PC12 Cells
"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
Descriptor ID |
D016716
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MeSH Number(s) |
A11.251.210.190.750 A11.251.860.180.750 A11.299.500
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Concept/Terms |
PC12 Cells- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
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Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
This graph shows the total number of publications written about "PC12 Cells" by people in this website by year, and whether "PC12 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 0 | 2 | 2 | 1998 | 0 | 1 | 1 | 1999 | 0 | 4 | 4 | 2000 | 0 | 2 | 2 | 2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 1 | 1 | 2 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2010 | 0 | 3 | 3 | 2013 | 0 | 1 | 1 | 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "PC12 Cells" by people in Profiles.
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Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fern?ndez-Rodriguez J, Blanco I, Castellanos E, Carri? M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021 02 11; 11(1):3661.
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Lynch KJ, Skalli O, Sabri F. Investigation of surface topography and stiffness on adhesion and neurites extension of PC12 cells on crosslinked silica aerogel substrates. PLoS One. 2017; 12(10):e0185978.
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Yu H, Rathore SS, Gulbranson DR, Shen J. The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulation. J Biol Chem. 2014 Sep 12; 289(37):25571-80.
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Larson BT, Sochacki KA, Kindem JM, Taraska JW. Systematic spatial mapping of proteins at exocytic and endocytic structures. Mol Biol Cell. 2014 Jul 01; 25(13):2084-93.
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Ari C, Borysov SI, Wu J, Padmanabhan J, Potter H. Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function. Neurobiol Aging. 2014 Aug; 35(8):1839-49.
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Yun D, Famili A, Lee YM, Jenkins PM, Freed CR, Park D. Biomimetic poly(serinol hexamethylene urea) for promotion of neurite outgrowth and guidance. J Biomater Sci Polym Ed. 2014; 25(4):354-69.
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Chu H, Johnson NR, Mason NS, Wang Y. A [polycation:heparin] complex releases growth factors with enhanced bioactivity. J Control Release. 2011 Mar 10; 150(2):157-63.
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Coultrap SJ, Buard I, Kulbe JR, Dell'Acqua ML, Bayer KU. CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin. J Biol Chem. 2010 Jun 04; 285(23):17930-7.
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Crooks KR, Kleven DT, Rodriguiz RM, Wetsel WC, McNamara JO. TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology. 2010 Jun; 58(7):1067-77.
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Soderquist RG, Milligan ED, Sloane EM, Harrison JA, Douvas KK, Potter JM, Hughes TS, Chavez RA, Johnson K, Watkins LR, Mahoney MJ. PEGylation of brain-derived neurotrophic factor for preserved biological activity and enhanced spinal cord distribution. J Biomed Mater Res A. 2009 Dec; 91(3):719-29.
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