Sertoli Cells
"Sertoli Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
Descriptor ID |
D012708
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MeSH Number(s) |
A05.360.444.849.789 A11.382.952 A11.436.837
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sertoli Cells".
Below are MeSH descriptors whose meaning is more specific than "Sertoli Cells".
This graph shows the total number of publications written about "Sertoli Cells" by people in this website by year, and whether "Sertoli Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1997 | 2 | 1 | 3 | 2002 | 1 | 1 | 2 | 2003 | 4 | 1 | 5 | 2004 | 1 | 1 | 2 | 2010 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2016 | 0 | 2 | 2 | 2017 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sertoli Cells" by people in Profiles.
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Liu Z, Wang H, Larsen M, Gunewardana S, Cendali FI, Reisz JA, Akiyama H, Behringer RR, Ma Q, Hammoud SS, Kumar TR. The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells. Mol Cell Endocrinol. 2022 06 01; 549:111641.
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Yokonishi T, McKey J, Ide S, Capel B. Sertoli cell ablation and replacement of the spermatogonial niche in mouse. Nat Commun. 2020 01 02; 11(1):40.
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Panneerdoss S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Timilsina S, Mohammad TA, Chen Y, Drake M, Vuori K, Kumar TR, Rao MK. Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells. Nat Commun. 2017 09 19; 8(1):598.
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Okayama Y, Wakui S, Wempe MF, Sugiyama M, Motohashi M, Mutou T, Takahashi H, Kume E, Ikegami H. In Utero Exposure to Di( n-butyl)phthalate Induces Morphological and Biochemical Changes in Rats Postpuberty. Toxicol Pathol. 2017 06; 45(4):526-535.
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Davis S, Lahlou N, Bardsley M, Temple MC, Kowal K, Pyle L, Zeitler P, Ross J. Gonadal function is associated with cardiometabolic health in pre-pubertal boys with Klinefelter syndrome. Andrology. 2016 11; 4(6):1169-1177.
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Li N, Mruk DD, Tang EI, Lee WM, Wong CK, Cheng CY. Formin 1 Regulates Microtubule and F-Actin Organization to Support Spermatid Transport During Spermatogenesis in the Rat Testis. Endocrinology. 2016 07; 157(7):2894-908.
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Guillermet-Guibert J, Smith LB, Halet G, Whitehead MA, Pearce W, Rebourcet D, Le?n K, Cr?pieux P, Nock G, Str?mstedt M, Enerback M, Chelala C, Graupera M, Carroll J, Cosulich S, Saunders PT, Huhtaniemi I, Vanhaesebroeck B. Novel Role for p110? PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells. PLoS Genet. 2015 Jul; 11(7):e1005304.
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Goldstein SA, Hoffenberg EJ. Peutz-Jegher syndrome in childhood: need for updated recommendations? J Pediatr Gastroenterol Nutr. 2013 Feb; 56(2):191-5.
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Panneerdoss S, Chang YF, Buddavarapu KC, Chen HI, Shetty G, Wang H, Chen Y, Kumar TR, Rao MK. Androgen-responsive microRNAs in mouse Sertoli cells. PLoS One. 2012; 7(7):e41146.
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Kumar TR. The "Glow"rious Sertoli and germ cells: mouse testis development visualized in multi-colors. Biol Reprod. 2011 Feb; 84(2):201-4.
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