 DNA Breaks, Double-Stranded
"DNA Breaks, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.
| Descriptor ID |
D053903
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| MeSH Number(s) |
G05.200.210.220
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| Concept/Terms |
DNA Breaks, Double-Stranded- DNA Breaks, Double-Stranded
- Break, Double-Stranded DNA
- Breaks, Double-Stranded DNA
- DNA Break, Double-Stranded
- DNA Breaks, Double Stranded
- Double-Stranded DNA Break
- Double Stranded DNA Break
- Double-Strand DNA Breaks
- Break, Double-Strand DNA
- Breaks, Double-Strand DNA
- DNA Break, Double-Strand
- DNA Breaks, Double-Strand
- Double Strand DNA Breaks
- Double-Strand DNA Break
- Double-Stranded DNA Breaks
- Double Stranded DNA Breaks
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Below are MeSH descriptors whose meaning is more general than "DNA Breaks, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "DNA Breaks, Double-Stranded".
This graph shows the total number of publications written about "DNA Breaks, Double-Stranded" by people in this website by year, and whether "DNA Breaks, Double-Stranded" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2006 | 0 | 1 | 1 | | 2008 | 1 | 4 | 5 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 1 | 3 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 1 | 2 | | 2023 | 2 | 0 | 2 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Breaks, Double-Stranded" by people in Profiles.
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Affandi T, Haas A, Ohm AM, Wright GM, Black JC, Reyland ME. PKCd Regulates Chromatin Remodeling and DNA Repair through SIRT6. Mol Cancer Res. 2024 02 01; 22(2):181-196.
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Arnoult N. Meet the authors: Nausica Arnoult. Mol Cell. 2023 05 04; 83(9):1369-1371.
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Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcal? K, Ball K, Proctor B, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Mol Cell. 2023 05 04; 83(9):1429-1445.e8.
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Abdelazeem KNM, Kalo MZ, Beer-Hammer S, Lang F. The gut microbiota metabolite urolithin A inhibits NF-?B activation in LPS stimulated BMDMs. Sci Rep. 2021 03 29; 11(1):7117.
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Affandi T, Ohm AM, Gaillard D, Haas A, Reyland ME. Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double-strand break repair. J Biol Chem. 2021 Jan-Jun; 296:100401.
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Gaullier G, Roberts G, Muthurajan UM, Bowerman S, Rudolph J, Mahadevan J, Jha A, Rae PS, Luger K. Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1. PLoS One. 2020; 15(11):e0240932.
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Choudhury A, Fankhauser RG, Freed EF, Oh EJ, Morgenthaler AB, Bassalo MC, Copley SD, Kaar JL, Gill RT. Determinants for Efficient Editing with Cas9-Mediated Recombineering in Escherichia coli. ACS Synth Biol. 2020 May 15; 9(5):1083-1099.
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Manickavinayaham S, V?lez-Cruz R, Biswas AK, Bedford E, Klein BJ, Kutateladze TG, Liu B, Bedford MT, Johnson DG. E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair. Nat Commun. 2019 10 30; 10(1):4951.
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Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K. CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. Life Sci Alliance. 2019 Jun; 2(3).
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Estrem C, Moore JK. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Mol Biol Cell. 2019 07 22; 30(16):2000-2013.
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