THP-1 Cells
"THP-1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.
Descriptor ID |
D000074084
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MeSH Number(s) |
A11.251.210.190.815 A11.251.860.180.815
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Concept/Terms |
THP-1 Cells- THP-1 Cells
- Cell, THP-1
- Cells, THP-1
- THP 1 Cells
- THP-1 Cell
- THP-1 Cell Line
- Cell Line, THP-1
- Cell Lines, THP-1
- THP 1 Cell Line
- THP-1 Cell Lines
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Below are MeSH descriptors whose meaning is more general than "THP-1 Cells".
Below are MeSH descriptors whose meaning is more specific than "THP-1 Cells".
This graph shows the total number of publications written about "THP-1 Cells" by people in this website by year, and whether "THP-1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 1 | 1 | 2018 | 0 | 4 | 4 | 2019 | 0 | 2 | 2 | 2020 | 0 | 3 | 3 | 2021 | 0 | 3 | 3 | 2024 | 0 | 1 | 1 | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "THP-1 Cells" by people in Profiles.
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Collins-McMillen D, De Oliveira Pessoa D, Zarrella K, Parkins CJ, Daily M, McKinzey DR, Moorman NJ, Kamil JP, Caposio P, Padi M, Goodrum FD. Viral and host network analysis of the human cytomegalovirus transcriptome in latency. Proc Natl Acad Sci U S A. 2025 Jun 03; 122(22):e2416114122.
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Bai X, Gao J, Guan X, Narum DE, Fornis LB, Griffith DE, Gao B, Sandhaus RA, Huang H, Chan ED. Analysis of alpha-1-antitrypsin (AAT)-regulated, glucocorticoid receptor-dependent genes in macrophages reveals a novel host defense function of AAT. Physiol Rep. 2024 Jul; 12(14):e16124.
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Briaud P, Frey A, Marino EC, Bastock RA, Zielinski RE, Wiemels RE, Keogh RA, Murphy ER, Shaw LN, Carroll RK. Temperature Influences the Composition and Cytotoxicity of Extracellular Vesicles in Staphylococcus aureus. mSphere. 2021 10 27; 6(5):e0067621.
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Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity. Nat Commun. 2021 10 01; 12(1):5772.
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Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS. IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. Front Immunol. 2021; 12:713304.
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Moghbeli K, Valenzi E, Naramore R, Sembrat JC, Chen K, Rojas MM, Wenzel SE, Lafyatis R, Modena B, Weathington NM. ?-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome. Am J Physiol Lung Cell Mol Physiol. 2021 11 01; 321(5):L837-L843.
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Tak U, Dokland T, Niederweis M. Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis. Nat Commun. 2021 01 15; 12(1):394.
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Grim JC, Aguado BA, Vogt BJ, Batan D, Andrichik CL, Schroeder ME, Gonzalez-Rodriguez A, Yavitt FM, Weiss RM, Anseth KS. Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):e296-e308.
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Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 03; 62(3):354-363.
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Zheng X, Fernando V, Sharma V, Walia Y, Letson J, Furuta S. Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase cofactor BH4-induces immunostimulatory-shift of breast cancer. Biochem Pharmacol. 2020 06; 176:113887.
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