Signaling Lymphocytic Activation Molecule Associated Protein
"Signaling Lymphocytic Activation Molecule Associated Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing adaptor protein that contains a single SH2 DOMAIN and is essential for the regulation of SLAM FAMILY RECEPTORS in the immune response. Mutations in the SLAM-associated protein gene have been identified in cases of X-LINKED LYMPHOPROLIFERATIVE DISEASE.
Descriptor ID |
D000071179
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MeSH Number(s) |
D12.644.360.024.332 D12.776.157.057.166 D12.776.476.024.426
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Associated Protein".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Associated Protein".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Associated Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in Profiles.
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Lankester AC, Visser LF, Hartwig NG, Bredius RG, Gaspar HB, van der Burg M, van Tol MJ, Gross TG, Egeler RM. Allogeneic stem cell transplantation in X-linked lymphoproliferative disease: two cases in one family and review of the literature. Bone Marrow Transplant. 2005 Jul; 36(2):99-105.
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Sumegi J, Seemayer TA, Huang D, Davis JR, Morra M, Gross TG, Yin L, Romco G, Klein E, Terhorst C, Lanyi A. A spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses. Leuk Lymphoma. 2002 Jun; 43(6):1189-201.
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Sumegi J, Huang D, Lanyi A, Davis JD, Seemayer TA, Maeda A, Klein G, Seri M, Wakiguchi H, Purtilo DT, Gross TG. Correlation of mutations of the SH2D1A gene and epstein-barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease. Blood. 2000 Nov 01; 96(9):3118-25.
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