 Granulosa Cells
"Granulosa Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).
| Descriptor ID |
D006107
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| MeSH Number(s) |
A05.360.319.114.630.535.200 A06.407.312.497.535.300 A11.382.812 A11.436.329
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| Concept/Terms |
Granulosa Cells- Granulosa Cells
- Cell, Granulosa
- Cells, Granulosa
- Granulosa Cell
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Below are MeSH descriptors whose meaning is more general than "Granulosa Cells".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cells".
This graph shows the total number of publications written about "Granulosa Cells" by people in this website by year, and whether "Granulosa Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 3 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Granulosa Cells" by people in Profiles.
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Clark ZL, Ruebel ML, Schall PZ, Karl KR, Ireland JJ, Latham KE. Follicular Hyperstimulation Dysgenesis: New Explanation for Adverse Effects of Excessive FSH in Ovarian Stimulation. Endocrinology. 2022 09 01; 163(9).
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Llerena Cari E, Hagen-Lillevik S, Giornazi A, Post M, Komar AA, Appiah L, Bitler B, Polotsky AJ, Santoro N, Kieft J, Lai K, Johnson J. Integrated stress response control of granulosa cell translation and proliferation during normal ovarian follicle development. Mol Hum Reprod. 2021 08 07; 27(8).
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Lyngdoh EL, Nayan V, Vashisht M, Kumari S, Bhardwaj A, Bhatia T, Dalal J, Pawaria S, Onteru SK, Sikka P, Singh D. Gold nanoparticles modulate the steroidogenic and apoptotic pathway in a buffalo granulosa cell model. Biotechnol Lett. 2020 Aug; 42(8):1383-1395.
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Simon LE, Liu Z, Bousfield GR, Kumar TR, Duncan FE. Recombinant FSH glycoforms are bioactive in mouse preantral ovarian follicles. Reproduction. 2019 12; 158(6):517-527.
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Roy S, Gandra D, Seger C, Biswas A, Kushnir VA, Gleicher N, Kumar TR, Sen A. Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. Endocrinology. 2018 09 01; 159(9):3433-3445.
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Vashisht M, Rani P, Onteru SK, Singh D. Curcumin primed exosomes reverses LPS-induced pro-inflammatory gene expression in buffalo granulosa cells. J Cell Biochem. 2018 02; 119(2):1488-1500.
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Sun L, Li D, Song K, Wei J, Yao S, Li Z, Su X, Ju X, Chao L, Deng X, Kong B, Li L. Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro. Sci Rep. 2017 05 31; 7(1):2552.
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Uslu B, Dioguardi CC, Haynes M, Miao DQ, Kurus M, Hoffman G, Johnson J. Quantifying growing versus non-growing ovarian follicles in the mouse. J Ovarian Res. 2017 Jan 13; 10(1):3.
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Ruebel M, Shankar K, Gaddy D, Lindsey F, Badger T, Andres A. Maternal obesity is associated with ovarian inflammation and upregulation of early growth response factor 1. Am J Physiol Endocrinol Metab. 2016 07 01; 311(1):E269-77.
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Conca Dioguardi C, Uslu B, Haynes M, Kurus M, Gul M, Miao DQ, De Santis L, Ferrari M, Bellone S, Santin A, Giulivi C, Hoffman G, Usdin K, Johnson J. Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency. Mol Hum Reprod. 2016 06; 22(6):384-96.
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