qureshi AR, Giroud S, Stalder G, Kublickiene K, Göritz F, Vetter S, Bieber C, Fröbert O, Arnemo JM, Zedrosser A, Redtenbacher I, Shiels PG, Johnson RJ, Stenvinkel P. Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears. Sci Rep. 2020 11 23; 10(1):20323.
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Freedman R, Hunter SK, Law AJ, D'Alessandro A, Noonan K, Wyrwa A, Camille Hoffman M. Maternal choline and respiratory coronavirus effects on fetal brain development. J Psychiatr Res. 2020 09; 128:1-4.
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Hunter SK, Hoffman MC, D'Alessandro A, Noonan K, Wyrwa A, Freedman R, Law AJ. Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development. Psychol Med. 2021 02; 51(3):450-459.
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Hoffman MC, Hunter SK, D'Alessandro A, Noonan K, Wyrwa A, Freedman R. Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring. Psychol Med. 2020 07; 50(10):1716-1726.
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Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC. Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development. J Pediatr. 2019 05; 208:198-206.e2.
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Alakkas A, Ellis RJ, Watson CW, Umlauf A, Heaton RK, Letendre S, Collier A, Marra C, Clifford DB, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Kallianpur A, Gianella S, Marcotte T, Grant I, Fennema-Notestine C. White matter damage, neuroinflammation, and neuronal integrity in HAND. J Neurovirol. 2019 02; 25(1):32-41.
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Wankhade UD, Zhong Y, Kang P, Alfaro M, Chintapalli SV, Thakali KM, Shankar K. Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations. PLoS One. 2017; 12(4):e0175675.
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Jacobs RL, Jiang H, Kennelly JP, Orlicky DJ, Allen RH, Stabler SP, Maclean KN. Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria. Mol Genet Metab. 2017 04; 120(4):325-336.
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