 A549 Cells
"A549 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.
| Descriptor ID |
D000072283
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| MeSH Number(s) |
A11.251.210.190.080 A11.251.860.180.080 A11.436.054
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| Concept/Terms |
A549 Cells- A549 Cells
- A549 Cell
- Cell, A549
- Cells, A549
- A549 Cell Line
- A549 Cell Lines
- Cell Line, A549
- Cell Lines, A549
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Below are MeSH descriptors whose meaning is more general than "A549 Cells".
Below are MeSH descriptors whose meaning is more specific than "A549 Cells".
This graph shows the total number of publications written about "A549 Cells" by people in this website by year, and whether "A549 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 4 | 4 | | 2017 | 0 | 9 | 9 | | 2018 | 0 | 7 | 7 | | 2019 | 0 | 9 | 9 | | 2020 | 0 | 8 | 8 | | 2021 | 0 | 4 | 4 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 3 | 3 | | 2025 | 0 | 5 | 5 |
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Below are the most recent publications written about "A549 Cells" by people in Profiles.
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Necker-Brown A, Mostafa MM, Georgescu A, Thorne AJ, Chandramohan P, Kooi C, Kalyanaraman K, Gao A, Bansal A, Sasse SK, Gerber AN, Leigh R, Newton R. Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-?B. PLoS One. 2025; 20(12):e0329244.
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RodrÃguez RA, Sangsanont J, Linden KG. Mechanistic Insights into Adenovirus Resistance to UV: Dose-Dependent Repair and Delayed Suppression of Host DNA Damage Response. Environ Sci Technol. 2025 Dec 16; 59(49):26830-26839.
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Thorne AJ, Gao A, Necker-Brown A, Bansal A, Kalyanaraman K, Chandramohan P, Sasse SK, Gerber AN, Mostafa MM, Newton R. Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid. Mol Pharmacol. 2025 Oct; 107(10):100073.
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Stein CS, Linzer CR, Heer CD, Witmer NH, Cochran JD, Spitz DR, Boudreau RL. Mitoregulin Promotes Cell Cycle Progression in Non-Small Cell Lung Cancer Cells. Int J Mol Sci. 2025 Feb 24; 26(5).
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Smith C, Curtis K, Bonham A, Boyer S, Lenz L, Weinberg A. Comparison of immune responses to respiratory syncytial virus in infancy, childhood, and adulthood using an in vitro model of human respiratory infection. Immunohorizons. 2025 01 24; 9(2).
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Gu W, Li H, Sun L, Shen Z, Wang Y, Hu X, Wu Y, Liu W, Wan CC, Cai Y, Yan T. The RNA-binding protein CMSS1 promotes the progression of non-small cell lung cancer by regulating the telomerase protein subunit hTERT. Life Sci. 2025 Jan 15; 361:123321.
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Necker-Brown A, Kooi C, Thorne AJ, Bansal A, Mostafa MM, Chandramohan P, Gao A, Kalyanaraman K, Milani A, Gill S, Georgescu A, Sasse SK, Gerber AN, Leigh R, Newton R. Inducible gene expression of I?B-kinase e is dependent on nuclear factor-?B in human pulmonary epithelial cells. Biochem J. 2024 07 17; 481(14):959-980.
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Kishimoto S, Crooks DR, Yasunori O, Kota Y, Yamamoto K, Linehan WM, Levine M, Krishna MC, Brender JR. Pharmacologic ascorbate induces transient hypoxia sensitizing pancreatic ductal adenocarcinoma to a hypoxia activated prodrug. Free Radic Biol Med. 2024 Sep; 222:579-587.
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Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME. Metabolic reprogramming contributes to radioprotection by protein kinase Cd. J Biol Chem. 2023 10; 299(10):105186.
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Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity. Nat Commun. 2021 10 01; 12(1):5772.
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